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WHAT ARE THE CURRENT EFFECTIVE SALVAGE TREATMENTS IN CASE OF A REOCCURRENCE IF YOU HAVE HAD SBRT,IMRT, WITH PLACEMENT OF GOLD BARS?
It appears that if you had SBRT or like myself IMRT and you were given
gold markers
you cannot do any of the following
salvage treatments in case of a reoccurrence
: Proton therapy, Hifu, Tulsa Pro , Etc. Is this true???? Again a significant fact left out before treatment...
In addition
It appears that if you had SBRT or like myself IMRT and you were given
gold markers
you cannot do any of the following
salvage treatments in case of a reoccurrence
: Proton therapy, Hifu, Tulsa Pro , Etc. Is this true???? Again a significant fact left out before treatment...
In addition
JWS13
in
Advanced Prostate Cancer
5 months ago
I like it, but not too much: Phase 2 trial of a DNA vaccine (pTVG-HP) and nivolumab in patients with nmHSPC
"No patients met the primary endpoint of complete PSA response; however, 4/19 (21%) patients had a PSA decline >50%. Median PSA doubling times were 5.9 months pretreatment, 25.6 months on-treatment (p=0.001), and 9.0 months in the subsequent year off-treatment. The overall median radiographic progression-free
"No patients met the primary endpoint of complete PSA response; however, 4/19 (21%) patients had a PSA decline >50%. Median PSA doubling times were 5.9 months pretreatment, 25.6 months on-treatment (p=0.001), and 9.0 months in the subsequent year off-treatment. The overall median radiographic progression-free
Maxone73
in
Advanced Prostate Cancer
5 months ago
Prostate cancer - repurposed drugs?
I am 60 and have been diagnosed with localised, non-metastatic, low grade prostate cancer: Grade 1/Gleason 6 cT2c intermediate risk 65 cc size (moderate) A detailed CT-PET scan (PSMA) (in addition to biopsy and MRI) lit up a fair bit and has shown moderate amount of bilateral disease but oddly in
I am 60 and have been diagnosed with localised, non-metastatic, low grade prostate cancer: Grade 1/Gleason 6 cT2c intermediate risk 65 cc size (moderate) A detailed CT-PET scan (PSMA) (in addition to biopsy and MRI) lit up a fair bit and has shown moderate amount of bilateral disease but oddly in
Thunderball1
in
Fight Prostate Cancer
10 months ago
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Rising PSA
I had a prostatectomy almost 3 years ago. My PSA has been undetectable (<0.01) for all that time. This week it was .02 I’m going to redo the test to make sure. Then my urologist wants to refer me to a radiation oncologist. Has anyone had any experience with this. It’s really been hard trying to sort
I had a prostatectomy almost 3 years ago. My PSA has been undetectable (<0.01) for all that time. This week it was .02 I’m going to redo the test to make sure. Then my urologist wants to refer me to a radiation oncologist. Has anyone had any experience with this. It’s really been hard trying to sort
MJPH
in
Prostate Cancer And Gay Men
5 months ago
My 72 yr old Brother MRI Result Question what to do next?
Should he continue active surveillance? He is going for a biopsy and most likely radiation Have his prostate removed or radiation? Any helpful advice appreciated EXAMINATION: MRI prostate without contrast IMPRESSION: Lesion #1: Apex left posterior peripheral zone, 1.7 cm, slightly increased
Should he continue active surveillance? He is going for a biopsy and most likely radiation Have his prostate removed or radiation? Any helpful advice appreciated EXAMINATION: MRI prostate without contrast IMPRESSION: Lesion #1: Apex left posterior peripheral zone, 1.7 cm, slightly increased
Shorehousejam
in
Advanced Prostate Cancer
10 months ago
Should I be concernedPSA rising from 0.3 to 0.40
after being undetectable for ~ 5 years my PSA became detectable 0.10 in July. In October I was retested and my PSA was 0.30 . In early November I had a PSMA-Pet scan which was negative. Today I was retested with a result of 0.40. How soon should I followup with my MO? Any advice would be appreciated
after being undetectable for ~ 5 years my PSA became detectable 0.10 in July. In October I was retested and my PSA was 0.30 . In early November I had a PSMA-Pet scan which was negative. Today I was retested with a result of 0.40. How soon should I followup with my MO? Any advice would be appreciated
Rfs1975
in
Advanced Prostate Cancer
5 months ago
Now what?
