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Silly Questions??
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
TommyCarz2
in
Advanced Prostate Cancer
4 months ago
Low cortisol, low T3 results-pls advise, terrified I’ll have to stop work as just exhausted
hi.. I’m on levo 100mg for at least a year now, been diagnosed hypothyroid for 2 years I think. . Had these tests done privately dec 2023. Previous test a year before saw lower TSH - seemed to have climbed up, and higher T3 than before. I haven’t shown to GP yet- partly cos just depressed and exhausted
hi.. I’m on levo 100mg for at least a year now, been diagnosed hypothyroid for 2 years I think. . Had these tests done privately dec 2023. Previous test a year before saw lower TSH - seemed to have climbed up, and higher T3 than before. I haven’t shown to GP yet- partly cos just depressed and exhausted
Midlake
in
Thyroid UK
4 months ago
Allergic reaction to Doxil, my first ever chemo infusion
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
penpen18
in
SHARE Metastatic Breast Cancer
4 months ago
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Ectopics - one after the other. So scared
Hi everyone. I posted on this forum a few years ago and everyone was so helpful. I wonder if anyone could offer some advice/reassurance? Quick back sorry. I had an SVT around 2.5 years ago and ended up in hospital. Had all tests and nothing wrong. Was put on 1.25mg Bisoprolol which made me horribly
Hi everyone. I posted on this forum a few years ago and everyone was so helpful. I wonder if anyone could offer some advice/reassurance? Quick back sorry. I had an SVT around 2.5 years ago and ended up in hospital. Had all tests and nothing wrong. Was put on 1.25mg Bisoprolol which made me horribly
mummyofspot
in
British Heart Foundation
4 months ago
Any suggestions please.
Hello. I wonder if you would be kind enough to give me your views on my latest results please. I currently take 100mcg thyroxine at bedtime. My GP withdrew my T3 ( 5mcg) around 5 years ago. Apparently it doesn't work and was too expensive. I feel dreadful. I'm underweight with a BMI of 18 and on top
Hello. I wonder if you would be kind enough to give me your views on my latest results please. I currently take 100mcg thyroxine at bedtime. My GP withdrew my T3 ( 5mcg) around 5 years ago. Apparently it doesn't work and was too expensive. I feel dreadful. I'm underweight with a BMI of 18 and on top
andreab
in
Thyroid UK
4 months ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
4 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
4 months ago
Advanced prostate cancer
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Catdog1111
in
Advanced Prostate Cancer
4 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
4 months ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
4 months ago
Operation
Hi everybody! So I was diagnosed PMR 2 years ago and started on 25mg of pref. I am now down to 5mg. I saw my Rumy a few weeks ago who did bloods ect and seems to think my PMR is over! However I’m due to have a hip replacement on the 5th December which I’m so happy about as I’ve been in agony for a long
Hi everybody! So I was diagnosed PMR 2 years ago and started on 25mg of pref. I am now down to 5mg. I saw my Rumy a few weeks ago who did bloods ect and seems to think my PMR is over! However I’m due to have a hip replacement on the 5th December which I’m so happy about as I’ve been in agony for a long
Holycow2
in
PMRGCAuk
7 months ago
Hypogonadal - 4 months Orgovyxx- 1 year later- No recovery to baseline 286 only at 98- No libido- TRT?
