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Zytiga vs Nubeqa for Triple Therapy
Hi, I've recently received a diagnosis of Stage 4 prostate cancer, which is high volume and hormone-sensitive. I've consulted with 3 oncologist and all recommend triple therapy: Lupron alongside 6 rounds of Docetaxel, plus an ARPI. While two oncologists recommend Nubeqa, one strongly advocates for Zytiga
Hi, I've recently received a diagnosis of Stage 4 prostate cancer, which is high volume and hormone-sensitive. I've consulted with 3 oncologist and all recommend triple therapy: Lupron alongside 6 rounds of Docetaxel, plus an ARPI. While two oncologists recommend Nubeqa, one strongly advocates for Zytiga
littleCar
in
Advanced Prostate Cancer
3 months ago
Reference Library of Papers about Dutasteride for Treating Prostate Cancer
Here is a library of 20 papers about using Dutasteride to treat prostate cancer. In one study, Dutasteride monotherapy reduces PSA by 50%, reduces prostate volume by 25%, and reduces tumor volume by 30%, after 6 months of treatment, compared to placebo (Moore, 2017). https://pubmed.ncbi.nlm.nih.gov
Here is a library of 20 papers about using Dutasteride to treat prostate cancer. In one study, Dutasteride monotherapy reduces PSA by 50%, reduces prostate volume by 25%, and reduces tumor volume by 30%, after 6 months of treatment, compared to placebo (Moore, 2017). https://pubmed.ncbi.nlm.nih.gov
janebob99
in
Advanced Prostate Cancer
3 months ago
2018 still kicking
Good morning, Brothers. I was diagnosed on February 27th, 2018, and just got my most recent report. PSA is still 0.1 bone mets, which are still multiple but stable, either no uptake or diminished some. My only treatments have been Zytiga and Prendisone with Eligard injection every six months. I also
Good morning, Brothers. I was diagnosed on February 27th, 2018, and just got my most recent report. PSA is still 0.1 bone mets, which are still multiple but stable, either no uptake or diminished some. My only treatments have been Zytiga and Prendisone with Eligard injection every six months. I also
leo2634
in
Advanced Prostate Cancer
3 months ago
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Cholestyramine
My husband has had explosive diarrhea since mid February. After blood tests, stool samples, colonoscopy, and more stool samples, they are not able to determine what is causing the diarrhea. The doctor has prescribed Cholestyramine. Has anyone had experience with this medication and did it help?
My husband has had explosive diarrhea since mid February. After blood tests, stool samples, colonoscopy, and more stool samples, they are not able to determine what is causing the diarrhea. The doctor has prescribed Cholestyramine. Has anyone had experience with this medication and did it help?
lowraind
in
IBS Network
3 months ago
Wife of Newly Diagnosed Husband - PSMA questions
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
Hi Everyone, We found out two weeks ago that my husband has high grade prostate cancer. He is 59. PSA 5.9. Gleason 4+5, 4+3 and 3+4. There was perineural invasion in one sample and intraductal in another. He has had an MRI and a CT scan, as well. He is scheduled for a bone scan next week. No prostate
EvFC
in
Advanced Prostate Cancer
3 months ago
Liquid Biopsy Method Enables Real-Time Monitoring of Metastatic Prostate Cancer…
….and can help in finding new targets for therapies! https://www.insideprecisionmedicine.com/topics/oncology/new-liquid-biopsy-method-enables-real-time-monitoring-of-metastatic-prostate-cancer/
….and can help in finding new targets for therapies! https://www.insideprecisionmedicine.com/topics/oncology/new-liquid-biopsy-method-enables-real-time-monitoring-of-metastatic-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
7 days ago
Metastatic PC that produces no or low PSA
Hi All, Looking to connect with people with metastatic PC that produces no or low PSA I am 44 and was diagnosed with PC with a bone metastasis grade 4+5. My PSA at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga. I would love to connect
Hi All, Looking to connect with people with metastatic PC that produces no or low PSA I am 44 and was diagnosed with PC with a bone metastasis grade 4+5. My PSA at time of diagnosis was 0.54. I’m undergoing PEACE 1 protocol treatment. Finish RT and Doxetaxel still on Zytiga. I would love to connect
Jumpingbellybeans
in
Advanced Prostate Cancer
3 months ago
PSMA PET Results - don’t know what to do next (more tests?)
Hi everyone, For those who have been following my dad was diagnosed with PCa on Jan 18th, PI-RADS 5, Gleason 8, PSA 10.4. He started 50mg of Casodex on March 8, and had Eligard 30mg injection March 26th. He has had bone scan (nothing notable), CT (nothing notable), MRI showed one of his pelvic
Hi everyone, For those who have been following my dad was diagnosed with PCa on Jan 18th, PI-RADS 5, Gleason 8, PSA 10.4. He started 50mg of Casodex on March 8, and had Eligard 30mg injection March 26th. He has had bone scan (nothing notable), CT (nothing notable), MRI showed one of his pelvic
Cafu6
in
Advanced Prostate Cancer
3 months ago
PSA following Lupron and question on scans
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
hi all, I am so happy to report that my dad has really improved following terrible side effects with his radiation treatment. I have posted before -he was having awful GI side effects which seemed to get worse following radiation completion. But this is all subsided which we are grateful for. dad
alysona828
in
Advanced Prostate Cancer
3 months ago
Why don't doctors prescribe Dutasteride more often?
