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Experiences with
Prostate-specific antigen (PSA)
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Making a Case for Intermittent ADT in Metastatic Hormone Sensitive Prostate Cancer
PSA
was less than or equal to 4 ng/ml.
PSA
was less than or equal to 4 ng/ml.
NPfisherman
in
Fight Prostate Cancer
3 months ago
psa increasing scans stable
Does anyone else have
PSA
increasing but scans are stable- if so when do you think it's time To switch meds if your scans are every three months and stable and your feeling fine - and all other bloodwork is fine? Do you stay the course and go by scans and symptoms?
Does anyone else have
PSA
increasing but scans are stable- if so when do you think it's time To switch meds if your scans are every three months and stable and your feeling fine - and all other bloodwork is fine? Do you stay the course and go by scans and symptoms?
Chris52981
in
Advanced Prostate Cancer
7 months ago
PSA Survival vs Testosterone Nadir - 2
This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20
This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20
janebob99
in
Advanced Prostate Cancer
6 months ago
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PSA Survival vs Testosterone Nadir - 1
This plot shows the Biochemical Relapse Free Survival after RT and ADT, versus time for up to 18 years, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone
This plot shows the Biochemical Relapse Free Survival after RT and ADT, versus time for up to 18 years, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone
janebob99
in
Advanced Prostate Cancer
6 months ago
Pluvicto damaging salivary glands?
Now on ADT holiday since 1-1-24,
psa
unmeasurable so far. During the treatment, had increasingly serious drymouth and nasal congestion and irritation with bleeding, which I attributed to radiation damage. Since then, there has been some, slow improvement, but still not right yet.
Now on ADT holiday since 1-1-24,
psa
unmeasurable so far. During the treatment, had increasingly serious drymouth and nasal congestion and irritation with bleeding, which I attributed to radiation damage. Since then, there has been some, slow improvement, but still not right yet.
Kayakbob
in
Advanced Prostate Cancer
4 months ago
SRBT and EXTEND trial
They only evaluated "progression-free survival" which, at 22 months, was almost entirely lack of
PSA
progression. They claimed that the lack of
PSA
progression made it safe to give patients a break from ADT".
They only evaluated "progression-free survival" which, at 22 months, was almost entirely lack of
PSA
progression. They claimed that the lack of
PSA
progression made it safe to give patients a break from ADT".
Purple-Bike
in
Advanced Prostate Cancer
7 months ago
Started Xtandi and AST spiked!
Started on Zytiga last year but had to stop due to elevated liver enzymes, so I switched to Casodex about two months ago, but
PSA
numbers started to climb from 0.1 to almost 0.3 within about 3 months.
Started on Zytiga last year but had to stop due to elevated liver enzymes, so I switched to Casodex about two months ago, but
PSA
numbers started to climb from 0.1 to almost 0.3 within about 3 months.
CoastalTex
in
Advanced Prostate Cancer
16 days ago
Update for alperk
PSA
following 4/4/24 radiation has climbed from 5/8-3.46,6/3-5.88,7/3-8.09,7/29-15.53(wow!). I start docetaxel 8/5 every 2 weeks for 6 months. I read that the 2 week dosage is appropriate for older, frail men. Since I am 83, I expect this is why my MO chose this.
PSA
following 4/4/24 radiation has climbed from 5/8-3.46,6/3-5.88,7/3-8.09,7/29-15.53(wow!). I start docetaxel 8/5 every 2 weeks for 6 months. I read that the 2 week dosage is appropriate for older, frail men. Since I am 83, I expect this is why my MO chose this.
alperk
in
Advanced Prostate Cancer
17 days ago
Low PSA + high Gleason-FYI
For instance, I had an initial
PSA
of 4.8 (4.6 after retesting), and I’m Gleason 9. Three of my doctors have mentioned it to me in passing (most recently today), which led me to Google it.
For instance, I had an initial
PSA
of 4.8 (4.6 after retesting), and I’m Gleason 9. Three of my doctors have mentioned it to me in passing (most recently today), which led me to Google it.
Jpburns
in
Advanced Prostate Cancer
7 months ago
3 month PSA post RT/ADT, low enough?
Am I jumping the gun or should I be concerned that this almost three month follow up
PSA
isn’t low enough? I’m tolerating ADT pretty well so I’m not opposed to extending the duration if necessary.
Am I jumping the gun or should I be concerned that this almost three month follow up
PSA
isn’t low enough? I’m tolerating ADT pretty well so I’m not opposed to extending the duration if necessary.
sptill72
in
Prostate Cancer Network
7 months ago
Stage 4, GL 9 seeking advice
My blood work is good:
PSA
0.95 down from 70 and every other marker is green. Where do I go from here? My Gleason 4 plus 5, which is a little better than 5 plus 4. The cancer is literally all over -- multiple sites.
