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Nicotinamide
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My alternative therapy for SCA1.
term=
nicotinamide
+riboside&cond=mitochondrial+biogenesis&rank=1 http://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30482-X http://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00452-5 https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30742-3 https://scienceofparkinsons.com/?
term=
nicotinamide
+riboside&cond=mitochondrial+biogenesis&rank=1 http://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30482-X http://www.cell.com/cell-metabolism/fulltext/S1550-4131(14)00452-5 https://www.cell.com/cell-reports/fulltext/S2211-1247(18)30742-3 https://scienceofparkinsons.com/?
sunvox
in
Ataxia UK
6 years ago
DNA Repair/ Cockayne Syndrome and Niagen.
I knew that
nicotinamide
riboside was headed for a human clinical trial in Cockayne Syndrome, but I never found any underlying animal model research that explained why researchers were interested in this line of study . . . until today. Just found it.
I knew that
nicotinamide
riboside was headed for a human clinical trial in Cockayne Syndrome, but I never found any underlying animal model research that explained why researchers were interested in this line of study . . . until today. Just found it.
sunvox
in
Ataxia UK
7 years ago
Vitamin B
In the first study I link below, mice with Ataxia Telangiactasia were treated using
Nicotinamide
Riboside(NR) or Niagen, and in the second study mice with Huntington's disease were treated using
Nicotinamide
(NAM) a similar but NOT identical vitamin B.
In the first study I link below, mice with Ataxia Telangiactasia were treated using
Nicotinamide
Riboside(NR) or Niagen, and in the second study mice with Huntington's disease were treated using
Nicotinamide
(NAM) a similar but NOT identical vitamin B.
sunvox
in
Ataxia UK
7 years ago
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Neurotransmitter-nutrient relationship (from Dr. Walsh's book "Nutrient Power: heal you biochemistry, heal your brain")
On p.151 there is a table which lists 5 neurotransmitters (serotonin, dopamine, norepinephrine, NMDA, GABA) and nutrients affecting them - in case some of you might be interested in looking at them, here are the ones affecting dopamine: Increased activity : tyrosine, phenylalanine, vitamins B1, B6,
On p.151 there is a table which lists 5 neurotransmitters (serotonin, dopamine, norepinephrine, NMDA, GABA) and nutrients affecting them - in case some of you might be interested in looking at them, here are the ones affecting dopamine: Increased activity : tyrosine, phenylalanine, vitamins B1, B6,
faridaro
in
Cure Parkinson's
7 years ago
NAD
My business partner, a Georgetown MD with a chemical engineering degree from Yale, and I own a NAD treatment center. Part of my hypothesis on how to restore the heart without synthetic meds or ablations, not to include bioidentical hormones, focuses on mitochondria health. NAD is responsible for intracellular
My business partner, a Georgetown MD with a chemical engineering degree from Yale, and I own a NAD treatment center. Part of my hypothesis on how to restore the heart without synthetic meds or ablations, not to include bioidentical hormones, focuses on mitochondria health. NAD is responsible for intracellular
tombeaux
in
AF Association
7 years ago
high dose vit b1 / thiamine warning
Avoid using in the absence of vitamin B6 and
nicotinamide
, as life-threatening brain damage may occur. http://www.mayoclinic.org/drugs-supplements/thiamine/safety/hrb-20060129
Avoid using in the absence of vitamin B6 and
nicotinamide
, as life-threatening brain damage may occur. http://www.mayoclinic.org/drugs-supplements/thiamine/safety/hrb-20060129
Hidden
in
Cure Parkinson's
7 years ago
Trehalose and nicotinamide riboside as treatments for ataxia
However, the long term safety and efficacy has not yet been proven for either Cabaletta (trehalose) or Niagen (
nicotinamide
riboside) so we CANNOT recommend people with ataxia take these.
However, the long term safety and efficacy has not yet been proven for either Cabaletta (trehalose) or Niagen (
nicotinamide
riboside) so we CANNOT recommend people with ataxia take these.
SueMillman
Ataxia UK
in
Ataxia UK
8 years ago
A response to 2Sunny regarding recent posts on trehalose and nicotinamide riboside
Shortly after these results came out, 3 people with FA chose to take
nicotinamide
in large quantities and ended up in hospital with liver failure. Just because a substance shows promising results and is freely available does not mean that it isn’t dangerous.
Shortly after these results came out, 3 people with FA chose to take
nicotinamide
in large quantities and ended up in hospital with liver failure. Just because a substance shows promising results and is freely available does not mean that it isn’t dangerous.
SueMillman
Ataxia UK
in
Ataxia UK
8 years ago
Partial Possible Treatment for some SCAs.
Next Niagen: Niagen is the commercial name for a vitamin B3 discovered in 2004 called
nicotinamide
riboside. It is similar to niacin but it has some interesting effects that niacin does not.
Next Niagen: Niagen is the commercial name for a vitamin B3 discovered in 2004 called
nicotinamide
riboside. It is similar to niacin but it has some interesting effects that niacin does not.