I get this question from a lot of men that have prostate cancer. Although the black label warning is a concern to some doctors, and has been discussed here in previous posts, I think the main reason is simply that most doctors don't know about it. Here is the single best paper reviewing the three major
I get this question from a lot of men that have prostate cancer. Although the black label warning is a concern to some doctors, and has been discussed here in previous posts, I think the main reason is simply that most doctors don't know about it. Here is the single best paper reviewing the three major
janebob99
in
Prostate Cancer Network
3 months ago
Third line chemotherapy, Caelyx
so, have started Caelyx every 4 weeks as carboplatin and paclitaxel and Niraparib have stopped working. Surgery to remove peritoneum and resection liver not an option. Does anyone have experience of just Caelyx? Is it effective on its own? Thankyou
so, have started Caelyx every 4 weeks as carboplatin and paclitaxel and Niraparib have stopped working. Surgery to remove peritoneum and resection liver not an option. Does anyone have experience of just Caelyx? Is it effective on its own? Thankyou
Skyeplus
in
My Ovacome
3 months ago
PSMA Scans and False Positives
So I saw my MO yesterday to review my ongoing treatment of Xtandi and Lupron. Been 3 months so far with no real side effects except hot flashes. My PSMA scan showed prostate and one met to sacrum. Prostate treated with 28 rounds of EBRT. MO says since sacrum is so close to prostrate it might have
So I saw my MO yesterday to review my ongoing treatment of Xtandi and Lupron. Been 3 months so far with no real side effects except hot flashes. My PSMA scan showed prostate and one met to sacrum. Prostate treated with 28 rounds of EBRT. MO says since sacrum is so close to prostrate it might have
Jeffdanger
in
Advanced Prostate Cancer
3 months ago
left side throat ,tongue discomfort
I am very worried though as my brother had
throat
cancer
which started in his tonsil bed, anything unusual in that area really scares me, but I feel my GP will probably just dismiss this feeling.
I am very worried though as my brother had
throat
cancer
which started in his tonsil bed, anything unusual in that area really scares me, but I feel my GP will probably just dismiss this feeling.
Buttsy
in
Scleroderma & Raynaud's UK (SRUK)
9 months ago
Reaction to docetaxel twice now.
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
FortyWinks
in
Advanced Prostate Cancer
3 months ago
Assessing the Benefit of CAR T-cell Therapies for mCRPC
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
God_Loves_Me
in
Advanced Prostate Cancer
14 days ago
FDA approves a new IND application of 225Ac-J591 (Actinium)
The FDA has granted clearance to an investigational new drug (IND) application for 225Ac-J591 (CONV01-α), a prostate-specific membrane antigen-targeted monoclonal antibody under investigation for the treatment of patients with advanced prostate cancer, announced Convergent Therapeutics, the developer
The FDA has granted clearance to an investigational new drug (IND) application for 225Ac-J591 (CONV01-α), a prostate-specific membrane antigen-targeted monoclonal antibody under investigation for the treatment of patients with advanced prostate cancer, announced Convergent Therapeutics, the developer
Maxone73
in
Advanced Prostate Cancer
3 months ago
EBRT - Is it the right thing and what to expect?
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
After DX in November 2018 with Stage IV and Gleason of 5+4 and 4+5, and 5 years of ADT of Lupron (then Orgovyx), prednisone 5mg, and Zytiga 250mg with low fat breakfast, my PSA stayed stable at 0.4 or 0.5. At end of 2013, PSA started rising to latest value of 0.84. Had PSMA PET Scan March 5, 2024
JazzMan42
in
Advanced Prostate Cancer
4 months ago
Eligard and bicalutamide.
Started eligard and bicalutamide post RP in 2018. Followed advice of urologist until 2022. New urologist took me off both after PSA of 0.01. Unfortunately, l did not receive advice about secondary effects of the above drugs-osteoporosis etc. A DEXA scan in 2022 revealed high possibility of bone fractures
Started eligard and bicalutamide post RP in 2018. Followed advice of urologist until 2022. New urologist took me off both after PSA of 0.01. Unfortunately, l did not receive advice about secondary effects of the above drugs-osteoporosis etc. A DEXA scan in 2022 revealed high possibility of bone fractures
edgeh
in
Advanced Prostate Cancer
4 months ago
Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
4 months ago
Degarelix worked for 6 months now on xtandi as well.
Degarelix worked for 6 months now on xtandi as well gleeson score 8 psa has fallen slightly from 323 to 280 how long should i expect xtandi to stop bone pain etc.
Degarelix worked for 6 months now on xtandi as well gleeson score 8 psa has fallen slightly from 323 to 280 how long should i expect xtandi to stop bone pain etc.
littlemount
in
Advanced Prostate Cancer
4 months ago
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