I am asking this for a friend. I have asked this on FB Thyroid Friends UK and was recommended to as this here.
My friend went to see an endo privately and was put on T4/T3 combo. She had been on 75 mcgs Levo and when she saw the endo it was suggested she did a trial of the combo as it looked like she wasn't converting T4 to T3 adequatley.
She kept at the usual dose of 75 mcgs Levo but added 5mcgs T3 in mornings to start with. Then she added 5mcgs T3 in the afternoon. After a few days she took 75Mchs Levo + 10mcgs T3 in the mornings and kept at 5mcgs T3 in the aftwernoons. When this seemed ok she increased the afternoon dose to 10mcgs T3. So basically after two weeks she was on 75mcgs T4 and 20mcgs T3 daily. This was the dose the endo had said to do.
So to summarise:-
After about 6 full days on this dosing she started getting tightness in her chest and throat constriction. On advice she stopped her T3 last Friday. She had been on combo levo 75mcgs and T3 20mcgs. She had been on full dosing of T3 for approx 6 days before thus problem started. She didn't reduce her levothyroxine before starting the T3 but when this chest tightness started she reduced it to 50mcgs.
She had blood tests done on Monday and results are as follows :-
T3 3.5 (3.2-5.75) t4 13.4 ( 0.9-20) tsh 0.30 (0.35-4.75)
Any ideas what's going on.
On Friday she was told to stop the T3 but increase levo again to 75mcgs but she has held off doing the increase.