Does anyone else have PSA increasing but scans are stable- if so when do you think it's time To switch meds if your scans are every three months and stable and your feeling fine - and all other bloodwork is fine? Do you stay the course and go by scans and symptoms? Also I'm 81 and on xtandi and lurpon - also
In past tried Zytiga. I had a positive psma with pet scan last march .
what scans? We can’t answer your question knowledgably unless you specify! MRI, CT, BONE, PSMA-PET CT….
Ct scans
Has psma and ct every three months
3 months? Isn’t that too much radiation exposure?
I dont think I believe it's part of standard of care
Sorr for asking but maybe you can share your PSA developement over the last years and PSMA Pet/CT results? Otherwise advice is impossible.
Hi . I had my prostate taken out 2002 and five years later my PSA came back . Ever since than it is moving u and the doctors said not to worry because the scans didn't show anything . 2020 I had covi-19 and since than my psa started going up fast . The doctor again said don't worry but three months ago i had PET PSMA SCAN done and guess what ? My psa was at 119 and there is a new development in the bed of the prostate . Since than they put me on Zitiga 4 tablets a day for six months and an implant of Reseligo 10,8mg in my stomach under the skin which will be replaced after 84 days with another one . After the six months are up I have to go back to the doctors for evaluation . I have never taken any meds before or radiation or chemo therapy .
Dad is 90 and the med onc told us that until he sees radiographic changes, he stays on the same meds. I would ask the medical oncologist.
Oh that's awesome! What does he take and what is his psa- what scans does he get
He takes lupron , xtandi, and xgeva, his psa is 1.1 and he was diagnosed with stage 4 bone mets skull, sternum, ribs, spine, pelvis, humerus, clavicles, lymphnodes psa 1260, in 2016. He just started xtandi last year, he gets a whole body bone scan and a cat scan of the abdomen and pelvis every 6 months.
Which Mets are now visible on the above scans at PSA 1.1? I believe (hopefully) not many visible Mets on bone scan and CT scan at PSA of 1.1.
Alot are still visible but inactive, sclerotic they said, all have been stable since 2016 after he started treatment. He is due for his 6 month scans and psa Jan 29 so fingers crossed.
Why did they introduced Enzalutamide (Xtandi)? What was the PSA? Etc.
I introduced recently Bicalutamide and I could change it to Enzalutamide (Xtandi) if it is not effective enough. My PSA doubling time was very short (less than 2.month). The PSA was 1.8 when Bicalutamide was introduced. Maybe I was waiting too long (because of the scans).
My only visible cancer was in my prostate. You can't see micromets, not even on the PSMA pet CT scan.
After Lupron alone failed at 2 plus years, He was started on Bicalutamide for 18 months then psa started to rise, his started out over 1200 . It was heading up to 75 then it went to around 160 about 3 months later so he said lets pull you off of bicalutamide and see if we get a withdrawal response, he did, it started dropping again after coming off of it so he was off for about a year, then his psa started to rise again, they did a bone scan and said it was suspicious that he had one pelvic met enhancing, so they did one whole pelvic dose of radiation and his psa started to drop again and stabilize for another year. After that year it starting going up so he waited until it got to upper 70's, bone scan showed no active mets and he said lets not wait until this one enhances again or you get any new ones and put you on Xtandi, he gave him the choice of Zytiga with pred or xtandi and dad wasnt keen on taking prednisone so he chose xtandi. I have to say that he's been very fatigued with the xtandi but his psa is lower than it has ever been. We will see what his Feb scans and Jan 29th psa shows this round.
hi Chris.
I’m going through a similar situation myself right now. I’m in a Protac trial and getting bone/cat scans every 3 months. My psa has crept up the last 2 mo from 3’s to 5’s but my scans state no progression or new Mets. As it’s been explained to me and my understanding is PSA tells us that something’s going on that’s not supposed to be (I.e. cancer) but the scans tell us exactly how much and where. I have found in the 4 years I’ve been beating this that it’s very easy to get caught up in psa fluctuations, I’ve now learned that the most important metric is how I feel (pain free) and No progressive. I don’t even blink an eye unless my psa doubles consistently for 3 months in a row. Typically speaking that’s also when you’ll see a change in the scans. I hope this gives you some peace of mind. We live in awesome times!!!
Yes my dads did double over 4 months but the dr said swine things chest abdomen and pelvic ct and pet scans and how he feels.
What is your current PSA?
Scans
PSA rising but scans clear
updated scans post chemo
PSA stable? Good? Bad? 
