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OS versus Testosterone Nadir - 4
This plot shows the Overall Survival Probability after RT and ADT, for Advance Prostate Cancer men, comparing different levels of testosterone nadir (< 10 ng/dL, 10-20, and 20-50, The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 10 ng/dL).
[b
This plot shows the Overall Survival Probability after RT and ADT, for Advance Prostate Cancer men, comparing different levels of testosterone nadir (< 10 ng/dL, 10-20, and 20-50, The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 10 ng/dL).
[b
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA relapse rate vs testosterone nadir - 3
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
This plot shows the PSA relapse rate after RT and ADT, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20 ng/dL),
and the relationship
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA Survival vs Testosterone Nadir - 2
This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20
This plot shows the Biochemical Relapse Free Survival after RT and ADT, after 10 years , for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone nadir ( < 20
janebob99
in
Advanced Prostate Cancer
6 months ago
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PSA Survival vs Testosterone Nadir - 1
This plot shows the Biochemical Relapse Free Survival after RT and ADT, versus time for up to 18 years, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone
This plot shows the Biochemical Relapse Free Survival after RT and ADT, versus time for up to 18 years, for Intermediate and High Risk men, comparing different levels of testosterone nadir ( 50 nd/dL). (ref: 2019) The
best
outcomes
are significantly associated with a
lower testosterone
janebob99
in
Advanced Prostate Cancer
6 months ago
Needing advice/suggestions re tweaking NDT
Hello everyone: Hope you’re all doing as well as can be. So, I’m presently taking 90 Erfa + 25 Synthroid, all at once upon waking. I need to make some changes because I’ve lost half the hair on my head, gained 7 lbs and can’t loose the weight, diet has not changed. Been on NDT for the past 2-3 years
Hello everyone: Hope you’re all doing as well as can be. So, I’m presently taking 90 Erfa + 25 Synthroid, all at once upon waking. I need to make some changes because I’ve lost half the hair on my head, gained 7 lbs and can’t loose the weight, diet has not changed. Been on NDT for the past 2-3 years
Rosebud1955
in
Thyroid UK
6 months ago
radiation or no radiation
I Just updated my profile and am G-9 with PNI, IDC and lymphovascular invasion. Check 2 mutation as well but Decipher at .41. RP Dr V Patel march 2020 (T3b, negative margins and negative lymph nodes) and PSA undetectable until Sept 2023. Started at 0.021 and now Feb 22nd 2024 at 0.052. Seeing Dr
I Just updated my profile and am G-9 with PNI, IDC and lymphovascular invasion. Check 2 mutation as well but Decipher at .41. RP Dr V Patel march 2020 (T3b, negative margins and negative lymph nodes) and PSA undetectable until Sept 2023. Started at 0.021 and now Feb 22nd 2024 at 0.052. Seeing Dr
Peppertree602
in
Advanced Prostate Cancer
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, only 65% of HR/VHR
janebob99
in
Prostate Cancer Network
6 months ago
Early Results from Transdermal Estrogen PATCH trial - 2
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
Here's some charts comparing Lupron ADT to transdermal estrogen (TDE) patch therapy for High Risk and Very High Risk men with prostate cancer. The upper chart shows the percentage of men that have been castrated to a testosterone level < 50 ng/dL after 1 month of treatment. For Lupron, 65% of HR/
janebob99
in
Advanced Prostate Cancer
6 months ago
Early Results from Transdermal Estrogen PATCH trial
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Advanced Prostate Cancer
6 months ago
Early Results of Estrogen PATCH trial - 1
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
Here are some Early Results from the first year of the Transdermal Estrogen PATCH trial. References are available on their website at: http://patch.mrcctu.ucl.ac.uk. The cohort was men with High or Very High Risk prostate cancer. Stage T3 (73%) and Stage T4 (14%), baseline PSA = 35 ng/mL. The upper
janebob99
in
Prostate Cancer Network
6 months ago
Estrogen ADT vs Lupron ADT
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
Here's a chart showing % of men who have a given condition, comparing Estrogen ADT versus Lupron ADT. There's big reduction in hot flashes, and improvements in libido, when taking supplemental Estrogen. Estrogen increases gynecomastia (enlarged breasts), however. Bob
janebob99
in
Prostate Cancer Network
6 months ago
Blood Pressure Medication
Unfortunately I now have to start BP medication and GP can only seem to find capsules. As I have problems with Acacia Powder and Cellulose and these seem to be in all BP medication, GP has not found me ones I can take after seeming to look for the last fortnight. Is there anyone on this forum who
Unfortunately I now have to start BP medication and GP can only seem to find capsules. As I have problems with Acacia Powder and Cellulose and these seem to be in all BP medication, GP has not found me ones I can take after seeming to look for the last fortnight. Is there anyone on this forum who
nightingale-56
in
Thyroid UK
6 months ago
Silly Questions??
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
1) Why do some advanced prostate cancer patients get offered "vacations", from ADT and others don't? 2) Why do some advanced prostate cancer patients have NO Chemo, and go directly to ADT + Abiraterone+Prednisone, while others begin treatment with chemo and radiation? What are the deciding criteria
TommyCarz2
in
Advanced Prostate Cancer
6 months ago
Allergic reaction to Doxil, my first ever chemo infusion
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
Hi everyone, Has anyone experienced an allergic reaction to Doxil? Almost three years ago, I was diagnosed with stage 4 MBC. After being on hormone therapy for over two years, mostly IBrance and Letrozole, and then oral chemo for six months, my most recent petscan showed the cancer is still spreading
penpen18
in
SHARE Metastatic Breast Cancer
6 months ago
Timings of NDT and iron supplements
Hi all, I'm struggling to maintain ferritin levels whilst also trying to adhere to the timings of iron supplements around my NDT and other vitamins. My ferritin is rarely higher than 20s (in the last ten years the highest it has been was 52 just once). I've been on NDT for a year and am gradually
Hi all, I'm struggling to maintain ferritin levels whilst also trying to adhere to the timings of iron supplements around my NDT and other vitamins. My ferritin is rarely higher than 20s (in the last ten years the highest it has been was 52 just once). I've been on NDT for a year and am gradually
Maldeerum
in
Thyroid UK
6 months ago
No Osteoporosis with Estrogen Patch Therapy
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
These plots compare results from the Phase-II randomized trial (PATCH) comparing estrogen patch therapy to Lupron ADT. These plots show that Lupron ADT causes bone loss, while estrogen patch therapy has either no bone loss or increased bone mineral density (BMD) over time. Bob
janebob99
in
Prostate Cancer Network
6 months ago
Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and PSA after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
6 months ago
Advanced prostate cancer
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Hey there,I'm just seeing if I can get any insight on this from anyone living this now.My father is 70 and was recently diagnosed with prostate cancer and there was a spot on his rob as well from it.I don't know what stage it is but he is currently on hormone therapy and gets injections every 3 months
Catdog1111
in
Advanced Prostate Cancer
6 months ago
Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
6 months ago
The paradigm has shifted - castrate resistance.
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
It now appears that I’ve entered the land of castrate resistance and further ADT vacations are no longer in the plan. My T level recovered much more quickly during the last vacation than during previous vacations, and my PSA rose correspondingly. At 4 months my T level was 325 and my PSA was 4. Another
fireandice123
in
Advanced Prostate Cancer
6 months ago
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