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Olaparib
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3rd recurrence
But now her avastin and
olaparib
options are done. What next now ?? And one more thing I wanted to mention that she has responded to chemo quite well everytime. Do we have any immunotherapy left now ? I'm little panicking right now. Need your advice.
But now her avastin and
olaparib
options are done. What next now ?? And one more thing I wanted to mention that she has responded to chemo quite well everytime. Do we have any immunotherapy left now ? I'm little panicking right now. Need your advice.
HealthyBeing
in
My Ovacome
8 months ago
Update
I am going to have 1 more round of carbo, just so that I am eligible to have
Olaparib
plus I will have three weekly infusions of Avastin. I am totally gutted with the outcome and am struggling to regain the positivity I felt going into surgery. It was not what I was expecting. x
I am going to have 1 more round of carbo, just so that I am eligible to have
Olaparib
plus I will have three weekly infusions of Avastin. I am totally gutted with the outcome and am struggling to regain the positivity I felt going into surgery. It was not what I was expecting. x
Beaver54
in
My Ovacome
6 months ago
clinical trials and dropped off a cliff
Five years ago I joined the Astra Zeneca clinical trial of
Olaparib
with Zytiga, through my oncologist at Fox Chase in Philadelphia. Earlier this year A-Z ended the trial and applied for FDA approval of the combo, it does seem to help some of us.
Five years ago I joined the Astra Zeneca clinical trial of
Olaparib
with Zytiga, through my oncologist at Fox Chase in Philadelphia. Earlier this year A-Z ended the trial and applied for FDA approval of the combo, it does seem to help some of us.
Johnkelsey
in
Advanced Prostate Cancer
6 months ago
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1 year since my operation so celebrated on holiday's šš š¬š·
I'm also on
olaparib
, it's been a battle with joint pains and fatigue but I'm still here!!. I was stage 4 hgsc brca negative but hrd positive at diagnosis and am now NED š„³š„° holding ca 125 at 7.
I'm also on
olaparib
, it's been a battle with joint pains and fatigue but I'm still here!!. I was stage 4 hgsc brca negative but hrd positive at diagnosis and am now NED š„³š„° holding ca 125 at 7.
Newbery3
in
My Ovacome
8 months ago
NICE review of first-line olaparib - your comments needed
Hello All NICE are undertaking a Cancer Drugs Fund guidance review for
olaparib
.
Hello All NICE are undertaking a Cancer Drugs Fund guidance review for
olaparib
.
OvacomeSupport
My Ovacome Team
in
My Ovacome
10 months ago
is there any hope for me
Diagnosed Dec 2019 stage 3c now stage 4 metastasis Here is how much I have fought: Dec2019 full debunking surgery Chemo: carbo/taxol/avastin Jan 2020 avastin continued until April 2021 when reoccurrence Carbo/doxil from May to Nov. 2021
Olaparib
until March 2022 Cisplatin and Gemzar April to
Diagnosed Dec 2019 stage 3c now stage 4 metastasis Here is how much I have fought: Dec2019 full debunking surgery Chemo: carbo/taxol/avastin Jan 2020 avastin continued until April 2021 when reoccurrence Carbo/doxil from May to Nov. 2021
Olaparib
until March 2022 Cisplatin and Gemzar April to
Summergold2
in
My Ovacome
6 months ago
What else is available?
A year on Avastin and
Olaparib
with progression. Then my onc tried Carboplatin and then Caelyx neither of which worked and the size of my tumour is what it was at the start of treatment. Iāve never had surgery.
A year on Avastin and
Olaparib
with progression. Then my onc tried Carboplatin and then Caelyx neither of which worked and the size of my tumour is what it was at the start of treatment. Iāve never had surgery.
Guilane
in
My Ovacome
9 months ago
Update on cabazitaxel
There is the option of adding
Olaparib
, or waiting until the end of the chemo treatments, projected to be as many as 10, and then moving to
Olaparib
.
There is the option of adding
Olaparib
, or waiting until the end of the chemo treatments, projected to be as many as 10, and then moving to
Olaparib
.
Arcticfox44
in
Advanced Prostate Cancer
9 months ago
Rechallenging with a previously failed treatment?
For example, I was on
Olaparib
(being BRCA2+) successfully for 18 months before it failed. Now there are treatments/trials combining
Olaparib
with another med like Abiraterone, which I had also previously failed as a mono therapy. Could a combo now possibly benefit me???
For example, I was on
Olaparib
(being BRCA2+) successfully for 18 months before it failed. Now there are treatments/trials combining
Olaparib
with another med like Abiraterone, which I had also previously failed as a mono therapy. Could a combo now possibly benefit me???
HopingForTheBest1
in
Advanced Prostate Cancer
10 months ago
Pembrolizimumab after Olaparib - ICI after PARPi + BAT
There are very good results, it seems that prolonged use of
Olaparib
upregulates PD-L1 to a high extent. Has anybody tried Pembro after
Olaparib
? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585736/
There are very good results, it seems that prolonged use of
Olaparib
upregulates PD-L1 to a high extent. Has anybody tried Pembro after
Olaparib
? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7585736/
Hidden
in
Fight Prostate Cancer
1 year ago
Olaparib - how long to get used to it
Hi allI've been taking
Olaparib
for just under a month now. I don't have terrible side-effects but am often tired and nauseous. (I'm on my second anti-nausea medication and can try others and may be considering lowering the
Olaparib
dose.)
