Experiences with

Targeted therapy

Can this be treated with targeted therapy such as Herceptin ( I am not aware of the presence of HER 2 ) but have been told that the surgical option would kill my husband who is 75 yrs old even though CT scan shows no spread . He has not had a PET scan.

I'm on targeted therapy - Retsevmo - 3 days in, so too soon to know how it will go or what my side effects might be like. I'd be interested to hear from anyone else on the same treatment.

Now it's the moment for nectin-4 based ADCs! LY4052031 is an investigational antibody-drug conjugate (ADC) targeting Nectin-4, a protein overexpressed in cancers like prostate, bladder, breast, non-small cell lung cancer, and gastric cancers. Nectin-4’s low expression in normal tissues makes it an ideal

CRB-701 combines a monoclonal antibody with a cytotoxic agent, aiming to deliver targeted therapy to cancer cells while minimizing damage to healthy tissues. In a Phase 1 dose-escalation study, CRB-701 demonstrated promising results.

I'm going to see my oncologist on Wednesday to discuss targeted therapy. My stage was upgraded from 1A to 1B. I had a 18mm non small cell cancer nodule removed and eleven lymph nodes were taken out and all were negative.

PARP inhibitors have emerged as a targeted therapy for prostate cancer, especially in tumors with specific DNA repair defects. By exploiting synthetic lethality, these drugs can selectively kill cancer cells that lack the ability to repair DNA damage.

Acalabrutinb (Calquence) is a second generation BTKi targeted therapy. It was approved for medical use in the United States in 2017 and in the European Union in November 2020.

I am also told I cannot have targeted therapy but I do not know why, that questions has not really been answered. There does not seem to be anything else I can have other than scans to see where it spreads and then more chemo……more scans more chemo ….

There has been no mention of chemo or targeted therapy. Is this realistic to be talking curative? Think I'm just starting to get anxious about treatment ending and no follow up for at least the next month. Thanks for reading and keep fighting 💪

I had urged her to put me on Truqap as a targeted therapy. She ordered it and it arrived on a Tuesday in Feb. She told me not to take it until she gave me permission which as not happened yet. Due to my pestering, it will happen very soon. She will prescribe it with Faslodex.

All well for a while then relapse so back on chemo and then on a drug targeted therapy called Rubraca, that's the short name for it. Was on and off it because of various things to do with my blood's but it was working until I got a bowel obstruction. Which is where I'm at, at the moment.

I was wondering if there is anyone on here that, like myself, is receiving targeted therapy with a drug called Tagrisso?

I'm having targeted therapy for lung cancer and have found it virtually impossible to go anywhere in the car without horrible nausea and vomiting. My GP prescribed very strong tablets that made me feel even worse but my Oncologist has since prescribed Metopimazine Venipharm for general sickness.

First-generation targeted therapy drugs outperformed traditional chemotherapy, but new mutations led to resistance. Researchers developed second and third-generation drugs to combat these resistant mutations.

ecd=mkm_ret_240724_mscpmrk_ophth_top-content_etid6690717&uac=150045MJ&impID=6690717 https://www.medscape.com/mtv/dry-eye/targeted-therapy?ecd=mkm_ret_240724_mscpmrk_ophth_top-content_etid6690717&uac=150045MJ&impID=6690717

The GIST tumors were shrinking out of site thanks to be taking Gleevec, a targeted therapy drug. My surgeon could not safely resect the HCC tumor so I am going to have the Y90 procedure. I am happy to have found this group and hope to learn from you.

https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer, an area traditionally overlooked because, from a therapeutic perspective, non-metastatic and metastatic tumor cells are often viewed

He thinks it is a small chance but if the results are positive can lead to a more targeted therapy. it will be approx 3 weeks before I get these test results. Till then he has started my father on Abiraterone. My worry is that in those three weeks the cancer may spread real fast.

PSA50 Responses to AR-Targeted Therapy Rechallenge: After progression on BAT, rechallenge with the prior AR-targeted therapy showed significantly better PSA50 responses in the post-enzalutamide cohort (68%) versus the post-abiraterone cohort (16%, p = 0.001)1.

The 2018 treatment guidelines, while informed by experts, are still pretty arbitrary and based primarily on pre genetics and pre targeted therapy experiences of those experts. These will change I think (or hope) in the next few years to better fit the risk stratification approach.