Hi all this is my 1st ever blog. I've been in remission for 5yrs after total thyroidectomy and removal of 52 lymph nodes due to papillary cancer that had spread. I also have Crohn's disease and ankylosing spondilytis it's thought an immunosuppressant caused the cancer. After radioactive iodine treatment my tsh has to be fully suppressed. This has been the case until recently when levels have started to rise the answer to increase thyroxine meds. However my level has remained unchanged after 8wks of 275mcg I am now on 300mcg! I'm really tired all the time and very stressed that the cancer may return even though thyroglobulin remains unrecordable. My doctors say there's nothing to worry about but shouldn't I feel symptoms of being hyper rather than the hypo that I feel? If anyone has similar experience I'd love to hear.