Interesting new targeted therapy trial - SHARE Metastatic ...

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Interesting new targeted therapy trial

Best521 profile image
8 Replies

I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment.

transcodetherapeutics.com

TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer, an area traditionally overlooked because, from a therapeutic perspective, non-metastatic and metastatic tumor cells are often viewed as being the same. However, despite significant efforts made in the past several years to decipher the genetic structure of primary tumors, there has been relatively limited attention given to comprehending the genetic makeup of metastatic tumors.

TTX-MC138 is hormone receptor independent and has the potential to treat metastatic breast cancer regardless of type (ER+/-, PR+/, HER2+/-, or combinations thereof)

So much to hopeful about!

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8 Replies
Merma profile image
Merma

This IS very exciting. Thank you for sharing!

love2golfwell profile image
love2golfwell

Thank you for sharing this. Sounds very promising!

Best521 profile image
Best521

I like how they focus on metastatic tumors and are not treating metastatic tumors as if they are the same as primary tumors. Even without science, intuitively as MBC patients we know our cancer is different.

mariootsi profile image
mariootsi

Good to know

Artesa profile image
Artesa

thank you!

diamags profile image
diamags

Thank you for sharing. When I was diagnosed, people asked what they could do for me and I always responded that they could send me articles such as this. Give me hope. The best gift.

CTGirl1962 profile image
CTGirl1962

This sounds freaking awesome!!! 🥳🥳🥳

YaY!! 🩷🩵💚

Best521 profile image
Best521

😄 Agree it is freakin awesome LOL I love how it is, tumor agnostic, which is one of the new directions in cancer treatments. I heard an interesting statistic during a cancer presentation, only 5% of cancer patients participate in trials. Many new cancer drugs never get to the FDA because they could not recruit enough patients for the trial. Many people wait until they are very ill before looking to join a trial and can’t qualify due to the severity of their condition. I knew my best hope was trials. I am currently in two trials and have done a total of three. My motto is early and often 😂. So far it has worked out very well. I am not standard issue and I went to a major cancer center because I didn’t want standard of care, I wanted the most cutting edge care. 🤞 Fingers crossed this company is able to deliver.

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Super interesting article

https://www.forbes.com/sites/victoriaforster/2018/06/04/new-immunotherapy-treatment-removes-all-tumo
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