Had a number of B12 tests, should I take B12/su... - Thyroid UK

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Had a number of B12 tests, should I take B12/supplements now, or get active b12 test?

Hi everyone. Over the last few months I’ve put a few posts on here about my concerns about having low B12. My test results are as follows:

Serum B12: 182 ng/l (180-1000) and a few weeks later 202 ng/l

Homocysteine: 9.9 mmol/l

MMA: 0.25 umol/l

Serum folate: 5ug/l

Vitamin D: 44.5 nmol/L (it had dropped to 34.5, but have been now taking 6,000IU a day, so I think it’s increasing)

Anti-Intrinsic factor: Negative

I have bought some Jarrows 5,000mcg B12 Methylcobalamin and a good quality whole-food multi supplement. Before I start taking these I was considering having the active b12 test to see what it was, since once I start taking the B12 I know that this result will not be a reliable indicator due to the supplements. However, the active test needs a GP referral, and while my GP did order the additional tests I asked for, he has now adamantly told me that I do not have B12 problems, so won’t give me the referral.

So my question is, should I forget about having the test and just start taking the supplements, or investigate the much more expensive Blue Horizon active b12 test? I’ve been waiting a while for the results of my MMA test, and so have been putting off taking the B12/supplements. I don’t want to keep waiting though as things won’t improve (well let’s hope so anyway) until I do start taking the B12/supplements.

So what's your thoughts?

Cheers :)

12 Replies

Whitenoise, you may get more help with B12d from facebook.com/groups/1749289... or healthunlocked.com/pasoc

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Suppose it's not really a good idea to do a duplicate post in that group, anyway this can be moved? I shall take a look at the facebook group as well Clutter, thanks.

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Whitenoise, Why not copy and paste your post? I was thinking you'd get advice on your homocysteine and MMA.


Did you have the Blue Horizon B12 test or was it your GP? If it was Blue Horizon, they do the active B12 test.


The GP just did the normal serum B12 test.


Have you had the (Holo TC ) blood test to determine if deficiency of B12 at a cellular level.

If not, don't start to supplement until after your test.

The cost privately,for me was 25.00.

I am awaiting my MMA results from the London lab, but there has been a delay due to a problem with there equipment.


No I haven't had that test done as this is the 'active' test I was referring too.

Where did you get it for £25.00? The cheapest I'd seen was £18+£12 postage from the NHS hospital in London. However, this requires a GP referral letter which I can't get.


I did my test privately.

I didn't need a GP to give consent, if I am paying to have these blood tests done.

My GP only goes on the standard B12 blood test, and going by her test, mine was within normal range.

I now know, that she would never have consented to having the (HoloTC) done.

I have been told that I won't need my homocysteine level checked, that the MMA will be all I need.

You said, you were waiting for your MMA results to come back, so I assumed you had your Active B12 blood test done.

Why not try Blue Horizon, as marram has suggested.


Thanks for the information manukia. I looked at Blue Horizon, but I think it was something like £90 or something to have the test. You mentioned you were getting yours privately, but from where at £25? Cheers.


My very good local hospital.


Ah I see. Assuming this was a private hospital like a Nuffield or a Spire or something of that like, or was it just done privately at an NHS hospital? I mention this as there is a Nuffield hospital near me, so I might contact them.


I hope you can get the Active B12 blood test done, it does take sometime to get the results back.

Kind regards



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