Two weeks ago I changed from levothyroxine 50mcg onto Thiroyd. I started at 25mcg and .5 grain Thiroyd. But by the afternoon I felt my voice getting raspy and deep and took another .5 grain which alleviated the low symptom. I felt good. But I started noticing that my raspy voice starting earlier during the day so then took another .5 grain. A few days later I dropped the 25mcg levo and just took the Thiroyd. I am now taking .5 grain on waking approx 7am, but by 10.30 feeling my deep voice return and take another .5 grain. Early afternoon again my voice goes deep so I take another .5 grain and again late afternoon. How come I have to take over 2 grains to feel normal instead of 50mcg? I also wonder what happens during the night when not taking the Thiroyd, does the T3 totally deplete? I did take .25 grain early evening then noticed my pulse was slightly raised and I didn't sleep well as I was listening to it. Are all the NDT's made up the same or are some weaker? I just wonder if Thiroyd from Thailand is weaker than others. I am feeling good but taking so many doses makes it difficult to eat and take vitamins without being near taking Thiroyd.