Help people! Tpo anti bodies test

[flashinthepan]

What does it mean when u have a tpo antibody level of 10? Is that bad or good?

[helvella Administrator Thyroid UK]

TPO antibody tests have highly variable ranges. Some labs scale them so that 0-99 is negative, 100 to 199 is "uncertain" and 200 or over is positive (or something like that). Other labs don't. And depending on the technology used, the ranges do vary a lot.

You simply have to use the reference range of the lab that did the test. Call them. Look up their website which might have the ranges. Ask your GP if you have to!

[Clutter in reply to helvella]

Helvella, <34 is ususally negative although my local range is <100 and the highest I've seen is <160.

[helvella Administrator Thyroid UK in reply to Clutter]

A quick grab of a few labs:

cmft.nhs.uk

< 50

walsall

Thyroid Peroxidase (TPO) Antibodies

Numerical result reported. Normal <50 IU/ml

Borderline 50-75 IU/ml

Elevated >75IU/ml

Heart of England

< 5.61U/mL - Negative

> 5.62 <30 IU/mL - Equivocal

>30 IU/mL - Positive

Southend

Reference Range

<50 U/mL Negative

50 - 75 U/mL Borderline

>75 U/mL Positive

[Clutter in reply to helvella]

Heavens, that is a huge variance

[helvella Administrator Thyroid UK in reply to Clutter]

A few more:

cddft.nhs.uk/GP_Pathology_H...

Reference Range < 59 IU/mL

pathology.imperial.nhs.uk/i...

Reference Range

<75 AU/mL

nhspathology.fph.nhs.uk/Cor...

Reference Range:

Negative <50 IU/ml

Borderline 50 - 75 IU/ml

Positive >75 IU/ml

hampshirehospitals.nhs.uk/u.....

Thyroid peroxidase

ELISA

Gold top gel tube

0‐70 Iu/mL

Addenbroke’s Hospital

normal value >60 U/ml

Immunology Rotherham General Hospital

0 – 60 U/L

eastcheshire.nhs.uk/.../ECT......

TPO (thyroid peroxidase) antibody 0-35 kiu/L (values 36-150 indicate a low titre)

kingspath.co.uk/.

<60 IU/ml

tamesidehospital.nhs.uk

0 – 9 IU/l

So far, I have not seen any with the scaled ranges. But I'd have to check every lab to be sure there weren't any in the UK.