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Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
6 months ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
6 months ago
NDT at reasonable prices?
What site is there that has NDT at reasonable prices that i can get online? I am in America and it isnt sold here because the fda won't allow it.
What site is there that has NDT at reasonable prices that i can get online? I am in America and it isnt sold here because the fda won't allow it.
MarksWife0213
in
Thyroid UK
6 months ago
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Newly diagnosed researching lifestyle changes
Hi there, Had a overall physical of everything which included PSA which was 6 in 2016 and didn't put any attention to it and ignored it, nobody I spoke with who saw the report said to do anything. No family history of prostate cancer that I know of. Now 7 years later age 64, PSA 18, Free PSA 11%
Hi there, Had a overall physical of everything which included PSA which was 6 in 2016 and didn't put any attention to it and ignored it, nobody I spoke with who saw the report said to do anything. No family history of prostate cancer that I know of. Now 7 years later age 64, PSA 18, Free PSA 11%
Nwdx
in
Advanced Prostate Cancer
6 months ago
Life Expectancy
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
godhelpus
in
Advanced Prostate Cancer
6 months ago
Staring at my unopened bottle of Orgovyx
Well, D-day (or maybe O-day) has arrived (thank you FED-X). I'm about to do a swan dive into my battle against my PCa. After a week of searching for this stuff, my clinic found it in Louisville Kentucky at a pharmacy called Onco360. Not exactly a neighborhood corner market with me living on an island
Well, D-day (or maybe O-day) has arrived (thank you FED-X). I'm about to do a swan dive into my battle against my PCa. After a week of searching for this stuff, my clinic found it in Louisville Kentucky at a pharmacy called Onco360. Not exactly a neighborhood corner market with me living on an island
mababa
in
Advanced Prostate Cancer
6 months ago
T3 side effects
hi, Please can I have some advice. I’ve been taking 10 mcg T3 for 7 months together with 75 mcg T4. I haven’t felt particularly any better on T3 except for an improvement in tiredness and mood. I’ve felt hyped up and breathless on exertion so I asked for an ECG. I’m 68 and they found that I have a
hi, Please can I have some advice. I’ve been taking 10 mcg T3 for 7 months together with 75 mcg T4. I haven’t felt particularly any better on T3 except for an improvement in tiredness and mood. I’ve felt hyped up and breathless on exertion so I asked for an ECG. I’m 68 and they found that I have a
Essexlil
in
Thyroid UK
6 months ago
Effect of Baseline T on T-Recovery Time
Here's a plot of % of Men who recover their baseline testosterone after stopping ADT (Lupron), as a function of ADT duration for two different groups: (A) men who had a
normal
baseline testosterone (red line), and (B) men who had a
low
baseline testosterone (green line). Increasing the
Here's a plot of % of Men who recover their baseline testosterone after stopping ADT (Lupron), as a function of ADT duration for two different groups: (A) men who had a
normal
baseline testosterone (red line), and (B) men who had a
low
baseline testosterone (green line). Increasing the
janebob99
in
Prostate Cancer Network
6 months ago
Testosterone Recovery for 50% of Men
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
janebob99
in
Prostate Cancer Network
6 months ago
Testosterone Recovery After ADT - Updated Plot
Thanks to Tall_Allen for providing lots of extra data for this plot: https://www.prostatecancer.news/2023/04/intermittent-adt.html You can easily extrapolate the curves to find out your recovery time. ADT duration of 3-9 months fall roughly on the same curve, and ADT of 18-24 roughly fall on the same
Thanks to Tall_Allen for providing lots of extra data for this plot: https://www.prostatecancer.news/2023/04/intermittent-adt.html You can easily extrapolate the curves to find out your recovery time. ADT duration of 3-9 months fall roughly on the same curve, and ADT of 18-24 roughly fall on the same
janebob99
in
Prostate Cancer Network
6 months ago
Testosterone recovery after stopping ADT - 3
This plot shows the % of men who recovered their original testosterone level after stopping Lupron ADT, plotted versus the time (months) after stopping ADT, for three different durations of ADT (4, 6-12, or 24 months). The curves show that a short course of ADT allows men to recover their testosterone
This plot shows the % of men who recovered their original testosterone level after stopping Lupron ADT, plotted versus the time (months) after stopping ADT, for three different durations of ADT (4, 6-12, or 24 months). The curves show that a short course of ADT allows men to recover their testosterone
janebob99
in
Prostate Cancer Network
6 months ago
Testosterone Recovery after stopping ADT -2
This plot shows the time after stopping Lupron ADT for the testosterone to recover to the original level for 50% of men, plotted versus Duration of ADT treatment (4 or 24 months). The longer the duration of ADT, the longer it takes to recover the original testosterone level, which makes sense. For
This plot shows the time after stopping Lupron ADT for the testosterone to recover to the original level for 50% of men, plotted versus Duration of ADT treatment (4 or 24 months). The longer the duration of ADT, the longer it takes to recover the original testosterone level, which makes sense. For
janebob99
in
Prostate Cancer Network
6 months ago
Testosterone Recovery after stopping ADT -1
Here's the first of four plots showing testosterone recovery after stopping Lupron ADT. The testosterone recovers quickest in the first 12 months, but then flattens out after that.
