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What does ‘neuroendocrine differentiation' mean in metastatic prostate cancer?
My 71 year old dad has been diagnosed with metastatic prostate cancer with neuroendocrine differentiation - he had absolutely zero symptoms until a lymph node on his neck swelled up. It’s metastasised to his lower spine and sternum too. He’s just had his oncology appointment today and they’re going to
My 71 year old dad has been diagnosed with metastatic prostate cancer with neuroendocrine differentiation - he had absolutely zero symptoms until a lymph node on his neck swelled up. It’s metastasised to his lower spine and sternum too. He’s just had his oncology appointment today and they’re going to
NikkiJayne
in
Advanced Prostate Cancer
2 months ago
Abiraterone weaning
When the time comes to stop ADT and abiraterone, for good reasons. Does anyone here have info on abiraterone weaning planning? Including prednisone weaning? TIA
When the time comes to stop ADT and abiraterone, for good reasons. Does anyone here have info on abiraterone weaning planning? Including prednisone weaning? TIA
Derf4223
in
Advanced Prostate Cancer
2 months ago
adding to 10 Concerns
Still evaluating my 10 concerns (POST is here: https://healthunlocked.com/prostate-cancer-community/posts/150936522/recent-diagnosis-questions-concerns-please-respond-to-any-that-you-can) with second opinion evaluation at the end of the month. I wanted to add this personal data below. I am giving myself
Still evaluating my 10 concerns (POST is here: https://healthunlocked.com/prostate-cancer-community/posts/150936522/recent-diagnosis-questions-concerns-please-respond-to-any-that-you-can) with second opinion evaluation at the end of the month. I wanted to add this personal data below. I am giving myself
G6AS
in
Prostate Cancer Network
2 months ago
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Bad reaction after stopping abiraterone?
Have any of you gentlemen had a bad reaction when stopping abiraterone? I’ve been in the current study for LU-PSMA-617 for the past 14 months; it’s evaluating the effectiveness of Pluvicto given at the beginning of the journey before chemo, but i’ve been in the control group. My last bone scan July 12
Have any of you gentlemen had a bad reaction when stopping abiraterone? I’ve been in the current study for LU-PSMA-617 for the past 14 months; it’s evaluating the effectiveness of Pluvicto given at the beginning of the journey before chemo, but i’ve been in the control group. My last bone scan July 12
NewGame
in
Advanced Prostate Cancer
2 months ago
Doing well after surgery and diagnosis of lung cancer
Hi, I am in the process of waiting to see if my lung nodule has grown which is a spickulated one and I have lost weight. My ct scan results will be a couple of weeks after when I thought so this is quite stressful. On the Internet there is lot of negative stories about lung cancer and I was advised
Hi, I am in the process of waiting to see if my lung nodule has grown which is a spickulated one and I have lost weight. My ct scan results will be a couple of weeks after when I thought so this is quite stressful. On the Internet there is lot of negative stories about lung cancer and I was advised
YellowBirdLady
in
The Roy Castle Lung Cancer Foundation
2 months ago
Syncromune Granted FDA Fast-Track Designation for SYNC-T SV-102 for the Treatment of Metastatic Castrate-Resistant Prostate Cancer (mCRPC)
FORT LAUDERDALE, Fla., July 01, 2024 (GLOBE NEWSWIRE) -- Syncromune® Inc., a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for solid tumor cancers, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for SYNC-T SV
FORT LAUDERDALE, Fla., July 01, 2024 (GLOBE NEWSWIRE) -- Syncromune® Inc., a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for solid tumor cancers, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for SYNC-T SV
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
What would cause spontaneous prostate stimulation?
