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Stage 4 A Prostate cancer
My partner was diagnosed with stage 4 A prostate cancer with spread to pelvic lymph nodes. Oncologist has recommended surgery followed by radiation and hormone therapy for a good prognosis. He is 65 healthy and no symptoms. PSA was 11. Has a history of prostrate cancer. Was wondering if we should get
My partner was diagnosed with stage 4 A prostate cancer with spread to pelvic lymph nodes. Oncologist has recommended surgery followed by radiation and hormone therapy for a good prognosis. He is 65 healthy and no symptoms. PSA was 11. Has a history of prostrate cancer. Was wondering if we should get
SherryKahn
in
Advanced Prostate Cancer
4 months ago
helpful article
Sznurkowski JJ. To Bev or Not to Bev during Ovarian Cancer Maintenance Therapy? Cancers (Basel). 2023 May 30;15(11):2980. doi: 10.3390/cancers15112980. PMID: 37296941; PMCID: PMC10251846. I feel people are often wondering why they can’t have Avastin or PARPs again and this article gives good scientific
Sznurkowski JJ. To Bev or Not to Bev during Ovarian Cancer Maintenance Therapy? Cancers (Basel). 2023 May 30;15(11):2980. doi: 10.3390/cancers15112980. PMID: 37296941; PMCID: PMC10251846. I feel people are often wondering why they can’t have Avastin or PARPs again and this article gives good scientific
delia2
in
My Ovacome
4 months ago
Getting head around what to expect
I like to have facts. In times of stress I think Facts are our friend. Better to be prepared, mentally, physically, financially, with support systems, etc.. so looking for any insights as to what I should expect and prepare my husband, myself and my kids/family for in the weeks and months, years ahead
I like to have facts. In times of stress I think Facts are our friend. Better to be prepared, mentally, physically, financially, with support systems, etc.. so looking for any insights as to what I should expect and prepare my husband, myself and my kids/family for in the weeks and months, years ahead
Melzer2169
in
Advanced Prostate Cancer
4 months ago
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Assessing the Benefit of CAR T-cell Therapies for mCRPC
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
A first-in-human phase 1 trial (NCT03873805) investigated the safety and bioactivity of prostate stem cell antigen-directed CAR T cells for patients with metastatic castration-resistant prostate cancer. CancerNetwork® spoke with Saul Priceman, PhD, associate professor and associate director of the
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
Elahere
After 4+ years of successful treatment with Carboplatin for metastatic ovarian cancer the carbo has stopped working. This week I will start a brand new drug called Elahere that was just given full approval in the U.S. on March 22. I am excited but also scared since one of the serious potential side
After 4+ years of successful treatment with Carboplatin for metastatic ovarian cancer the carbo has stopped working. This week I will start a brand new drug called Elahere that was just given full approval in the U.S. on March 22. I am excited but also scared since one of the serious potential side
Why4300
in
My Ovacome
4 months ago
ESMO 2024: Cabozantinib plus Atezolizumab versus 2nd novel hormonal therapy inmetastatic CRPC, overall survival results of CONTACT-02 Study
Basically, even if there was a prolonged progression-free survival, OS was not statistically different in the two arms. BUT a strong survival advantage was seen in patients with liver metastasis! https://www.urotoday.com/conference-highlights/esmo-2024/esmo-2024-prostate-cancer/154863-esmo-2024-cabozantinib-plus-atezolizumab-versus
Basically, even if there was a prolonged progression-free survival, OS was not statistically different in the two arms. BUT a strong survival advantage was seen in patients with liver metastasis! https://www.urotoday.com/conference-highlights/esmo-2024/esmo-2024-prostate-cancer/154863-esmo-2024-cabozantinib-plus-atezolizumab-versus
Maxone73
in
Advanced Prostate Cancer
7 hours ago
Generative AI tool to help with immunohistochemistry
This is a very interesting system! Thanks to Justfor_ for sending me the references. In cancer research, staining involves coloring tissues to highlight specific features under a microscope. Common techniques like H&E staining help visualize the general structure, while immunohistochemistry (IHC)
This is a very interesting system! Thanks to Justfor_ for sending me the references. In cancer research, staining involves coloring tissues to highlight specific features under a microscope. Common techniques like H&E staining help visualize the general structure, while immunohistochemistry (IHC)
Maxone73
in
Advanced Prostate Cancer
19 hours ago
heading for salvage therapy
hello all. Well my last two ( three month) PSA tests were 0.10 and MO. And RO. Recommend somewhat early salvage radiation treatment. A question I would like some input on is should I look into proton therapy over IMRT. I would need to travel to Fred hutch or Salt Lake City as I live in Reno Nv. Just
hello all. Well my last two ( three month) PSA tests were 0.10 and MO. And RO. Recommend somewhat early salvage radiation treatment. A question I would like some input on is should I look into proton therapy over IMRT. I would need to travel to Fred hutch or Salt Lake City as I live in Reno Nv. Just
Elkguide
in
Advanced Prostate Cancer
5 days ago
When did you feel some hope you might pull out of this and not die next week?
