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Darolutamide (Nubeqa) Vs Enzalutamide ( Xtandi)
Are there any studies comparing efficacy and side effect profile of darolutamide Vs enzalutamide when given together with first generation ADT ? I read that darolutamide does not cross blood brain barrier so may have lesser side effects ?
Are there any studies comparing efficacy and side effect profile of darolutamide Vs enzalutamide when given together with first generation ADT ? I read that darolutamide does not cross blood brain barrier so may have lesser side effects ?
Tinkudi
in
Advanced Prostate Cancer
8 days ago
Headaches and nightmares on T3 monotherapy
Hi, does anyone else get headaches and nightmares on T3 monotherapy? I have read the side effects leaflet and it states that 'headache' and 'insomnia' are two of the side effects; since I have been on T3 only I often wake up in the night and have a very light sleep compared to what I am used to, then
Hi, does anyone else get headaches and nightmares on T3 monotherapy? I have read the side effects leaflet and it states that 'headache' and 'insomnia' are two of the side effects; since I have been on T3 only I often wake up in the night and have a very light sleep compared to what I am used to, then
Denise500
in
Thyroid UK
9 days ago
Low TSH advice and breast cancer
I’ve been hypo for 25 years . October 23, non fasted , 12 hours after last dose of Levi , annual bloods showed TSH 0.1 (0.2-6) and T4 18.9.(12-22). Recommended retest in 6 months . I saw private endo ( useless ) who did fasted bloods . TSH 4.5 , T4 16.8 and T3 3.9 Levo was 24 hours before bloods
I’ve been hypo for 25 years . October 23, non fasted , 12 hours after last dose of Levi , annual bloods showed TSH 0.1 (0.2-6) and T4 18.9.(12-22). Recommended retest in 6 months . I saw private endo ( useless ) who did fasted bloods . TSH 4.5 , T4 16.8 and T3 3.9 Levo was 24 hours before bloods
farrellkl68
in
Thyroid UK
9 days ago
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Unusual case
Short summary. 79 years old. Surgery 12 years ago on G4+3. Recurrence 3 years later. IMRT and second recurrence 3 years later. No ADT. PSADT 1.5 years and now it's 2.3. Two PSMA scans. First showed nothing. Second showed ill defined area in prostate bed that might be positive. Never had ADT.
Short summary. 79 years old. Surgery 12 years ago on G4+3. Recurrence 3 years later. IMRT and second recurrence 3 years later. No ADT. PSADT 1.5 years and now it's 2.3. Two PSMA scans. First showed nothing. Second showed ill defined area in prostate bed that might be positive. Never had ADT.
npac
in
Advanced Prostate Cancer
9 days ago
PD and Prostate Cancer
...that is, there is never an end to the worst. I will soon have to undergo radiotherapy for prostate cancer. I am currently undergoing hormone therapy. I am looking for similar experiences and above all advice on how to manage this new situation in cohabitation with PD. Thank you very much.
...that is, there is never an end to the worst. I will soon have to undergo radiotherapy for prostate cancer. I am currently undergoing hormone therapy. I am looking for similar experiences and above all advice on how to manage this new situation in cohabitation with PD. Thank you very much.
Fed1000
in
Cure Parkinson's
9 days ago
Treatment awaited
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Hi all I just completed my history incorrectly as a post. I have not posted before as I have been a silent member without any worrying ongoing elevations in PSA for about four years. I have keenly observed the posts of members and learned a good deal from them. This post is the follow up on my history
Sisyphus
in
Advanced Prostate Cancer
10 days ago
My History to date
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Diagnosed 09/2019 PSA 12.8 T2C Grade Group 5 - (4+5) Cores right posterior @15mm length, cores right mid and left posterior Grade Group 4 MRI showing Pi-Rads 5 lesion right side successfully targeted N0 Pet PSMA showing avidity right side of prostate and two avid lymph nodes common iliac and external
Sisyphus
in
Advanced Prostate Cancer
10 days ago
Gleason 6 Treatment options .
Has anyone experienced Monotherapy - LDR Brachytherapy , without , EBRT or ADT . for Grade1 ( Gleason Score 3+3=6 Prostate Cancer ? OR LDR With EBRT Only ?
Has anyone experienced Monotherapy - LDR Brachytherapy , without , EBRT or ADT . for Grade1 ( Gleason Score 3+3=6 Prostate Cancer ? OR LDR With EBRT Only ?
Conlig1940
in
Advanced Prostate Cancer
10 days ago
Please share your experiences and thoughts.
My last psma scan results are below. Please share your thoughts and experiences regarding my psma results. Is this a bad report or reasonably good?. My psa is undetectable. I am on ADT vacation now for the last 7 months. Should I start ADT now or wait untill psa is detectable? 1. SPLEEN: No new
My last psma scan results are below. Please share your thoughts and experiences regarding my psma results. Is this a bad report or reasonably good?. My psa is undetectable. I am on ADT vacation now for the last 7 months. Should I start ADT now or wait untill psa is detectable? 1. SPLEEN: No new
Ahk1
in
Advanced Prostate Cancer
10 days ago
Update on Treatment
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
In June 2023, a routine PSA test value turned out to be 4.6, did an MRI; Diagnosed with Prostate Cancer, Gleason Score 7 (3+4), biopsy said one core. (Details in my profile). Opted for Active Surveillance. But in Oct 2023, PSA level went to 6.1 and in Jan 2024 PSA went to 9.2 In March 2024, did another
Sushupthi
in
Advanced Prostate Cancer
11 days ago
advice please!