My blood work is good:
PSA
0.95 down from 70 and every other marker is green. Where do I go from here? My Gleason 4 plus 5, which is a little better than 5 plus 4. The cancer is literally all over -- multiple sites.
Poollover
in
Advanced Prostate Cancer
3 months ago
Anyone out there start Pluvicto at 85 or older?…Oncologist wants me to try but I’m Hesitant due to side effects possible…
months of BAT…He says I’ll tolerate it good and if not we can just quit….I know you just can’t quit and in 3 days the Pluvicto is gone…At this stage (I’m 86 in a week) I don’t think I could recover from possible Pluvicto side effects….I want to go with BAT again using either zytega or Xtandi to get my
PSA
months of BAT…He says I’ll tolerate it good and if not we can just quit….I know you just can’t quit and in 3 days the Pluvicto is gone…At this stage (I’m 86 in a week) I don’t think I could recover from possible Pluvicto side effects….I want to go with BAT again using either zytega or Xtandi to get my
PSA
Roxysdad
in
Advanced Prostate Cancer
2 months ago
herbicide and recurrence
It's been almost 4 years since I completed salvage radiation and my
PSA
has been .03 for a while. Things are looking good for me and I'd like to keep it that way. Thanks for the help. Best wishes to all.
It's been almost 4 years since I completed salvage radiation and my
PSA
has been .03 for a while. Things are looking good for me and I'd like to keep it that way. Thanks for the help. Best wishes to all.
mistersafety
in
Advanced Prostate Cancer
4 months ago
18F-flotufolastat PET alters treatment approach for nearly 90% of patients with recurrent prostate cancer
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer metastasis who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated
PSA
levels."
"18F-flotufolastat is approved by the FDA for use in patients with suspected prostate cancer metastasis who are potentially curable by definitive surgery or radiation, and patients with suspected prostate cancer recurrence based on elevated
PSA
levels."
Maxone73
in
Advanced Prostate Cancer
6 months ago
Sudden increase of PSA...
My
PSA
numbers after 3 years of Lupron were steady at 0.2...then last month it went to 13....My oncologist has ordered tests but i am worried...Has anyone experienced a similar rise...?
My
PSA
numbers after 3 years of Lupron were steady at 0.2...then last month it went to 13....My oncologist has ordered tests but i am worried...Has anyone experienced a similar rise...?
Max24
in
Advanced Prostate Cancer
8 months ago
Long Journey
Over the years
PSA
would rise, and I would be put on Lupron for 18-24 months. In 2017,
PSA
started rising fast. Brought an MO into the mix. I was placed on Lupron, Xgeva and Erleada (apalutamide). That worked for 5.5 years until we figured out Erleada was making me dizzy.
Over the years
PSA
would rise, and I would be put on Lupron for 18-24 months. In 2017,
PSA
started rising fast. Brought an MO into the mix. I was placed on Lupron, Xgeva and Erleada (apalutamide). That worked for 5.5 years until we figured out Erleada was making me dizzy.
MJCA
in
Prostate Cancer And Gay Men
6 months ago
Xtandi worked great
After radiation to prostate bed and to one pelvic metastasis, I was on xtandi and Lupton for three years and now have been on "vacation " for a year with
PSA
of 0.02 and testosterone at 4. No meds at all for last11 months!
After radiation to prostate bed and to one pelvic metastasis, I was on xtandi and Lupton for three years and now have been on "vacation " for a year with
PSA
of 0.02 and testosterone at 4. No meds at all for last11 months!
JAK2243
in
Advanced Prostate Cancer
5 months ago
Can i take vacation when already 5 years PSA < 0.01
Cancer of the prostate and pelvic lymph nodes found with PET 1, MRI, biopsy,
PSA
=100.
Cancer of the prostate and pelvic lymph nodes found with PET 1, MRI, biopsy,
PSA
=100.
Vasili
in
Advanced Prostate Cancer
8 months ago
Are bone and CT scans required quarterly if PSA and testosterone are basically zero and no symptoms?
My doc still wants to do full bone and CT scans every 3 months even though my
PSA
and testosterone are zero or very low. And have been for a year now. Is this normal or a bit overkill? I am worried about the radiation but also my novice perception of wasted resources. Thoughts?
My doc still wants to do full bone and CT scans every 3 months even though my
PSA
and testosterone are zero or very low. And have been for a year now. Is this normal or a bit overkill? I am worried about the radiation but also my novice perception of wasted resources. Thoughts?
Wildfun44
in
Advanced Prostate Cancer
4 months ago
PSA testing - time taken to separate serum
The reason being that over time
PSA
levels will reduce if the sample remains whole ie unspun.
The reason being that over time
PSA
levels will reduce if the sample remains whole ie unspun.
Wishyouwerehere
in
Prostate Cancer Network
7 months ago
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