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Zytiga ,xtandi or erleada
Kaiser MO plan says will add Zytiga ,xtandi or erleada Been on lupron 2 months, MO now adding zytiga. 2nd opinion from UCSF concurs. Any opinions why they choose Zytiga I have seen a recent study saying Xtandi or Erleada might be better. Doctor Familiarity, Side effects, keep something back in the
Kaiser MO plan says will add Zytiga ,xtandi or erleada Been on lupron 2 months, MO now adding zytiga. 2nd opinion from UCSF concurs. Any opinions why they choose Zytiga I have seen a recent study saying Xtandi or Erleada might be better. Doctor Familiarity, Side effects, keep something back in the
pj1121
in
Advanced Prostate Cancer
11 months ago
Invitro study shows Delta Tocotrienol overcomes Docetaxel resistence in PCa
Necroptosis Induced by Delta-Tocotrienol Overcomes Docetaxel Chemoresistance in Prostate Cancer CellsMarina Montagnani Marelli, Giangiacomo Beretta, Roberta Manuela Moretti International Journal of Molecular Sciences 24 (5), 4923, 2023 Prostate cancer (PCa) represents the fifth cause of cancer death
Necroptosis Induced by Delta-Tocotrienol Overcomes Docetaxel Chemoresistance in Prostate Cancer CellsMarina Montagnani Marelli, Giangiacomo Beretta, Roberta Manuela Moretti International Journal of Molecular Sciences 24 (5), 4923, 2023 Prostate cancer (PCa) represents the fifth cause of cancer death
Graham49
in
Fight Prostate Cancer
11 months ago
PSA Test
Hello everybody Where can I find good information about the readings on PSA tests. As I have posted earlier, my husband had the prostate removed, developed a rezidiv after 5 years, was treated with Proton (based on Hydrogen) radiation in Heidelberg January this year. PSA went down from 0,8 to 0,3.
Hello everybody Where can I find good information about the readings on PSA tests. As I have posted earlier, my husband had the prostate removed, developed a rezidiv after 5 years, was treated with Proton (based on Hydrogen) radiation in Heidelberg January this year. PSA went down from 0,8 to 0,3.
Grommi
in
Advanced Prostate Cancer
9 months ago
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Go-forward Treatment Plan
First of all, I've been an avid reader of this forum over the past 2 years, and wanted to express my gratitude towards the amount of knowledge everyone has been sharing on this site. My father (62 y.o., very healthy) was diagnosed with aggressive PCa (Gleason 9, PSA 58) in Sep 2021, and underwent RALP
First of all, I've been an avid reader of this forum over the past 2 years, and wanted to express my gratitude towards the amount of knowledge everyone has been sharing on this site. My father (62 y.o., very healthy) was diagnosed with aggressive PCa (Gleason 9, PSA 58) in Sep 2021, and underwent RALP
sixmongoos
in
Advanced Prostate Cancer
9 months ago
PSA 9 , age 66 , is there an alternative to biopsy ?
My friend’s PSA went from 5 to 9 in 8 months . He asked me if there is an alternative to biopsy . I told him that there may be something new since I last had a biopsy in 2009.
My friend’s PSA went from 5 to 9 in 8 months . He asked me if there is an alternative to biopsy . I told him that there may be something new since I last had a biopsy in 2009.
PBnative
in
Advanced Prostate Cancer
9 months ago
Decapeptyl/Total hysterectomy
Hi I'm just wondering if anyone has had a total hysterectomy after having decapeptyl SR treatment and has this made an improvement.Endometriosis diagnosis 2005 multiple surgeries decapeptyl injections 2.5 years and ongoing. Monthly pain and bleeding returning with a vengeance pain relief zomorph 30mg
Hi I'm just wondering if anyone has had a total hysterectomy after having decapeptyl SR treatment and has this made an improvement.Endometriosis diagnosis 2005 multiple surgeries decapeptyl injections 2.5 years and ongoing. Monthly pain and bleeding returning with a vengeance pain relief zomorph 30mg
Madcathatter
in
Endometriosis UK
1 year ago
WHAT ARE THE CURRENT EFFECTIVE SALVAGE TREATMENTS IN CASE OF A REOCCURRENCE IF YOU HAVE HAD SBRT,IMRT, WITH PLACEMENT OF GOLD BARS?
It appears that if you had SBRT or like myself IMRT and you were given
gold markers
you cannot do any of the following
salvage treatments in case of a reoccurrence
: Proton therapy, Hifu, Tulsa Pro , Etc. Is this true???? Again a significant fact left out before treatment...
