Search
Search
About
Log in
Join
Experiences with
Parkinsonism
Posts
Communities
1,721 public posts
Filter results
Getting stuff across the BBB & exactly where you want it in the brain - through the nose, with ultrasound (in mice)
Getting stuff (name your favorite bioactive molecule) into the brain, especially exactly where you want it to go, can be very difficult. Here's an innovative approach to the problem using intranasal drug delivery combined with ultrasound. The study was on mice of course, but all technological development
Getting stuff (name your favorite bioactive molecule) into the brain, especially exactly where you want it to go, can be very difficult. Here's an innovative approach to the problem using intranasal drug delivery combined with ultrasound. The study was on mice of course, but all technological development
Rhyothemis
in
Cure Parkinson's
5 years ago
Two different Parkinsons
Parkinson is an extremely complex disease but broadly speaking it is categorised into tremor dominant and rigidity dominant. But the 2 have very fundamental and philosophical differences. As someone with tremor dominant PD, I know stress and anxiety is a core backbone of the disease. From comments
Parkinson is an extremely complex disease but broadly speaking it is categorised into tremor dominant and rigidity dominant. But the 2 have very fundamental and philosophical differences. As someone with tremor dominant PD, I know stress and anxiety is a core backbone of the disease. From comments
Grumpy77
in
Cure Parkinson's
5 years ago
Piperlongumine, an active constituent of the Indian spices pippali and ganthoda, increases autophagy in cell and mouse models of PD
Piper longumen's dried flower spike is an Indian spice called pippali and the dried root is called ganthoda. The taste of pippali is peppery and the fragrance is of rose and citrus and perhaps a bit musky. I have no idea how much one would have to eat to induce types of activities reported in this article
Piper longumen's dried flower spike is an Indian spice called pippali and the dried root is called ganthoda. The taste of pippali is peppery and the fragrance is of rose and citrus and perhaps a bit musky. I have no idea how much one would have to eat to induce types of activities reported in this article
Rhyothemis
in
Cure Parkinson's
5 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
Alpha Ketoglutarate?
Just came across the following piece of information and was wondering if anybody here tried Alpha ketoglutarate? "Alpha-ketoglutarate dehydrogenase is also a major participant in mitochondrial function and neurodegenerative disease. There are reduced levels of alphaketoglutarate dehydrogenase in the
Just came across the following piece of information and was wondering if anybody here tried Alpha ketoglutarate? "Alpha-ketoglutarate dehydrogenase is also a major participant in mitochondrial function and neurodegenerative disease. There are reduced levels of alphaketoglutarate dehydrogenase in the
faridaro
in
Cure Parkinson's
5 years ago
GingeMan
I started with PMR seven months ago just before I was due to have a knee replacement. I was on 15mg pred and my consultant refused to operate due to an increased risk of infection until my pred intake was 5mg or less. I am now on 5mg and doing OK and I have arranged an appointment with the consultant
I started with PMR seven months ago just before I was due to have a knee replacement. I was on 15mg pred and my consultant refused to operate due to an increased risk of infection until my pred intake was 5mg or less. I am now on 5mg and doing OK and I have arranged an appointment with the consultant
parsifalwiz
in
PMRGCAuk
5 years ago
A rare cause of axial worsening in Parkinson’s disease: A case of myasthenic pseudo-parkinsonism
https://filebin.net/8k4dgcpa8thfeuu2/Clinical_Neurology_and_Neurosurgery_Volume_179_issue_2019__doi_10.1016_j.clineuro.2019.02.009__Marano,_Massimo__Lanzone,_Jacopo__di_Biase,_Lazzaro__Pepe,_Aless_--_A_rare_cause_of_axial_worsening_in_.pdf?t=9pgbq3gk
https://filebin.net/8k4dgcpa8thfeuu2/Clinical_Neurology_and_Neurosurgery_Volume_179_issue_2019__doi_10.1016_j.clineuro.2019.02.009__Marano,_Massimo__Lanzone,_Jacopo__di_Biase,_Lazzaro__Pepe,_Aless_--_A_rare_cause_of_axial_worsening_in_.pdf?t=9pgbq3gk
Farooqji
in
Cure Parkinson's
5 years ago
Survival in Parkinson Disease Dependent on Parkinsonian Type, Characteristics
https://www.neurologyadvisor.com/movement-disorders/reduced-survival-in-idiopathic-
parkinsonism
/article/825786/
https://www.neurologyadvisor.com/movement-disorders/reduced-survival-in-idiopathic-