Hello. I was diagnosed about a year ago with stage 4 prostate cancer. I was on hormone therapy but that is no longer surprising the cancer. It is in my bones, currently spreading in my pelvic bone and lumbar. I hope to start chemotherapy in the next month. But with my current health I don’t know
Hello. I was diagnosed about a year ago with stage 4 prostate cancer. I was on hormone therapy but that is no longer surprising the cancer. It is in my bones, currently spreading in my pelvic bone and lumbar. I hope to start chemotherapy in the next month. But with my current health I don’t know
BonnieKlyde
in
Advanced Prostate Cancer
12 days ago
ADT and creativity
I am a composer. Since I had ADT (Eligard - last shot in early April) I have experienced the conventional side effects - hot flashes, larger breasts, shrunken penis, no libido, tiredness. I am hoping those diminish over time. My question is to those who are occupational "creatives" - artists, writers
I am a composer. Since I had ADT (Eligard - last shot in early April) I have experienced the conventional side effects - hot flashes, larger breasts, shrunken penis, no libido, tiredness. I am hoping those diminish over time. My question is to those who are occupational "creatives" - artists, writers
Eadgbe
in
Prostate Cancer Network
12 days ago
Looking for any Info for Recent PC Diagnosis
I’m a 62 year old, recently diagnosed with advanced prostate cancer. I’ve been on hormone therapy for 2 weeks and see my oncologist in a week. My PC seems to be aggressive and my PSA is off the charts 885! I would love any positive info I can get.
I’m a 62 year old, recently diagnosed with advanced prostate cancer. I’ve been on hormone therapy for 2 weeks and see my oncologist in a week. My PC seems to be aggressive and my PSA is off the charts 885! I would love any positive info I can get.
Iber
in
Advanced Prostate Cancer
12 days ago
Dosage question.
I was diagnosed with Graves and overactive thyroid forty four years ago. I had a thyroidectomy and started on synthetic thyroid hormone therapy. I’m 69 now and take 100 mcg of Levothyroxine daily, my TSH is 0.291, low. What dose should I be taking?
I was diagnosed with Graves and overactive thyroid forty four years ago. I had a thyroidectomy and started on synthetic thyroid hormone therapy. I’m 69 now and take 100 mcg of Levothyroxine daily, my TSH is 0.291, low. What dose should I be taking?
UndertheTuscanSun
in
Thyroid UK
12 days ago
six years ago today!
It is early in the morning and I felt that I needed to tell somebody this info. It needs to be people that can really understand….. that’s where the people in this community come in, since you understand what we go through! Six years ago today I was diagnosed with stage 4, 4 plus 3 w over 25 metastases
It is early in the morning and I felt that I needed to tell somebody this info. It needs to be people that can really understand….. that’s where the people in this community come in, since you understand what we go through! Six years ago today I was diagnosed with stage 4, 4 plus 3 w over 25 metastases
Fitzbruce1
in
Advanced Prostate Cancer
12 days ago
Results Advice Needed Please
Hiya! I'd be most grateful if the wise owls of this forum can shed some light on my results, especially the vitamin tests. I am pretty much constantly symptomatic even though my thyroid results seem pretty optimal for NDT use. I also have early onset menopausal osteoporosis, which is being managed.
Hiya! I'd be most grateful if the wise owls of this forum can shed some light on my results, especially the vitamin tests. I am pretty much constantly symptomatic even though my thyroid results seem pretty optimal for NDT use. I also have early onset menopausal osteoporosis, which is being managed.
MindfulMoments
in
Thyroid UK
12 days ago
Over medicating
I've recently had some help from the great people on here regarding my thyroid problems, which I am super thankful for but I think I need more. I've mentioned previously the horrible anxiety/restlessness/claustrophobia type symptoms I've had for a few weeks now and recently had a private blood draw to
I've recently had some help from the great people on here regarding my thyroid problems, which I am super thankful for but I think I need more. I've mentioned previously the horrible anxiety/restlessness/claustrophobia type symptoms I've had for a few weeks now and recently had a private blood draw to
ci00aaj
in
Thyroid UK
13 days ago
How I Cope With ADT
Episode 10 of My Journey With Prostate Cancer playlist. This episode is less satirical, just hoping somebody finds something in it useful. https://youtu.be/HMxB8DBM1X4?si=Mx81mBr1x_6ClBLn
Episode 10 of My Journey With Prostate Cancer playlist. This episode is less satirical, just hoping somebody finds something in it useful. https://youtu.be/HMxB8DBM1X4?si=Mx81mBr1x_6ClBLn
Caldonia
in
Advanced Prostate Cancer
13 days ago
Suppressed TSH and getting optimum on NDT
I'm being treated by a private thyroid Dr for hypothyroid, I'm on NDT Armour and I've been slowly titrating for 12 months from zero treatment. I couldn't get treatment on the NHS. My latest results show TSH at 0.01. My T4 and T3 are the highest they've ever been and I feel much better than I did last
I'm being treated by a private thyroid Dr for hypothyroid, I'm on NDT Armour and I've been slowly titrating for 12 months from zero treatment. I couldn't get treatment on the NHS. My latest results show TSH at 0.01. My T4 and T3 are the highest they've ever been and I feel much better than I did last
Insomania
in
Thyroid UK
13 days ago
Help Please With Thyroid & Vitamin Results.
Hiya! I'd be most grateful if the wise owls of this forum can shed some light on my results, especially the vitamin tests. I am pretty much constantly symptomatic even though my thyroid results seem pretty optimal for NDT use. I also have early onset menopausal osteoporosis, which is being managed.
Hiya! I'd be most grateful if the wise owls of this forum can shed some light on my results, especially the vitamin tests. I am pretty much constantly symptomatic even though my thyroid results seem pretty optimal for NDT use. I also have early onset menopausal osteoporosis, which is being managed.
MindfulMoments
in
Thyroid UK
13 days ago
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