IBS d and antihistamines

[Moviemakee]

Having spent the last week with bloating, loose stools, anxiety and feeling generally awful....I've turned to Dr google. To my surprise I've found numerous references to the use of antihistamines for ibs d. Does anyone have any experience and success with them please?

[BabsyWabsy]

I have multiple allergies and am on an antihistamine twice a day on prescription. As I have been on this for donkey's years, it is hard to say if it helps my gut issues. So, I suppose this might be trial and error for you. Worth a try I suggest.

[Moviemakee in reply to BabsyWabsy]

Thanks for your reply...think I will give them a go.

[xjrs]

I did some research into the use of Ebastine, an anti-histamine for IBS. The main issue is that anti-histamines can have systematic side effects such as headaches, sleepiness, and dry mouth:

downloads.dokteronline.com/...

Until researchers come up with a way of delivering the anti-histamine effects directly to the gut and not impact any other part of the body, I'd be wary of taking these purely for IBS.

If you're interested in general advice about IBS and in particular various drugs for IBS, you may find some information on this website useful:

ibsresearcher.com/

[Moviemakee in reply to xjrs]

Thank you for your reply and information...I guess we all get to a point where we are desperate for a solution in whatever form.

[xjrs in reply to Moviemakee]

Indeed. That's why I ended up doing my own research, which I'd put on that website, so people can find out what's available for free. I can certainly see why you'd looked into it, though, since there has been some studies on it.

[Bracondale]

When I had particularly severe and long lasting issue IBS-D following Covid/travel abroad I looked into antihistamines (specifically those that target gut histamine receptors) as a way of calming things down (albeit just masking the underlying problem). Those that seemed most researched/effective were not available/only by prescription. So I dug deeper into underlying cause and alighted upon mast cell stabilisers and Elixa probiotics (success with which I have talked about in another post 'Elixa Probiotics posted by KlayPigeon')

[Moviemakee in reply to Bracondale]

Thanks for your reply...I'll take a look at Elixa Probiotics,