Thyroid UK

NDT sublingual or swallow whole ?

Hi there

I thought I read that NDT should be taken sublingually and have been doing so for 6 weeks but now Ive just read it should be swallowed whole as the molecules are too large to pass through the mucus membranes.

My question is, as I have been taken it sublingually ( up to 3 grains ) does that mean im massively underdosed and should I start back to the beginning or would it be safe to just multidose 3 times a day but now swallow ??

I dont feel optimal, am on holiday and am suffering from heart palps this week and horrendous aches.

Help, please knowledgable people. 😳

5 Replies

I've read that you should swallow it with water. If it's made to be swallowed, there may be reasons it will not work as well sublingually. Perhaps you aren't under dosed since you are taking a hefty dose.

There may be good reasons for not going directly into the bloodstream as well but STTM seems to disagree.

You could contact the manufacturer and ask them directly.


All thyroid hormone tablets have to be taken with a full glass of water approx 1 hour before eating. The reason for this is that the molecules in thyroid tablets are too large to be absorbed through out tongue. They are made to be dissolved in our stomach that's why a glass of water is advised as it could swell in gullet.

This maybe of interest:

Also make sure your vitamins and minerals are optimum, i.e. B12, Vit D, iron, ferritin and folate.

The above links are by a researcher/scientist/doctor.



I have just started NDT and swallow it whole with a glass of water on an empty stomach, but I don't think you need to worry about taking it sublingually as it appears many do.

STTM states although "some" literature says the molecules are too big, many patients report a good result when taking it sublingually, especially with Erfa, Acela and Thyroid. Some even chew it up.

They also say it is false to take it on an empty stomach (controversial or what ? ? ) ...


Taking NDT Sublingually


1 like

I take thiroyd sublingually and it works perfectly for me and definitely a little stronger than swallowing! I feel a little under medicated if I'm in a rush in the morning and swallow instead of sublingual.

Who knows if it is placebo effect though?

I'd try swallowing though if sublingual doesn't work for you.


On the occasions when I have tried out the sublingual way just for giggles, I concluded that most of it goes down with saliva and therefore it is pretty much the same as if you took it whole - but now it is dissolved in the saliva. I was told that you need to get it through your esophagus ASAP because it can corrode your mucus membranes if you absorb the pill there and there is no "cure" for an abyss in that area. Maybe you can get an abyss under your tongue if you keep sublingualling it. BTW, this is just simple logic, not a medical opinion.


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