Hi allI've been taking
Olaparib
for just under a month now. I don't have terrible side-effects but am often tired and nauseous. (I'm on my second anti-nausea medication and can try others and may be considering lowering the
Olaparib
dose.)
Demelzatheseagull
in
My Ovacome
11 months ago
Clinical Trial with Abemaciclib and Olaparib
Hey Queens! I am reaching out to see if anyone is participating in this clinical trial. I am having a hard time deciding if this is a āfavorableā option for me. Iād love to get some type of feedback from an actual patient. Itās fairly new, so any findings seem impossible to come by. Also, Iā
Hey Queens! I am reaching out to see if anyone is participating in this clinical trial. I am having a hard time deciding if this is a āfavorableā option for me. Iād love to get some type of feedback from an actual patient. Itās fairly new, so any findings seem impossible to come by. Also, Iā
TealBlooms
in
My Ovacome
10 months ago
Latest Treatments for Advanced Prostate Cancer
Olaparib
has been shown to improve survival and delay cancer progression in men with advanced prostate cancer who have mutations in genes involved in DNA repair, such as BRCA1 or BRCA234.
Olaparib
was approved by the FDA in 2020 for this group of men.
Olaparib
has been shown to improve survival and delay cancer progression in men with advanced prostate cancer who have mutations in genes involved in DNA repair, such as BRCA1 or BRCA234.
Olaparib
was approved by the FDA in 2020 for this group of men.
NecessarilySo
in
Advanced Prostate Cancer
10 months ago
lymparza/olaparix/olanib
My doctor told me to start
Olaparib
, in Panama si very expensive have anyone usted a geneneric instead of lymparza? I found two: olaparix and olanib. thanks For Any advice āŗļøš¤
My doctor told me to start
Olaparib
, in Panama si very expensive have anyone usted a geneneric instead of lymparza? I found two: olaparix and olanib. thanks For Any advice āŗļøš¤
Marylight
in
My Ovacome
11 months ago
Dental care on Olaparib?
I am on
Olaparib
. Is it ok to have my tooth filled or taken out? Anyone know? Thanks, Emma
I am on
Olaparib
. Is it ok to have my tooth filled or taken out? Anyone know? Thanks, Emma
Trickysite
in
My Ovacome
11 months ago
FDA approves olaparib/abiraterone for BRCA-positive mCRPC
https://www.urologytimes.com/view/fda-approves-
olaparib
-abiraterone-for-brca-positive-mcrpc?utm_source=sfmc&utm_medium=email&utm_campaign=05312023_UT_BREAKINGNEWS&eKey=b3NoZWFwNjQ2QGdtYWlsLmNvbQ==
https://www.urologytimes.com/view/fda-approves-
olaparib
-abiraterone-for-brca-positive-mcrpc?utm_source=sfmc&utm_medium=email&utm_campaign=05312023_UT_BREAKINGNEWS&eKey=b3NoZWFwNjQ2QGdtYWlsLmNvbQ==
pca2004
in
Fight Prostate Cancer
1 year ago
hair care with olaparib
has anyone tried hair colouring or smoothening when on
olaparib
. My grays have become prominent in the last year and my hairs are growing back curly (never had curls before in my life) after the chemo.
has anyone tried hair colouring or smoothening when on
olaparib
. My grays have become prominent in the last year and my hairs are growing back curly (never had curls before in my life) after the chemo.
Goodgirl98
in
My Ovacome
11 months ago
NHS agrees to roll out Olaparib (Lynparza) April 2023.
The drug,
olaparib
(LynparzaĀ®), targets cancers with mutations in the BRCA genes, and works by stopping cancer cells from being able to repair their DNA by blocking a molecule called PARP, which causes the cancerous cells to die.
The drug,
olaparib
(LynparzaĀ®), targets cancers with mutations in the BRCA genes, and works by stopping cancer cells from being able to repair their DNA by blocking a molecule called PARP, which causes the cancerous cells to die.
Sailing-Todd
in
Advanced Prostate Cancer
1 year ago
Clinical trials
Followed by 18 months of
Olaparib
which then stopped working late last year.
Followed by 18 months of
Olaparib
which then stopped working late last year.
testarossa71
in
My Ovacome
7 months ago
Any experience with fever please?
Treatments have been RPT in 15, 1st line ADT, RT to prostatic bed in 19, enzalutamide, 6 cycles Docetaxel ending Jan 23,
Olaparib
until April, currently on Aberaterone. PSA jumped from 2.8 July 22 to 729 March 23. It seems Chemo and
Olaparib
werenāt effective.
Treatments have been RPT in 15, 1st line ADT, RT to prostatic bed in 19, enzalutamide, 6 cycles Docetaxel ending Jan 23,
Olaparib
until April, currently on Aberaterone. PSA jumped from 2.8 July 22 to 729 March 23. It seems Chemo and
Olaparib
werenāt effective.
Cdel
in
Advanced Prostate Cancer
1 year ago
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