New diagnosis. What i thought was back pain just turned out to be Advanced Metastatic PROSTATE Cancer on a CT Scan with contrast and PSA of 56. I've been blessed with excellent health til now. This is all scary NEW to me and my wife, we are in shock. Oncologist/Urologist ordered a ultrasound guided
New diagnosis. What i thought was back pain just turned out to be Advanced Metastatic PROSTATE Cancer on a CT Scan with contrast and PSA of 56. I've been blessed with excellent health til now. This is all scary NEW to me and my wife, we are in shock. Oncologist/Urologist ordered a ultrasound guided
ELOfan
in
Advanced Prostate Cancer
5 days ago
In vivo/vitro latest immunotherapy proof of concept by targeting IL30 in prostate cancer
Meanwhile in Italy, a group of researchers....this study discusses the development of immunoliposome-based CRISPR/Cas9 delivery targeting IL30 in prostate cancer. In vivo and in vitro it showed great results in inhibiting tumor growth and metastasis formation. Alteration of tumor environment (reduced
Meanwhile in Italy, a group of researchers....this study discusses the development of immunoliposome-based CRISPR/Cas9 delivery targeting IL30 in prostate cancer. In vivo and in vitro it showed great results in inhibiting tumor growth and metastasis formation. Alteration of tumor environment (reduced
Maxone73
in
Advanced Prostate Cancer
5 days ago
Seeking Advice on Clinical Trials or Treatments for Advanced Prostate Cancer with Bone Marrow Involvement
Dear Forum Members, I am reaching out for guidance and support regarding my father’s ongoing battle with advanced prostate cancer. About a year ago, he was diagnosed with stage 4 prostate cancer with extensive bone metastases but no organ involvement. Recently, we discovered that he has a BRCA2 mutation
Dear Forum Members, I am reaching out for guidance and support regarding my father’s ongoing battle with advanced prostate cancer. About a year ago, he was diagnosed with stage 4 prostate cancer with extensive bone metastases but no organ involvement. Recently, we discovered that he has a BRCA2 mutation
Fightingformyfather
in
Advanced Prostate Cancer
6 days ago
PSA from .08 to 2.1, after 2yrs ADT with zytiga and RT @59 yr
so seems to be back and waiting on PSMA PER SCAN. From what I understand, they usually look for something and do a scavenge RT treatment. Anyone who’s gone through this did you have to go back on ADT because that just sucks.. I had high risk Gleason score 9 anybody deal with this? I’m sure. Let me know
so seems to be back and waiting on PSMA PER SCAN. From what I understand, they usually look for something and do a scavenge RT treatment. Anyone who’s gone through this did you have to go back on ADT because that just sucks.. I had high risk Gleason score 9 anybody deal with this? I’m sure. Let me know
Eieio
in
Advanced Prostate Cancer
4 months ago
Gingko Biloba - Supplement Advice
Hello everyone, I'm reaching out for advice on using Ginkgo Biloba to combat brain fog. My previous experience with the Amitamin Ginkgo complex yielded promising results in boosting mental clarity. However, I've noticed it contains iodine (150ug), which I'd rather steer clear of. With that in mind
Hello everyone, I'm reaching out for advice on using Ginkgo Biloba to combat brain fog. My previous experience with the Amitamin Ginkgo complex yielded promising results in boosting mental clarity. However, I've noticed it contains iodine (150ug), which I'd rather steer clear of. With that in mind
BookLover2020
in
Thyroid UK
4 months ago
Scared
Hi, I’m one month post op, Ivor Lewis I spent 9 days in CCD and 5 on the ward. At home now and struggling to eat due to no appetite and not feeling hungry. I’ve lost quite a lot of weight and hate the way I look. All skin and bone. I am scared of the post op Chemotherapy as I struggled before hand, only
Hi, I’m one month post op, Ivor Lewis I spent 9 days in CCD and 5 on the ward. At home now and struggling to eat due to no appetite and not feeling hungry. I’ve lost quite a lot of weight and hate the way I look. All skin and bone. I am scared of the post op Chemotherapy as I struggled before hand, only
Myfrenchieboy
in
Oesophageal & Gastric Cancer
9 days ago
WHAT SHOULD I AVOID TAKING WITH IBRANCE
