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school anxiety
I’m in speech therapy grad school, something I’ve worked towards for a VERY long time. I made so many sacrifices to be here and I got a C in a clinical experience. In my program you have to get a B to pass and move forward. I have to redo this clinical experience and any time I have a meeting for it
I’m in speech therapy grad school, something I’ve worked towards for a VERY long time. I made so many sacrifices to be here and I got a C in a clinical experience. In my program you have to get a B to pass and move forward. I have to redo this clinical experience and any time I have a meeting for it
Pupsandpeonies
in
Anxiety and Depression Support
2 months ago
Supporting evidence for PIP
I’m ploughing through the online form and it keeps saying about supporting evidence. I was diagnosed in 2021 by my then GP in the midlands over the Covid period - so not many doctor visits. Not much prescribed, using paracetamol and/or ibuprofen as and when necessary. Basically have been self-managing
I’m ploughing through the online form and it keeps saying about supporting evidence. I was diagnosed in 2021 by my then GP in the midlands over the Covid period - so not many doctor visits. Not much prescribed, using paracetamol and/or ibuprofen as and when necessary. Basically have been self-managing
Gulfstream_Maggie
in
Fibromyalgia Action UK
2 months ago
List of good Genetic Tests in Homologous Recombination Deficiency in PCa and the Mechanisms of Resistance to PARP Inhibitors
I was searching RAD50 and PARPinhibitors and since i am going for a high risk genetic consult i came across this good explanation of different genetic testing. Title of article:
Homologous Recombination Deficiency in Ovarian, Breast, Colorectal, Pancreatic, Non-Small Cell Lung and Prostate Cancers
I was searching RAD50 and PARPinhibitors and since i am going for a high risk genetic consult i came across this good explanation of different genetic testing. Title of article:
Homologous Recombination Deficiency in Ovarian, Breast, Colorectal, Pancreatic, Non-Small Cell Lung and Prostate Cancers
KocoPr
in
Advanced Prostate Cancer
2 months ago
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Zolodex and HRT
hi there, my diagnosis is very new and I’ve just had my first zolodex injection this afternoon. I was also given HRT patches containing oestrogen which I’ve put on. But I’m confused as the zolodex surely stoped oestrogen production so why have I been put on patches that give it back? Surely it will counteract
hi there, my diagnosis is very new and I’ve just had my first zolodex injection this afternoon. I was also given HRT patches containing oestrogen which I’ve put on. But I’m confused as the zolodex surely stoped oestrogen production so why have I been put on patches that give it back? Surely it will counteract
Chronsandadenomysois
in
Adenomyosis Advice Association
9 months ago
25th Park Run!
It may not seem like a big deal but it is to me. I couldn't walk til I was 4, have had 3 hip replacements and back surgery. I never ran before I was 69 and now I've done 25 Park runs. I'm feeling very proud of myself. I even knocked a minute off last week's time! It was a glorious morning. I just took
It may not seem like a big deal but it is to me. I couldn't walk til I was 4, have had 3 hip replacements and back surgery. I never ran before I was 69 and now I've done 25 Park runs. I'm feeling very proud of myself. I even knocked a minute off last week's time! It was a glorious morning. I just took
Bruch1
Graduate
in
Couch to 5K
6 months ago
BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
How to convince your GP a suppressed TSH is ok?
For years I’ve had a suppressed TSH following a trial of T3 probably 5 years ago which didn’t work and I haven’t taken it for around 4 years (need to check my records for exact dates). My GP has always been fine with it, and even the rubbish NHS endo agreed it would take time to recover - or as I know
For years I’ve had a suppressed TSH following a trial of T3 probably 5 years ago which didn’t work and I haven’t taken it for around 4 years (need to check my records for exact dates). My GP has always been fine with it, and even the rubbish NHS endo agreed it would take time to recover - or as I know
CornishChick
in
Thyroid UK
9 months ago
Low cortisol but within normal nhs range
I have had 2 blood cortisol tests at 9am 1st one was 133 nmol/L and the 2nd one was 233 nmol/L . I asked to have a short synacten test to see if my pituitary is failing ( hypopituitarism) , as one of my big symptoms is low motivation, tiredness, hypothyroidism and zero libido for years despite being
I have had 2 blood cortisol tests at 9am 1st one was 133 nmol/L and the 2nd one was 233 nmol/L . I asked to have a short synacten test to see if my pituitary is failing ( hypopituitarism) , as one of my big symptoms is low motivation, tiredness, hypothyroidism and zero libido for years despite being
minus
in
Thyroid UK
9 months ago
Thank you Angela for sharing your story!
