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How is the second generation ADT like xtandi , zytiga etc decided ?
What determines which second line ADT will be given to whom ? I see there is zytiga , xtandi , nubeqa and others. Is it just left to the MO to decide ?
What determines which second line ADT will be given to whom ? I see there is zytiga , xtandi , nubeqa and others. Is it just left to the MO to decide ?
Tinkudi
in
Advanced Prostate Cancer
9 days ago
Does Decapeptyl ever just stop working?
Hello. I have an appointment in a couple of months with my gynae to review my treatment. I've been on Decapeptyl for two and a half years now, with low dose HRT to keep hot flushes etc at bay. I had a lap about 18 months ago. I do have occasional pain but nowhere near as bad as it was pre-lap and pre-injection
Hello. I have an appointment in a couple of months with my gynae to review my treatment. I've been on Decapeptyl for two and a half years now, with low dose HRT to keep hot flushes etc at bay. I had a lap about 18 months ago. I do have occasional pain but nowhere near as bad as it was pre-lap and pre-injection
atealdeer
in
Endometriosis UK
9 days ago
Pelvic pain back 3 months after Hysterectomy
I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was hard to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put on Prostap and add back hrt. The Prostap
I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was hard to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put on Prostap and add back hrt. The Prostap
Mindfullness4791
in
Endometriosis UK
10 days ago
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Original pelvic pain back 3 months after hysterectomy
To cut a very long story short. I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was difficult to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put
To cut a very long story short. I have had significant pelvic pain with bowel and bladder issues for 2.5 years. It was difficult to get a diagnosis. I was told at first it was a bowel issue, then Endometriosis/Adenomyosis and was eventually diagnosed with 4 fibroids, 1 being 7cm. A year ago, I was put
Mindfullness4791
in
Pelvic Pain Support Network
10 days ago
How do I gradually run faster, what’s best?
I need to go to go out & do Wk 8 Run 2 this morning & prevaricating (but will do it) …. I’m an exceptionally slow runner and run 1 on Wednesday felt rubbish, so was good to read about Toxic 10 & Tomato Ten in someone else’s post as I do have these! (And in swimming too!) I want to run gradually faster
I need to go to go out & do Wk 8 Run 2 this morning & prevaricating (but will do it) …. I’m an exceptionally slow runner and run 1 on Wednesday felt rubbish, so was good to read about Toxic 10 & Tomato Ten in someone else’s post as I do have these! (And in swimming too!) I want to run gradually faster
Snippit
Graduate
in
Couch to 5K
10 days ago
Using Red Clover, Sage and Ashwagandha for the menopause, and it's safety with hypothyroidism?
Hiya. I am currently in the menopause with early onset osteoporosis, and have autoimmune related hypothyroidism. I am looking into various ways to manage this, conventional HRT being the least desirable. I much prefer natural ways to manage my health wherever possible, and I've found various herbal supplements
Hiya. I am currently in the menopause with early onset osteoporosis, and have autoimmune related hypothyroidism. I am looking into various ways to manage this, conventional HRT being the least desirable. I much prefer natural ways to manage my health wherever possible, and I've found various herbal supplements
MindfulMoments
in
Thyroid UK
10 days ago
Pick and mitch advice.
My hormones have been leveled out now for 1.5 years since I got my depo provera sorted. But my smacking head ache that comes on when the progesterone drops came back for one day before my last injection and disappeared in hours after the injection was done.My new shifts at my job mean I'm going to be
My hormones have been leveled out now for 1.5 years since I got my depo provera sorted. But my smacking head ache that comes on when the progesterone drops came back for one day before my last injection and disappeared in hours after the injection was done.My new shifts at my job mean I'm going to be
SavageGold
in
Endometriosis UK
10 days ago
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism.....a study
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism
https://academic.oup.com/jcem/article/106/11/e4400/6311304 [u]
The rationale behind thyroid hormone replacement therapy is to administer thyroid hormone in a way that restores
Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism
https://academic.oup.com/jcem/article/106/11/e4400/6311304 [u]
The rationale behind thyroid hormone replacement therapy is to administer thyroid hormone in a way that restores
DippyDame
in
Thyroid UK
11 days ago
Early breast cancer
I've just been diagnosed with early breast cancer. I've had mammogram, biopsy and mri. The lump is 3cm. I am awaiting a tests on my lymph nodes. Then have been told lumpectomy, radiotherapy and /or chemotherapy. It's oestrogen and progesterone driven. I am on hrt, I'm perimenopausal. I also had a heart
I've just been diagnosed with early breast cancer. I've had mammogram, biopsy and mri. The lump is 3cm. I am awaiting a tests on my lymph nodes. Then have been told lumpectomy, radiotherapy and /or chemotherapy. It's oestrogen and progesterone driven. I am on hrt, I'm perimenopausal. I also had a heart
Duvetdays15
in
My Breast Cancer Community
11 days ago
apalutamide vs. abiraterone
My husband has been recommended ADT + abiraterone + prednisone for two years. My friend who is an oncologist suggested apalutamide instead as it doesn't need to be supplements with prednisone and has less side effects. Wanted your opinion.
My husband has been recommended ADT + abiraterone + prednisone for two years. My friend who is an oncologist suggested apalutamide instead as it doesn't need to be supplements with prednisone and has less side effects. Wanted your opinion.