I am a Nigerian ,a single lady of 32years ,I was diagnosed of metastatic breast cancer on September 2023 then I redid my biopsy for a second opinion and it was same ,so I underwent 8chemo of Paclitaxel and carboplatin, which was 3weeks regimen from October 2023 to March 2023 ,afterwards a chest CT was
I am a Nigerian ,a single lady of 32years ,I was diagnosed of metastatic breast cancer on September 2023 then I redid my biopsy for a second opinion and it was same ,so I underwent 8chemo of Paclitaxel and carboplatin, which was 3weeks regimen from October 2023 to March 2023 ,afterwards a chest CT was
RuchiM
in
SHARE Metastatic Breast Cancer
4 months ago
after being fast tracked ABD-147 was designed orphan drug for the Treatment of Neuroendocrine Carcinoma (prostate included)
DLL3 is expressed by neuroendocrine cancers, including prostate cancer! They plan to start a phase 1 trial by the end of 2024 (on lung cancer, but it’s worth to keep an eye on it). “ABD-147 is a next-generation precision radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225Ac)
DLL3 is expressed by neuroendocrine cancers, including prostate cancer! They plan to start a phase 1 trial by the end of 2024 (on lung cancer, but it’s worth to keep an eye on it). “ABD-147 is a next-generation precision radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225Ac)
Maxone73
in
Advanced Prostate Cancer
11 days ago
Aussies will save us all: from Oz, a molecule that can (could) treat resistant prostate cancer
They will need some time still...but... "CDKI-73 is currently being investigated in Phase 2 clinical trials in patients with relapsed and therapy-resistant acute myeloid leukaemia, an aggressive blood cancer." Which means that at least we would not have to wait for a phase 1 to tell us the therapeutic
They will need some time still...but... "CDKI-73 is currently being investigated in Phase 2 clinical trials in patients with relapsed and therapy-resistant acute myeloid leukaemia, an aggressive blood cancer." Which means that at least we would not have to wait for a phase 1 to tell us the therapeutic
Maxone73
in
Advanced Prostate Cancer
15 days ago
Pulmonary Complications Post Lutetium-177-PSMA-617 Therapy in Metastatic Castration-Resistant Prostate Cancer #Pluvicto
We present the case of a patient with heavily pretreated metastatic castration-resistant prostate cancer (mCRPC) who underwent treatment with lutetium Lu-177 vipivotide tetraxetan (also known as 177Lu-PSMA-617) due to progressive disease despite multiple lines of therapy, including chemotherapy, hormonal
We present the case of a patient with heavily pretreated metastatic castration-resistant prostate cancer (mCRPC) who underwent treatment with lutetium Lu-177 vipivotide tetraxetan (also known as 177Lu-PSMA-617) due to progressive disease despite multiple lines of therapy, including chemotherapy, hormonal
God_Loves_Me
in
Advanced Prostate Cancer
4 months ago
Is Curcumin Another "Double-Edged Sword" In The Fight Against Prostate Cancer?" Still spinning my head trying to figure it out.
Many in-vitro and in-vivo studies point to antiproliferative, antimetastatic, anti-inflammatory, anti-invasive, etc. properties that Curcumin have against prostate cancer cells. But the compound is also regarded as a significant booster of Testosterone, which is a major driver of androgen-sensitive
Many in-vitro and in-vivo studies point to antiproliferative, antimetastatic, anti-inflammatory, anti-invasive, etc. properties that Curcumin have against prostate cancer cells. But the compound is also regarded as a significant booster of Testosterone, which is a major driver of androgen-sensitive
back2health
in
Advanced Prostate Cancer
18 days ago
A question about radiation resistance
Last week a post was made about Decipher showing high radiation resistance. My decipher showed the same. Quick question. If you have had SBRT and it hasn't deliver a “killing dose” to tumor, is brachytherapy a follow up option? My PSA showed rise after SBRT, (from 8.6 to 12) Ro and Mo attributed
Last week a post was made about Decipher showing high radiation resistance. My decipher showed the same. Quick question. If you have had SBRT and it hasn't deliver a “killing dose” to tumor, is brachytherapy a follow up option? My PSA showed rise after SBRT, (from 8.6 to 12) Ro and Mo attributed
Chasbearcat999
in
Prostate Cancer Network
4 months ago
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