Gleason 7 4-3..IMRT 20 txs finished 2/28 No after effects went fine except for 4 months adt (orgovyxx) ..still little recovery (T-98) 1 year after ending adt 5/23 recovery only to 98 in one year , baseline before adt 286 with everything working fine. Stopped 5/23 Orgovyxx Still Hypogonadal ( T-98) 1
Gleason 7 4-3..IMRT 20 txs finished 2/28 No after effects went fine except for 4 months adt (orgovyxx) ..still little recovery (T-98) 1 year after ending adt 5/23 recovery only to 98 in one year , baseline before adt 286 with everything working fine. Stopped 5/23 Orgovyxx Still Hypogonadal ( T-98) 1
JWS13
in
Advanced Prostate Cancer
1 month ago
calprotectin levels
Hi just seeing if anyone is in same position or has been Basically I’ve been having bowel issues since I had my son jan 2022 I stayed having constipation lose bowels with blood mucus urgency to go stomach cramps ect So doctor said I needed to do calprotectin test and that came back at 157 repeated
Hi just seeing if anyone is in same position or has been Basically I’ve been having bowel issues since I had my son jan 2022 I stayed having constipation lose bowels with blood mucus urgency to go stomach cramps ect So doctor said I needed to do calprotectin test and that came back at 157 repeated
Lo181
in
Bowel Disease Support
7 months ago
Life Expectancy
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
My father was diagnosed with advanced prostate cancer four years ago. Initially, he underwent radiation for a few spots on his ribs and immediately began ADT/Xtandi treatment for two years. His PSA dropped to 0.001, prompting his medical oncologist to recommend a medication vacation. For two years, he
godhelpus
in
Advanced Prostate Cancer
4 months ago
Effect of Baseline T on T-Recovery Time
Here's a plot of % of Men who recover their baseline testosterone after stopping ADT (Lupron), as a function of ADT duration for two different groups: (A) men who had a
normal
baseline testosterone (red line), and (B) men who had a
low
baseline testosterone (green line). Increasing the
Here's a plot of % of Men who recover their baseline testosterone after stopping ADT (Lupron), as a function of ADT duration for two different groups: (A) men who had a
normal
baseline testosterone (red line), and (B) men who had a
low
baseline testosterone (green line). Increasing the
janebob99
in
Prostate Cancer Network
4 months ago
Testosterone Recovery for 50% of Men
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
janebob99
in
Prostate Cancer Network
4 months ago
Testosterone Recovery After ADT - Updated Plot
Thanks to Tall_Allen for providing lots of extra data for this plot: https://www.prostatecancer.news/2023/04/intermittent-adt.html You can easily extrapolate the curves to find out your recovery time. ADT duration of 3-9 months fall roughly on the same curve, and ADT of 18-24 roughly fall on the same
Thanks to Tall_Allen for providing lots of extra data for this plot: https://www.prostatecancer.news/2023/04/intermittent-adt.html You can easily extrapolate the curves to find out your recovery time. ADT duration of 3-9 months fall roughly on the same curve, and ADT of 18-24 roughly fall on the same
janebob99
in
Prostate Cancer Network
4 months ago
Help! on Pro-stap, tibolone HRT brought back endo pain!? Made me so unwell - anyone relate??
pro-stap monthly injections started November without HRT. Reduced lot of the endo pain (although made my stomach issues/sensitivity to food way worse). Decided to start tibolone HRT 10 weeks into the injections and it caused awful period/endo pain, spotting, flu type symptoms on and off. Only lasted
pro-stap monthly injections started November without HRT. Reduced lot of the endo pain (although made my stomach issues/sensitivity to food way worse). Decided to start tibolone HRT 10 weeks into the injections and it caused awful period/endo pain, spotting, flu type symptoms on and off. Only lasted
Flewks
in
Endometriosis UK
4 months ago
What if mri is clear?
Hi, I'm 26 and have always had bad periods as a teenager. Poor health in general but march of this year I started experiencing the most excruciating pain along with weakness, dizziness, nausea, spotting ect. I've been in and out of the hospital all year long with multiple gp appointments and multiple
Hi, I'm 26 and have always had bad periods as a teenager. Poor health in general but march of this year I started experiencing the most excruciating pain along with weakness, dizziness, nausea, spotting ect. I've been in and out of the hospital all year long with multiple gp appointments and multiple
Lavenderpetal
in
Endometriosis UK
7 months ago
Testosterone recovery after stopping ADT - 3
This plot shows the % of men who recovered their original testosterone level after stopping Lupron ADT, plotted versus the time (months) after stopping ADT, for three different durations of ADT (4, 6-12, or 24 months). The curves show that a short course of ADT allows men to recover their testosterone
This plot shows the % of men who recovered their original testosterone level after stopping Lupron ADT, plotted versus the time (months) after stopping ADT, for three different durations of ADT (4, 6-12, or 24 months). The curves show that a short course of ADT allows men to recover their testosterone
janebob99
in
Prostate Cancer Network
4 months ago
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