SherryKahn
in
Advanced Prostate Cancer
12 days ago
SUV-Max
Hello , Ive been on Eligard , Zytiga , predizone 26 months . Im oligo with 1 tumor in pelvic lymph node that was radiated , then 25 fractions across the pelvic region . The tumor they radiated was at SUV-MAX 24 . All labs are good , not much of side effects . I thought about stopping the meds after
Hello , Ive been on Eligard , Zytiga , predizone 26 months . Im oligo with 1 tumor in pelvic lymph node that was radiated , then 25 fractions across the pelvic region . The tumor they radiated was at SUV-MAX 24 . All labs are good , not much of side effects . I thought about stopping the meds after
reconjj
in
Advanced Prostate Cancer
13 days ago
HRT post ovarian cancer
Hi, does anyone have anything on HRT post ovarian cancer and radical hysterectomy? I’m 14 years post diagnosis and struggling with brain fog and fatigue. Is HRT an option?
Hi, does anyone have anything on HRT post ovarian cancer and radical hysterectomy? I’m 14 years post diagnosis and struggling with brain fog and fatigue. Is HRT an option?
ruthc
in
My Ovacome
13 days ago
Dad 2nd BCR. Advice needed...
After a very late salvage radiation + 1 year Lupron. He has been off ADT for 1 year when PSA began to rise again. From 0.01 to 0.03 in less than 2 months then 0.05 after another 3 months. Is this indicative of an aggressive progression and metastasis? The oncologist said that the doubling time is not
After a very late salvage radiation + 1 year Lupron. He has been off ADT for 1 year when PSA began to rise again. From 0.01 to 0.03 in less than 2 months then 0.05 after another 3 months. Is this indicative of an aggressive progression and metastasis? The oncologist said that the doubling time is not
MsBoBo
in
Advanced Prostate Cancer
13 days ago
Menopause really sucks!!!
I am almost 51 & being absolutely battered by the perimenopause.i started running in my 40's in 2018 & absolutely loved it...I got so much from it.i have done C25K several times since then.in 2022 I injured myself...caused by the stupid lack of hormones & had to stop for 18 months.started HRT in March
I am almost 51 & being absolutely battered by the perimenopause.i started running in my 40's in 2018 & absolutely loved it...I got so much from it.i have done C25K several times since then.in 2022 I injured myself...caused by the stupid lack of hormones & had to stop for 18 months.started HRT in March
Notsonifty50
in
Menopause and Perimenopause Support
13 days ago
Here I am again!!!😳
I am almost 51 & being absolutely battered by the perimenopause.i started running in my 40's in 2018 & absolutely loved it...I got so much from it.i have done C25K several times since then.in 2022 I injured myself...caused by the stupid lack of hormones & had to stop for 18 months.started HRT in March
I am almost 51 & being absolutely battered by the perimenopause.i started running in my 40's in 2018 & absolutely loved it...I got so much from it.i have done C25K several times since then.in 2022 I injured myself...caused by the stupid lack of hormones & had to stop for 18 months.started HRT in March
Notsonifty50
in
Couch to 5K
13 days ago
5 aRIs and PCa and recurrence.
I’m recurrent in prostate bed with three negative PSMA PET scans and essentially unchanged size of enhancing nodule over 18 months on three MRIs DUT and FIN began when PSA reached 0.36. In six weeks dropped to 0.26 after beginning DUT and FIN. they are affecting sensitivity of the PSMA scans. After
I’m recurrent in prostate bed with three negative PSMA PET scans and essentially unchanged size of enhancing nodule over 18 months on three MRIs DUT and FIN began when PSA reached 0.36. In six weeks dropped to 0.26 after beginning DUT and FIN. they are affecting sensitivity of the PSMA scans. After
LowT
in
Advanced Prostate Cancer
13 days ago
Hypo, HRT and weight gain?
Hi. Have people who are hypo and use HRT gained weight since starting it? Everything I read re HRT, claims it can cause weight gain, which to a Hypo/Hashi sufferer, this is the last thing you want to hear. What have been people's experience? Thanks, appreciate it.
Hi. Have people who are hypo and use HRT gained weight since starting it? Everything I read re HRT, claims it can cause weight gain, which to a Hypo/Hashi sufferer, this is the last thing you want to hear. What have been people's experience? Thanks, appreciate it.
MindfulMoments
in
Thyroid UK
14 days ago
Methylation to feel good
Hi Folks, Thank you for all the advice and words of encouragement. I’ve been reading a lot of papers on methylation and the effects on the body, below is an article that seems to sum it up if interested… https://draxe.com/health/methylation/ I’ve also been doing a lot of reading on higher incidences
Hi Folks, Thank you for all the advice and words of encouragement. I’ve been reading a lot of papers on methylation and the effects on the body, below is an article that seems to sum it up if interested… https://draxe.com/health/methylation/ I’ve also been doing a lot of reading on higher incidences
Karenedawson
in
Pernicious Anaemia Society
14 days ago
Coming Off Ropinirol
Hello RLS Community First off, I just want to thank so many of you for the amazing support you offer here. It’s not hyperbolic of me to say you are LIFE SAVERS. I really appreciate the feedback and responses I had to my previous post. 🙏💕🙏 On to my question: I would like to come off Ropinirol
Hello RLS Community First off, I just want to thank so many of you for the amazing support you offer here. It’s not hyperbolic of me to say you are LIFE SAVERS. I really appreciate the feedback and responses I had to my previous post. 🙏💕🙏 On to my question: I would like to come off Ropinirol
Chocolate123Lab
in
Restless Legs Syndrome
14 days ago
is this what CR looks like?
Starting Nov 20 last year, I began a relugolix on-cycle. Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder
Starting Nov 20 last year, I began a relugolix on-cycle. Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder
lokibear0803
in
Advanced Prostate Cancer
14 days ago
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