parkinsonism
/article/825786/
Farooqji
in
Cure Parkinson's
6 years ago
Melatonin and its importance in Parkinsons
This is an excellent link to learn the importance of certain natural substances that can help Parkinsons patients. https://www.intechopen.com/books/a-synopsis-of-parkinson-s-disease/melatonin-in-parkinson-s-disease Note in particular the actions of Acytil Carnitine, Curcumin, Resveratrol, and Melatonin
This is an excellent link to learn the importance of certain natural substances that can help Parkinsons patients. https://www.intechopen.com/books/a-synopsis-of-parkinson-s-disease/melatonin-in-parkinson-s-disease Note in particular the actions of Acytil Carnitine, Curcumin, Resveratrol, and Melatonin
slippy
in
Cure Parkinson's
5 years ago
Parkinsonism
Symptoms for me started in 2013 and I was diagnosed in 2014 with the
parkinsonism
. I hope this helps.”
Symptoms for me started in 2013 and I was diagnosed in 2014 with the
parkinsonism
. I hope this helps.”
Hidden
in
Cure Parkinson's
6 years ago
experts review current research
https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd181481 "Experts review current research trends and evaluate which of these are likely to succeed over the next two decades, in a special supplement to the Journal of Parkinson’s Disease " Understanding of the processes involved in
https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd181481 "Experts review current research trends and evaluate which of these are likely to succeed over the next two decades, in a special supplement to the Journal of Parkinson’s Disease " Understanding of the processes involved in
melodie
in
Cure Parkinson's
5 years ago
Transcranial Magnetic Stimulation (TMS)
Has anyone here tried TMS and if so for what type of symptomatology? What were your results? I tried searching the archives and only came across a few scattered posts and nothing from anyone who has actually tried it for PD. My main goal for my mom is to reduced her resting tremor and improve her mood
Has anyone here tried TMS and if so for what type of symptomatology? What were your results? I tried searching the archives and only came across a few scattered posts and nothing from anyone who has actually tried it for PD. My main goal for my mom is to reduced her resting tremor and improve her mood
gilgamesh
in
Cure Parkinson's
5 years ago
Parkinsonism
https://youtu.be/NAfQoviLFR8
https://youtu.be/NAfQoviLFR8
Hidden
in
Cure Parkinson's
6 years ago
PD: Search for the Holy Grail
🔼 Hint: The ever elusive "Holy Grail" lies among these little blue arrows 🔼 "We believe we can be optimistic that the next 20 years will see major breakthroughs towards the discovery of therapies that may slow, stop, or reverse PD." It's hard to be overly optimistic after 2 centuries without a solution
🔼 Hint: The ever elusive "Holy Grail" lies among these little blue arrows 🔼 "We believe we can be optimistic that the next 20 years will see major breakthroughs towards the discovery of therapies that may slow, stop, or reverse PD." It's hard to be overly optimistic after 2 centuries without a solution
PDConscience
in
Cure Parkinson's
5 years ago
The perfect Ham Sandwich 😁
How do you define gourmet? It sorta rolls off the tongue: Gourmet. GooooooRR-Mayyyyyyy. Sounds delicious. And for the perfect ham sandwich, gourmet mustard is a must. It adds that spice and flavor that makes its it so mouthwatering As ham sandwiches go, it was perfection. A thick slab of smoked ham,
How do you define gourmet? It sorta rolls off the tongue: Gourmet. GooooooRR-Mayyyyyyy. Sounds delicious. And for the perfect ham sandwich, gourmet mustard is a must. It adds that spice and flavor that makes its it so mouthwatering As ham sandwiches go, it was perfection. A thick slab of smoked ham,
MELNEL
in
Lung Conditions Community Forum
5 years ago
Dihydroergocryptine
Dihydroergocryptine (DHEC, trade names Almirid, Cripar) is a dopamine agonist of the ergoline chemical class that is used as an antiparkinson agent.[1] Dihydroergocryptine has been shown to be particularly effective as monotherapy in the early stages of Parkinson's disease. Initial monotherapy with a
Dihydroergocryptine (DHEC, trade names Almirid, Cripar) is a dopamine agonist of the ergoline chemical class that is used as an antiparkinson agent.[1] Dihydroergocryptine has been shown to be particularly effective as monotherapy in the early stages of Parkinson's disease. Initial monotherapy with a
Farooqji
in
Cure Parkinson's
5 years ago
Anyone had a recent look at Methionine?