What would cause spontaneous prostate stimulation while lying on my back? When I lie down, in a few seconds it feels like someone is manually stimulating my prostate. This lasts for hours at a time and I cannot sleep. This started immediately after a nocturnal emission, and I haven't had one since, even
What would cause spontaneous prostate stimulation while lying on my back? When I lie down, in a few seconds it feels like someone is manually stimulating my prostate. This lasts for hours at a time and I cannot sleep. This started immediately after a nocturnal emission, and I haven't had one since, even
Hidden
in
Men's Health Forum
2 months ago
Estradiol Patch
Hi Everyone My husband (diagnosed November 2013 see bio ) November 2023 prescribed 2nd generation Xtandi as Zoladex injections became castrate resistent, he has no mets. The full dose became intolerable so Onc lowered it to 2 x 80mg, things were going ok psa was dropping good, then started to slow
Hi Everyone My husband (diagnosed November 2013 see bio ) November 2023 prescribed 2nd generation Xtandi as Zoladex injections became castrate resistent, he has no mets. The full dose became intolerable so Onc lowered it to 2 x 80mg, things were going ok psa was dropping good, then started to slow
Knittingque
in
Advanced Prostate Cancer
2 months ago
Antiandrogen Withdrawal Syndrome After Stopping Enzalutamide in Metastatic Castration-Resistant Prostate Cancer: Two Case Reports & Review
https://www.cureus.com/articles/267994-antiandrogen-withdrawal-syndrome-after-discontinuation-of-enzalutamide-in-patients-with-metastatic-castration-resistant-prostate-cancer-a-report-of-two-clinical-cases-and-a-literature-review#!/ Abstract Metastatic prostate cancer treatment is based on
https://www.cureus.com/articles/267994-antiandrogen-withdrawal-syndrome-after-discontinuation-of-enzalutamide-in-patients-with-metastatic-castration-resistant-prostate-cancer-a-report-of-two-clinical-cases-and-a-literature-review#!/ Abstract Metastatic prostate cancer treatment is based on
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
depression and prostate cancer
I hope everyone is having a nice weekend! My dad’s story is in my bio. My dad becomes very depressed and tearful the week following his Firmagon injections. His doctor has offered antidepressants, but he refuses. He said they will make him more fatigued, although he has never been on them. Has
I hope everyone is having a nice weekend! My dad’s story is in my bio. My dad becomes very depressed and tearful the week following his Firmagon injections. His doctor has offered antidepressants, but he refuses. He said they will make him more fatigued, although he has never been on them. Has
Concerneddaughter123
in
Advanced Prostate Cancer
2 months ago
Old Guy Update
I was diagnosed in November 2020 with stage 4 Ductal adenocarcinoma of the prostate. I had EBRT and 24 months of ADT which was terminated in October of 2022. My PSA at that time was undetectable and my Testosterone was also undetectable. It’s now July 2024, and my PSA is 0.2 and my Testosterone is 10
I was diagnosed in November 2020 with stage 4 Ductal adenocarcinoma of the prostate. I had EBRT and 24 months of ADT which was terminated in October of 2022. My PSA at that time was undetectable and my Testosterone was also undetectable. It’s now July 2024, and my PSA is 0.2 and my Testosterone is 10
TottenhamMan
in
Advanced Prostate Cancer
2 months ago
Unexpected rise in PSA
Hi guys (and girls) My Husbands psa has been climbing steadily over the past year, got up to 47in Jan , hes six years in with MPC from the start . psa 310, five mets.Had Doxytaxel straight away, now on Abi/Pred/or the last 3 years, plus lupron from the beginning. I have been pushing our OC for spot
Hi guys (and girls) My Husbands psa has been climbing steadily over the past year, got up to 47in Jan , hes six years in with MPC from the start . psa 310, five mets.Had Doxytaxel straight away, now on Abi/Pred/or the last 3 years, plus lupron from the beginning. I have been pushing our OC for spot
16starsky
in
Advanced Prostate Cancer
2 months ago
PSA at 0.285
I had my RP last January but the cancers had sneaked out to my lymph node already (no other met) so my PSA was always detectable. I started hormonal therapy last April and my PSA went down right away. It had been that way till this week ( PSA was up and down, the lowest was 0.02, usually was 0.05.).
I had my RP last January but the cancers had sneaked out to my lymph node already (no other met) so my PSA was always detectable. I started hormonal therapy last April and my PSA went down right away. It had been that way till this week ( PSA was up and down, the lowest was 0.02, usually was 0.05.).