My husband was DX April 2021 MPc, Stage IV, PSA 335, BRACA2. Lupron, Erleada, Provenge, Lynparza (still on), Zytiga/Pred (still on). PSA rose from 2.64 Feb 2023 to 44 Sept 2023. Biggest jumps on the last three months, 10 to 44. He is approved for 177lu, but there are a lot of unsuccessful stories
My husband was DX April 2021 MPc, Stage IV, PSA 335, BRACA2. Lupron, Erleada, Provenge, Lynparza (still on), Zytiga/Pred (still on). PSA rose from 2.64 Feb 2023 to 44 Sept 2023. Biggest jumps on the last three months, 10 to 44. He is approved for 177lu, but there are a lot of unsuccessful stories
Hidden
in
Advanced Prostate Cancer
8 months ago
PSA still low but cancer progressing
I've been on ADT plus Xtandi for about a year (see my profile) and my PSA has steadily reduced and stayed low. However, my latest CT scan shows that the tumours on my bones and lymph nodes are increasing in size and there are now a few small lesions appearing in my liver for the first time. Not the news
I've been on ADT plus Xtandi for about a year (see my profile) and my PSA has steadily reduced and stayed low. However, my latest CT scan shows that the tumours on my bones and lymph nodes are increasing in size and there are now a few small lesions appearing in my liver for the first time. Not the news
Benkaymel
in
Advanced Prostate Cancer
8 months ago
Am I candidate for AS?
66 year old, Dx January 2022 PSA peak 5.76 [u]Biopsy 3/15/22[/u] 3 of 14 cores PCa 1 of 4 cores, 4+3, 80% Gr 4, <5% of tissue, left posterior 2 of 2 cores, 3+4, 20% Gr 4, 20% of tissue, left mid Decipher .34, cut off for low aggression is .45 NanoKnife June 6, 2022 PSA nadir 1.21 [u]Biopsy 5/16
66 year old, Dx January 2022 PSA peak 5.76 [u]Biopsy 3/15/22[/u] 3 of 14 cores PCa 1 of 4 cores, 4+3, 80% Gr 4, <5% of tissue, left posterior 2 of 2 cores, 3+4, 20% Gr 4, 20% of tissue, left mid Decipher .34, cut off for low aggression is .45 NanoKnife June 6, 2022 PSA nadir 1.21 [u]Biopsy 5/16
Piano777
in
Prostate Cancer Network
8 months ago
Do I need 6th Pluvicto infusion? PSA undetectable for 6 months.
I've been on the PSMAddition trial having had 5 of 6th infusions. PSA undetectable (<0.02) since June (it was 0.31 in early May when accepted into trial with relatively low burden PSMA-avid lesions). Aug 4 CT/bone scans showed significant reductions in size and activity of lesions (prior to 3rd treatment
I've been on the PSMAddition trial having had 5 of 6th infusions. PSA undetectable (<0.02) since June (it was 0.31 in early May when accepted into trial with relatively low burden PSMA-avid lesions). Aug 4 CT/bone scans showed significant reductions in size and activity of lesions (prior to 3rd treatment
LongTimeRunning
in
Advanced Prostate Cancer
5 months ago
PSA 6.9 six years after prostatectomy but PET/CT negative?
Weird situation here. Had a prostatectomy at Hopkins in early 2018. Organ-confined but Gleason on pathology was 4+5. For a little over two years PSA remained undetectable...and then, well, I kind of slacked off the test. Stupid and reckless on my part. After a roughly 3-year interval I recently
Weird situation here. Had a prostatectomy at Hopkins in early 2018. Organ-confined but Gleason on pathology was 4+5. For a little over two years PSA remained undetectable...and then, well, I kind of slacked off the test. Stupid and reckless on my part. After a roughly 3-year interval I recently
Nittany
in
Advanced Prostate Cancer
9 months ago
Has anybody used Immucura clinics ?
Hi All, Has anybody used this clinic.. https://sender3.zohoinsights.eu/ck1/13ef.4aba358de/52998e20-9a8f-11ee-ae28-5254002420aa/79e0e7dcd769f1a82f624b9a91845fe7611ef03f/1?e=veESl5RWLMzB2z2VdaUL3CUq0DH9HEX%2FaTvkyymfYCc%3D I'm looking for next stepping stone.. Had nanoknife in 2018, and although psa
Hi All, Has anybody used this clinic.. https://sender3.zohoinsights.eu/ck1/13ef.4aba358de/52998e20-9a8f-11ee-ae28-5254002420aa/79e0e7dcd769f1a82f624b9a91845fe7611ef03f/1?e=veESl5RWLMzB2z2VdaUL3CUq0DH9HEX%2FaTvkyymfYCc%3D I'm looking for next stepping stone.. Had nanoknife in 2018, and although psa
321adam
in
Advanced Prostate Cancer
5 months ago
Whole pelvic radiation after testicular cancer?