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
SkcinHQ
Partner
in
Skin Cancer UK
2 months ago
Side effects on combination therapy : thyroxine and T3
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
TheaW
in
Thyroid UK
2 months ago
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
constipation leading to Pelvic Floor dysfunction
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
Profound15
in
IBS Network
2 months ago
Enemas for constipation
I am taking flecainide and bisoprolol for my afib. The medication is doing fine but I’ve got what I believe to be Pelvic Floor dysfunction. Basically one of my rectum muscles (at exit) is contracting when it should be relaxing. I’ve got biofeedback physio on Monday but wanted to know if anyone has experience
I am taking flecainide and bisoprolol for my afib. The medication is doing fine but I’ve got what I believe to be Pelvic Floor dysfunction. Basically one of my rectum muscles (at exit) is contracting when it should be relaxing. I’ve got biofeedback physio on Monday but wanted to know if anyone has experience
Profound15
in
Atrial Fibrillation Support
2 months ago
Hashimotos?
I have had elevated TSH for about 10 years and my GP did not seem very keen to do anything. I got a monitor my health test on the 12/9/23 and advanced thyroid check with Medichecks on the 11/10/23. The results are below and I would really appreciate any support. I have booked an appointment with one
I have had elevated TSH for about 10 years and my GP did not seem very keen to do anything. I got a monitor my health test on the 12/9/23 and advanced thyroid check with Medichecks on the 11/10/23. The results are below and I would really appreciate any support. I have booked an appointment with one
Susanmcg
in
Thyroid UK
9 months ago
Mild aortic stenosis...is this normal?
A heart mumur was picked up when I was at the a&e back in June. Had an echocardiogram done September. Finally after trying to chase the a&e cardiologist who checked the echocardiogram he said my results were all normal. So I requested my results to check for myself as I feel rotten daily and it's says
A heart mumur was picked up when I was at the a&e back in June. Had an echocardiogram done September. Finally after trying to chase the a&e cardiologist who checked the echocardiogram he said my results were all normal. So I requested my results to check for myself as I feel rotten daily and it's says
Charts
in
Hughes Syndrome APS Forum
10 months ago
Interesting new targeted therapy trial
I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment. https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer,
I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment. https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer,
Best521
in
SHARE Metastatic Breast Cancer
2 months ago
InkMune clinical trial goes on: second cohort is being treated
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
Maxone73
in
Advanced Prostate Cancer
2 months ago
Holistic POSITIVE results
Hello, I was dx with PD in 2019. I’ve progressed to stage 3 and have tried a lot of synthetic meds. I wont take tgem if the side effects worsen my current symptoms. That excludes most. I have read a million articles on new and upcoming tests and trials. I’m tired of chasing the rabbit. Although I cant
Hello, I was dx with PD in 2019. I’ve progressed to stage 3 and have tried a lot of synthetic meds. I wont take tgem if the side effects worsen my current symptoms. That excludes most. I have read a million articles on new and upcoming tests and trials. I’m tired of chasing the rabbit. Although I cant
GigiOf8
in
Cure Parkinson's
2 months ago
advice please
hi everyone . Here’s my story so far .. haven’t been ‘right’ since May 2021 . First symptoms were hair loss and tiredness. I contacted the GP who did my bloods and said my thyroid was slightly low and wanted to recheck in 8 weeks T4 = 10.4 and TSH 0-8 So they rechecked in july 22 and said again
hi everyone . Here’s my story so far .. haven’t been ‘right’ since May 2021 . First symptoms were hair loss and tiredness. I contacted the GP who did my bloods and said my thyroid was slightly low and wanted to recheck in 8 weeks T4 = 10.4 and TSH 0-8 So they rechecked in july 22 and said again
Jacksondog
in
Thyroid UK
9 months ago
Question re:periods
Hello everyone, Up until I started Levo in May this year I was having regular periods every 4 weeks. I think it was my own cycle rather than just an hrt “withdrawal bleed” from my hrt, as the periods were very heavy each time and lasted about 7 days. I had spells of missing a couple of periods here
Hello everyone, Up until I started Levo in May this year I was having regular periods every 4 weeks. I think it was my own cycle rather than just an hrt “withdrawal bleed” from my hrt, as the periods were very heavy each time and lasted about 7 days. I had spells of missing a couple of periods here
JoJoloveschocolate
in
Thyroid UK
9 months ago
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