Formosan
in
Advanced Prostate Cancer
2 months ago
Looking for Hope
My dad had his second Pluvicto treatment yesterday. His PSA is still rising. The doctor at University of Chicago is not happy with his bloodwork. He may try something else. Before Pluvicto he had Docetaxel and his PSA rose right after he stopped chemo. He also had target radiation that did nothing either
My dad had his second Pluvicto treatment yesterday. His PSA is still rising. The doctor at University of Chicago is not happy with his bloodwork. He may try something else. Before Pluvicto he had Docetaxel and his PSA rose right after he stopped chemo. He also had target radiation that did nothing either
Jshaw916
in
Advanced Prostate Cancer
2 months ago
Triple therapy?
My husband was diagnosed in Feb. 2018 with oligo metastatic - 2 spots on spine and local lymph node involvement. Had radiation to the lymph nodes and was on Lupron and Casodex for 5 years. Went off treatment a year and three months ago. Cancer returned to one lung only - no Mets to bone or lymph
My husband was diagnosed in Feb. 2018 with oligo metastatic - 2 spots on spine and local lymph node involvement. Had radiation to the lymph nodes and was on Lupron and Casodex for 5 years. Went off treatment a year and three months ago. Cancer returned to one lung only - no Mets to bone or lymph
Ljrwife
in
Advanced Prostate Cancer
2 months ago
Liver cancer
finally got to talk to a very knowledgeable liver specialist having been trying to get some answers for months. He understood why I wanted to know and given some idea how long I can expect too live. He went into a lot of detail fully explaining all the scenarios, which is exactly what my wife and I wanted
finally got to talk to a very knowledgeable liver specialist having been trying to get some answers for months. He understood why I wanted to know and given some idea how long I can expect too live. He went into a lot of detail fully explaining all the scenarios, which is exactly what my wife and I wanted
oap74
in
British Liver Trust
2 months ago
Hormone Therapy
.Hi..So my husband was diagnosed with Prostate Cancer via a routine check during a GPs appointment...It was 2020,and we went into lockdown for Covid not long after..He elected to have a Prostatectomy, but unfortunately his PSA never went to zero...Levels remained low, and he had a PET scan, which
.Hi..So my husband was diagnosed with Prostate Cancer via a routine check during a GPs appointment...It was 2020,and we went into lockdown for Covid not long after..He elected to have a Prostatectomy, but unfortunately his PSA never went to zero...Levels remained low, and he had a PET scan, which
debbiejayn
in
Advanced Prostate Cancer
2 months ago
The continuing saga of Scout and Coco, Not all change is welcome.
It is with sadness that I report that My "vacation" may come to an abrupt end . After cruising along with an Undetectable PSA for a little over 2+ years, my recent test results indicate a PSA of 0.03 and my Testosterone jumped from <7 to 13. The good news is my T is coming back but it looks like
It is with sadness that I report that My "vacation" may come to an abrupt end . After cruising along with an Undetectable PSA for a little over 2+ years, my recent test results indicate a PSA of 0.03 and my Testosterone jumped from <7 to 13. The good news is my T is coming back but it looks like
Scout4answers
in
Advanced Prostate Cancer
2 months ago
Xtandi did not work.
Hi all, I'm new to this board but would love some feedback. My father, 80, has been dealing with prostate cancer for a few years. He had initially had radiation plus Lupron injections. His PSA started rising again a few years ago and he wound up on Lupron regularly. His PSA has been slowly rising
Hi all, I'm new to this board but would love some feedback. My father, 80, has been dealing with prostate cancer for a few years. He had initially had radiation plus Lupron injections. His PSA started rising again a few years ago and he wound up on Lupron regularly. His PSA has been slowly rising
Estivez71
in
Advanced Prostate Cancer
2 months ago
Dad’s blood reports. PSA and testosterone down but ALP up
Did some blood tests for day today The last blood tests were done on 2nd May - PSA 18 Alk Phos 180 which led to the prostate cancer diagnosis. Was diagnosed with bone mets to a few bones. Initially the plan was to do lupron and he was started on bicalutamide which he took for 3 weeks uptil 7th
Did some blood tests for day today The last blood tests were done on 2nd May - PSA 18 Alk Phos 180 which led to the prostate cancer diagnosis. Was diagnosed with bone mets to a few bones. Initially the plan was to do lupron and he was started on bicalutamide which he took for 3 weeks uptil 7th
Tinkudi
in
Advanced Prostate Cancer
2 months ago
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