Here's the first of four plots showing testosterone recovery after stopping Lupron ADT. The testosterone recovers quickest in the first 12 months, but then flattens out after that.
janebob99
in
Prostate Cancer Network
6 months ago
Thoughts on Denosumab in my case
MO is suggesting Denosumab after my Dexa scan. Bone density normal in spine, osteopenia in right hip and osteoporosis on one part of left hip. I am wondering if with a -2.7 it is possible to control/improve with supplements and weight bearing exercises? What are you taking? Have added calcium. The
MO is suggesting Denosumab after my Dexa scan. Bone density normal in spine, osteopenia in right hip and osteoporosis on one part of left hip. I am wondering if with a -2.7 it is possible to control/improve with supplements and weight bearing exercises? What are you taking? Have added calcium. The
Hope49823
in
Advanced Prostate Cancer
6 months ago
PSMA PET Scan Frequency?
Hello forum members. This is my first post but have learned so much here, thanks to the contributors on this site. My husband’s last and only PSMA PET scan was 1.5 years ago showing 6 mets in small bones after PSA consistently rose a year after radiation. The standard ADT treatment was prescribed
Hello forum members. This is my first post but have learned so much here, thanks to the contributors on this site. My husband’s last and only PSMA PET scan was 1.5 years ago showing 6 mets in small bones after PSA consistently rose a year after radiation. The standard ADT treatment was prescribed
EatLovePray
in
Advanced Prostate Cancer
6 months ago
genetic tests for conversion issues etc
hi lovely forum users I’ve finally got an endo appointment via my doctor no date yet. I doubt they’ll smile on my taking ERFA but I’ve no intention of going back to Levo only as it worked less and less for me over the years. I’ve wondered if I have a T4 to T3 conversion issue and have found a blue horizon
hi lovely forum users I’ve finally got an endo appointment via my doctor no date yet. I doubt they’ll smile on my taking ERFA but I’ve no intention of going back to Levo only as it worked less and less for me over the years. I’ve wondered if I have a T4 to T3 conversion issue and have found a blue horizon
Starseed56
in
Thyroid UK
6 months ago
NDT Source - PM Only
Hi. All of my Thyroid was removed in 2008 & I'm T3 only - Poisoned by T4. I've managed to keep my T3 Px. A few years ago I started NDT + T3 & I feel a lot better than I did on T3 Only.I've tried a few different NDT brands & I'm ok with all of them. I'm on Thyroid-S at the moment. I live in the UK. I've
Hi. All of my Thyroid was removed in 2008 & I'm T3 only - Poisoned by T4. I've managed to keep my T3 Px. A few years ago I started NDT + T3 & I feel a lot better than I did on T3 Only.I've tried a few different NDT brands & I'm ok with all of them. I'm on Thyroid-S at the moment. I live in the UK. I've
Lily905
in
Thyroid UK
6 months ago
A Neophyte's Experience with a Gummy
Some of you might be interested in my gummy experience. I do not advocate anything here, but just want to share a new experience. Outside of four episodes in my eighty-four plus years, I have not used marijuana or other drugs beyond alcohol, coffee, maté from the Pampas of Argentina, and whatever uppers
Some of you might be interested in my gummy experience. I do not advocate anything here, but just want to share a new experience. Outside of four episodes in my eighty-four plus years, I have not used marijuana or other drugs beyond alcohol, coffee, maté from the Pampas of Argentina, and whatever uppers
Worked_the_World
in
Advanced Prostate Cancer
6 months ago
Full body MRI?
We’ve been reading about full body MRIs and wonder if anyone has had one after radiation treatment for prostate cancer? Can this type of test pick up micro metastases? If the full body scan was “all clear” could ADT be shortened from 2 years to a lower amount?
We’ve been reading about full body MRIs and wonder if anyone has had one after radiation treatment for prostate cancer? Can this type of test pick up micro metastases? If the full body scan was “all clear” could ADT be shortened from 2 years to a lower amount?
Oatmeal2
in
Advanced Prostate Cancer
6 months ago
PSA rising on Triplet Therapy after <18m
Hi all. Hope you are keeping your spirits high. This is a follow up to a post I made in 2022 about my father. I haven't posted since, which reflects the period of relative normalcy that followed the commencement of ADT (triplet therapy) at MSK. I want to pause to appreciate that since I know most of
Hi all. Hope you are keeping your spirits high. This is a follow up to a post I made in 2022 about my father. I haven't posted since, which reflects the period of relative normalcy that followed the commencement of ADT (triplet therapy) at MSK. I want to pause to appreciate that since I know most of
nyc_son
in
Advanced Prostate Cancer
6 months ago
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