Hi. I started self medicating with T3 last September. I didn't see any immediate effect but did have a brief spell of feeling better after a month or so, but now I feel worse again and I don't know what to do next. I'm surprised how little effect the T3 had on me as I know some people have said they noticed immediate changes. I currently take 125 thyroxine and 12.5 tyrosine (T3). I decided to drop my thyroxine a few days ago to 100 as I've been getting skin reactions again, dry skin patches and my granuloma annulare is getting bigger again. I feel exhausted, aching muscles and somewhat low mood. im already supplementing a number of vitamins and minerals. I wasn't sure whether to try dropping my thyroxine and upping my T3 or whether to try NDT when I run out of T3 in a few months. Any advice would be great, thanks.