In addition
It appears that if you had SBRT or like myself IMRT and you were given
gold markers
you cannot do any of the following
salvage treatments in case of a reoccurrence
: Proton therapy, Hifu, Tulsa Pro , Etc. Is this true???? Again a significant fact left out before treatment...
In addition
JWS13
in
Advanced Prostate Cancer
7 months ago
I like it, but not too much: Phase 2 trial of a DNA vaccine (pTVG-HP) and nivolumab in patients with nmHSPC
"No patients met the primary endpoint of complete PSA response; however, 4/19 (21%) patients had a PSA decline >50%. Median PSA doubling times were 5.9 months pretreatment, 25.6 months on-treatment (p=0.001), and 9.0 months in the subsequent year off-treatment. The overall median radiographic progression-free
"No patients met the primary endpoint of complete PSA response; however, 4/19 (21%) patients had a PSA decline >50%. Median PSA doubling times were 5.9 months pretreatment, 25.6 months on-treatment (p=0.001), and 9.0 months in the subsequent year off-treatment. The overall median radiographic progression-free
Maxone73
in
Advanced Prostate Cancer
7 months ago
ED & zero libido
Three years on from diagnosis and nearly three year of no sexual function. A big loss between my wife and I thought we don’t really talk about it. My GP prescribes viagra but without the desire, little effect. Also given a pump but something makes me resistant to try it. Having said all this I have
Three years on from diagnosis and nearly three year of no sexual function. A big loss between my wife and I thought we don’t really talk about it. My GP prescribes viagra but without the desire, little effect. Also given a pump but something makes me resistant to try it. Having said all this I have
FortyWinks
in
Advanced Prostate Cancer
9 months ago
I wonder if anyone knows why or has experienced a rise on PSA level (from 70 to 274), 6 months after radiation therapy (VMAT x 26 sessions)?
Before and after radiation therapy, dad was taking Bicalutamide 50 mg and Alfuzosin50 mg together with a quarterly Leuprorelin injection. This month (October), after receiving his Leuprorelin injection, Urologist advised to stop taking Bicalutamide as it is no longer effective due to hormone resistance
Before and after radiation therapy, dad was taking Bicalutamide 50 mg and Alfuzosin50 mg together with a quarterly Leuprorelin injection. This month (October), after receiving his Leuprorelin injection, Urologist advised to stop taking Bicalutamide as it is no longer effective due to hormone resistance
Iloveyoudad
in
Advanced Prostate Cancer
9 months ago
Rising PSA
I had a prostatectomy almost 3 years ago. My PSA has been undetectable (<0.01) for all that time. This week it was .02 I’m going to redo the test to make sure. Then my urologist wants to refer me to a radiation oncologist. Has anyone had any experience with this. It’s really been hard trying to sort
I had a prostatectomy almost 3 years ago. My PSA has been undetectable (<0.01) for all that time. This week it was .02 I’m going to redo the test to make sure. Then my urologist wants to refer me to a radiation oncologist. Has anyone had any experience with this. It’s really been hard trying to sort
MJPH
in
Prostate Cancer And Gay Men
7 months ago
Just joined the club no one wants to be a member of in April 2023 - can Gleason 9 be cured ?
Doc says that our goal is a cure despite the fact that I am a Gleason 9 with Decipher score of 1 , the highest for metatastic spread. (PSMA PET was negative.) The highest my PSA has ever been was 5.48 in December 2022 and it dropped to .09 with Testosterone of 14 in August two months after a shot of
Doc says that our goal is a cure despite the fact that I am a Gleason 9 with Decipher score of 1 , the highest for metatastic spread. (PSMA PET was negative.) The highest my PSA has ever been was 5.48 in December 2022 and it dropped to .09 with Testosterone of 14 in August two months after a shot of
68Guitar
in
Advanced Prostate Cancer
10 months ago
Should I be concernedPSA rising from 0.3 to 0.40
after being undetectable for ~ 5 years my PSA became detectable 0.10 in July. In October I was retested and my PSA was 0.30 . In early November I had a PSMA-Pet scan which was negative. Today I was retested with a result of 0.40. How soon should I followup with my MO? Any advice would be appreciated
after being undetectable for ~ 5 years my PSA became detectable 0.10 in July. In October I was retested and my PSA was 0.30 . In early November I had a PSMA-Pet scan which was negative. Today I was retested with a result of 0.40. How soon should I followup with my MO? Any advice would be appreciated
Rfs1975
in
Advanced Prostate Cancer
7 months ago
Peeing , what to do?