It was discussed here 3 years ago and looked promising. People cited articles from the 1980s. https://healthunlocked.com/parkinsonsmovement/posts/133952177/researchers-discover-why-l-dopa-stops-working A quick google scholar search throws up stuff like: Methionine sulfoxide reductase A protects dopaminergic
It was discussed here 3 years ago and looked promising. People cited articles from the 1980s. https://healthunlocked.com/parkinsonsmovement/posts/133952177/researchers-discover-why-l-dopa-stops-working A quick google scholar search throws up stuff like: Methionine sulfoxide reductase A protects dopaminergic
ElliotGreen
in
Cure Parkinson's
5 years ago
Miracle Cures in Parkinson's Disease
An article published in 1975. I use one of the remedies mentioned in this article. That's belladonna extract. Helps in controlling excessive sweating and rigidity https://www.bmj.com/content/3/5974/1
An article published in 1975. I use one of the remedies mentioned in this article. That's belladonna extract. Helps in controlling excessive sweating and rigidity https://www.bmj.com/content/3/5974/1
Farooqji
in
Cure Parkinson's
5 years ago
Could this be "freezing"?
I'm new to this forum, I have not been diagnosed yet. I had been misdiagnosed with Polimyalgia Rheumatica and treated with steroids and a biological drug for two years when I realized that my symptoms were getting worse and were not responding to the drugs. I am now awaiting a muscle biopsy to rule out
I'm new to this forum, I have not been diagnosed yet. I had been misdiagnosed with Polimyalgia Rheumatica and treated with steroids and a biological drug for two years when I realized that my symptoms were getting worse and were not responding to the drugs. I am now awaiting a muscle biopsy to rule out
Gaijin
in
Cure Parkinson's
5 years ago
reversal of Parkinson’s symptoms?
Alan Hoffman says nilotinib has changed his life. Just weeks after he started taking the drug in a clinical trial, he began to feel himself recovering from his Parkinson’s disease. https://www.newscientist.com/article/dn28371-drug-reversed-my-parkinsons-symptoms-and-let-me-read-again/
Alan Hoffman says nilotinib has changed his life. Just weeks after he started taking the drug in a clinical trial, he began to feel himself recovering from his Parkinson’s disease. https://www.newscientist.com/article/dn28371-drug-reversed-my-parkinsons-symptoms-and-let-me-read-again/
Farooqji
in
Cure Parkinson's
5 years ago
Please share your experiences of Parkinson's
Hi, I am from Pakistan. Parkinson's is in my family from the last 2 generations. I am here for my father who was diagnosed before 20 years. He took Kamadrine 5mg in first ten years & after that he added Sinemet 25 mg on daily basis. Please share your experiences of Parkinson's; Your year of diagnosis
Hi, I am from Pakistan. Parkinson's is in my family from the last 2 generations. I am here for my father who was diagnosed before 20 years. He took Kamadrine 5mg in first ten years & after that he added Sinemet 25 mg on daily basis. Please share your experiences of Parkinson's; Your year of diagnosis
naveedahsan
in
Cure Parkinson's
5 years ago
1
...
48
49
50
...
87
Next page
10
20
30
40
50
60
70
80
Filter results
Clear filters
Posted in
All communities
Cure Parkinson's
1371 results
PSP Association
123 results
Thyroid UK
72 results
View top 10 communities
Sort by
Most Relevant
Newest