My husband is 63, dx Oct/2022 with PSA of ~11 and all twelve cores positive with GL 8 and mostly 9’s (4+5). He had SVI, PNI, and probable ECE, but PSMA PET showed no spread. He’s being treated at UCHealth/Denver CO at their urologic cancer center. His treatment consisted of 39 radiation sessions +
My husband is 63, dx Oct/2022 with PSA of ~11 and all twelve cores positive with GL 8 and mostly 9’s (4+5). He had SVI, PNI, and probable ECE, but PSMA PET showed no spread. He’s being treated at UCHealth/Denver CO at their urologic cancer center. His treatment consisted of 39 radiation sessions +
Adendino
in
Advanced Prostate Cancer
8 months ago
Effect of Constipation on PSA
Found this. https://pubmed.ncbi.nlm.nih.gov/22040453/
Found this. https://pubmed.ncbi.nlm.nih.gov/22040453/
dhccpa
in
Advanced Prostate Cancer
5 months ago
Prostate cancer - no metastases - treat now with repurposed drugs?
Prostate cancer - no metastases - treat now with repurposed drugs? I am 60 and have been diagnosed with localised, non-metastatic, low grade prostate cancer: Grade 1/Gleason 6, T2c, intermediate risk. A detailed CT-PET scan (PSMA) (in addition to biopsy and MRI) has shown moderate amount of bilateral
Prostate cancer - no metastases - treat now with repurposed drugs? I am 60 and have been diagnosed with localised, non-metastatic, low grade prostate cancer: Grade 1/Gleason 6, T2c, intermediate risk. A detailed CT-PET scan (PSMA) (in addition to biopsy and MRI) has shown moderate amount of bilateral
Thunderball1
in
Advanced Prostate Cancer
10 months ago
My scans showed spread but......
My scans showed no spread but Sept 1 my right nipple became very sensitive and a 2" diameter hardness formed around it. I applied Clio twice a day and today the hardened area is the size of a dime. The Clio I use is 5-chloro-7-iodoquinolin-8-ol). U of Maryland is the best source of cancer research that
My scans showed no spread but Sept 1 my right nipple became very sensitive and a 2" diameter hardness formed around it. I applied Clio twice a day and today the hardened area is the size of a dime. The Clio I use is 5-chloro-7-iodoquinolin-8-ol). U of Maryland is the best source of cancer research that
agnut
in
Advanced Prostate Cancer
8 months ago
I just started Zytiga and at the age of 86 I'm finding it difficult to climb stairs; I do have a slow heartbeat when at rest: mid to high 40
I just started Zytiga and at the age of 86 I'm finding it difficult to climb stairs; I do have a slow heartbeat when at rest: mid to high 40s. I've been on Orgovyx for 3 months, when I added Xytiga, which was added because Orgovyx was only able to bring my PSA from 12 to 1.8. Thoughts, Terry
I just started Zytiga and at the age of 86 I'm finding it difficult to climb stairs; I do have a slow heartbeat when at rest: mid to high 40s. I've been on Orgovyx for 3 months, when I added Xytiga, which was added because Orgovyx was only able to bring my PSA from 12 to 1.8. Thoughts, Terry
Poollover
in
Advanced Prostate Cancer
5 months ago
Gleason 6, 1 Yr AS, now Gleason 3+4
Hi, I'm 65, fit, active. , 2 yrs ago noticed PSA doubled to 2.4, last yr 3.5 so had MRI and urine exosome test, "liquid biopsy". Range is 1-100, less than 15 and you are ok, o/w suggest a biopsy. Mine was 48. Oh, the 3 markers in this test are for more aggressive disease. BTW MRI only showed diffuse
Hi, I'm 65, fit, active. , 2 yrs ago noticed PSA doubled to 2.4, last yr 3.5 so had MRI and urine exosome test, "liquid biopsy". Range is 1-100, less than 15 and you are ok, o/w suggest a biopsy. Mine was 48. Oh, the 3 markers in this test are for more aggressive disease. BTW MRI only showed diffuse
Muggs1
in
Prostate Cancer Network
8 months ago
clioquinol + zinc
PSA 44 started clioquinol +zinc Aug 11. Aug 30 PSA 48 with severe UTI. U of Maryland says Clio + zinc kills cancer cells. They give two cases of prostate cancer terminated. I'm trying it.
PSA 44 started clioquinol +zinc Aug 11. Aug 30 PSA 48 with severe UTI. U of Maryland says Clio + zinc kills cancer cells. They give two cases of prostate cancer terminated. I'm trying it.
agnut
in
Advanced Prostate Cancer
8 months ago
PSA up to 150 on Olaprib, any insight on what’s next?
Hi all, my dads history is mostly in my profile but in short he started on Zytiga a year ago. Zytiga worked well but had major side effects and lead to a switch to Erleada. Erleada failed at the time shown in the picture with the orange circle and he switched to Olaprib by the time he got the PSA results
Hi all, my dads history is mostly in my profile but in short he started on Zytiga a year ago. Zytiga worked well but had major side effects and lead to a switch to Erleada. Erleada failed at the time shown in the picture with the orange circle and he switched to Olaprib by the time he got the PSA results
StayingSTRNG
in
Advanced Prostate Cancer
8 months ago
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