My husband has had issues with peeing for years ( probably why stage 4 at diagnosis, cause blamed BPH) . He recently finished last chemo 3 weeks ago and is again noticing a change when peeing. Says that he feels a great deal of pressure towards the end of the pee stream and feels like the end of his
My husband has had issues with peeing for years ( probably why stage 4 at diagnosis, cause blamed BPH) . He recently finished last chemo 3 weeks ago and is again noticing a change when peeing. Says that he feels a great deal of pressure towards the end of the pee stream and feels like the end of his
positive-thinking
in
Advanced Prostate Cancer
3 months ago
PSMA Scan post Ra223 treatments
No huge win from his recent treatment is discernable. The doctor (RO) says there's no way of knowing if it won him any extra time. However, we can only assume things might have been worse without it. As we walked out the door, he came back to us specifically to tell us how good he looked (unstated..
No huge win from his recent treatment is discernable. The doctor (RO) says there's no way of knowing if it won him any extra time. However, we can only assume things might have been worse without it. As we walked out the door, he came back to us specifically to tell us how good he looked (unstated..
Tinuriel
in
Advanced Prostate Cancer
11 months ago
Psa doubled in less than a month
I had 10 infusions of Doxytaxel. I started reading about the consequences of CDK12 and was concerned that since I have this mutation doxy was not a treatment of choice. After giving time for the PSA to settle I had a test which showed that it doubled in close to 3 months. In preparation for a CT and
I had 10 infusions of Doxytaxel. I started reading about the consequences of CDK12 and was concerned that since I have this mutation doxy was not a treatment of choice. After giving time for the PSA to settle I had a test which showed that it doubled in close to 3 months. In preparation for a CT and
spencoid2
in
Advanced Prostate Cancer
10 months ago
timing between Lupron injections
After 17 months on firmagon injections, I switched to the 84 day lupron injection on June 15. How far can the 84 days be safely extended? I am currently scheduled for another injection on September 14, which is 91 days. I hope that is ok, as our scheduling was extended because of vacation conflicts
After 17 months on firmagon injections, I switched to the 84 day lupron injection on June 15. How far can the 84 days be safely extended? I am currently scheduled for another injection on September 14, which is 91 days. I hope that is ok, as our scheduling was extended because of vacation conflicts
Gatodd
in
Advanced Prostate Cancer
11 months ago
Do I need 6th Pluvicto infusion? PSA undetectable for 6 months.
I've been on the PSMAddition trial having had 5 of 6th infusions. PSA undetectable (<0.02) since June (it was 0.31 in early May when accepted into trial with relatively low burden PSMA-avid lesions). Aug 4 CT/bone scans showed significant reductions in size and activity of lesions (prior to 3rd treatment
I've been on the PSMAddition trial having had 5 of 6th infusions. PSA undetectable (<0.02) since June (it was 0.31 in early May when accepted into trial with relatively low burden PSMA-avid lesions). Aug 4 CT/bone scans showed significant reductions in size and activity of lesions (prior to 3rd treatment
LongTimeRunning
in
Advanced Prostate Cancer
7 months ago
Enzalutamide (Xtandi): Start at half standard dose to extend efficacy time span?
Good Morning AllI was disgnosed 6 years ago with oligometastic prostate cancer Gleeson 8, PSA 22. Since January 2018 I have been on ADT, had docetaxel chemo in April 2018, radiotherapy to the prostate, seminal vessel and pelvis in November 2018 when PSA dropped to <0.1. PSMA PET CT scan in March 2019
Good Morning AllI was disgnosed 6 years ago with oligometastic prostate cancer Gleeson 8, PSA 22. Since January 2018 I have been on ADT, had docetaxel chemo in April 2018, radiotherapy to the prostate, seminal vessel and pelvis in November 2018 when PSA dropped to <0.1. PSMA PET CT scan in March 2019
KGU1
in
Advanced Prostate Cancer
10 months ago
Just had My Monthly Injection of Firmagon Monthly Labs PSA is Up <0.06 to 0.09
That’s pretty modest. I’m assuming I will wait till next month to see if it goes down. Kind of stressed with this new diverticulitis and blood bowel thing AND Moving. Got results of psa after I saw My Medical Oncologist so haven’t discussed modest jump. Even with bleeding from rectum the gastroenterologist
That’s pretty modest. I’m assuming I will wait till next month to see if it goes down. Kind of stressed with this new diverticulitis and blood bowel thing AND Moving. Got results of psa after I saw My Medical Oncologist so haven’t discussed modest jump. Even with bleeding from rectum the gastroenterologist
Shorehousejam
in
Advanced Prostate Cancer
10 months ago
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