2Sunny
in
Ataxia UK
8 years ago
Study strengthens therapeutic potential for niacin-based diet in treatment of Parkinson's disease
Niagen (
nicotinamide
riboside or NR) is a powerful NAD+ booster and is perhaps the most high tech supplement out there. Do a search for it on google and you will see a lot of studies.
Niagen (
nicotinamide
riboside or NR) is a powerful NAD+ booster and is perhaps the most high tech supplement out there. Do a search for it on google and you will see a lot of studies.
rhenry45
in
Cure Parkinson's
8 years ago
Parkinsons detox
I just joined this forum after seeing my mom struggle so much with her PD. Over the years have introduced mucana , a few supplements , exercise etc , but a recent fall has really pushed her back where she is tired, sleepy and can barely walk (she was only walking with the helper before also) . Wish
I just joined this forum after seeing my mom struggle so much with her PD. Over the years have introduced mucana , a few supplements , exercise etc , but a recent fall has really pushed her back where she is tired, sleepy and can barely walk (she was only walking with the helper before also) . Wish
mymomhaspd
in
Cure Parkinson's
8 years ago
Poor balance
My main issue is poor balance which does improve with exercise but not to the point to which I want. Mirapex does nothing for it. Do you think adding NADH and or Mucina to my list of supplements would help? Or anything else? Thank you T
My main issue is poor balance which does improve with exercise but not to the point to which I want. Mirapex does nothing for it. Do you think adding NADH and or Mucina to my list of supplements would help? Or anything else? Thank you T
AmmieM
in
Cure Parkinson's
8 years ago
The MTHFR gene + homocysteine
And I will continue to use methyltetrahydrofolic acid (the bioavailable form of B6) at bedtime because it is a precursor of GABA which helps to make me sleep: http://www.livestrong.com/article/481527-vitamin-b6-insomnia/ The final B vitamin I take is niacinamide/
nicotinamide
because it has many functions
And I will continue to use methyltetrahydrofolic acid (the bioavailable form of B6) at bedtime because it is a precursor of GABA which helps to make me sleep: http://www.livestrong.com/article/481527-vitamin-b6-insomnia/ The final B vitamin I take is niacinamide/
nicotinamide
because it has many functions
silvestrov
in
Cure Parkinson's
8 years ago
Melatonin
http://www.intechopen.com/books/a-synopsis-of-parkinson-s-disease/melatonin-in-parkinson-s-disease Acetyl-L-carnitine Aspirin (acetylsalicylic acid) Carnitine Caffeine Creatine Curcumin (–)-Epigallocatechin gallate (EGCG) (R)-Lipoic acid Melatonin MLT) (–)-Nicotine
Nicotinamide
Resveratrol
http://www.intechopen.com/books/a-synopsis-of-parkinson-s-disease/melatonin-in-parkinson-s-disease Acetyl-L-carnitine Aspirin (acetylsalicylic acid) Carnitine Caffeine Creatine Curcumin (–)-Epigallocatechin gallate (EGCG) (R)-Lipoic acid Melatonin MLT) (–)-Nicotine
Nicotinamide
Resveratrol
zawy
in
Cure Parkinson's
9 years ago
I want to cure my 1 year old baby from Type 1 daibetes
Hello, My baby is only 19 months old and diagnosed with type 1 diabetes (not genetic). I am determined to do whatever I need to cure him completely. His body is still growing and whatever damage was done to his pancreas can be still reversed, so I am convinced. Please, share with me any knowledge you
Hello, My baby is only 19 months old and diagnosed with type 1 diabetes (not genetic). I am determined to do whatever I need to cure him completely. His body is still growing and whatever damage was done to his pancreas can be still reversed, so I am convinced. Please, share with me any knowledge you
Margaux76
in
Diabetes India
9 years ago
Iodine Excess as an Environmental Risk Factor for Autoimmune Thyroid Disease
Inhibition of a subunit protein of
nicotinamide
adenine dinucleotide phosphate (NADPH) oxidase p67phox (an enzyme that catalyzes the generation of ROS products) by its inhibitor, diphenyleneiodonium, prior to iodine treatment abolishes both iodine-induced ROS generation and ICAM-1 expression in NOD.H
Inhibition of a subunit protein of
nicotinamide
adenine dinucleotide phosphate (NADPH) oxidase p67phox (an enzyme that catalyzes the generation of ROS products) by its inhibitor, diphenyleneiodonium, prior to iodine treatment abolishes both iodine-induced ROS generation and ICAM-1 expression in NOD.H
helvella
Thyroid UK
in
Thyroid UK
9 years ago
fatigue
I have mentioned this before but need some more help with this issue. My husband is on Zandopa and supplements and per a post suggestion, I added Moringa twice a day. I think it's excellent for overall health, however, it's not giving him any energy as others have enjoyed. He naps often...He has used
I have mentioned this before but need some more help with this issue. My husband is on Zandopa and supplements and per a post suggestion, I added Moringa twice a day. I think it's excellent for overall health, however, it's not giving him any energy as others have enjoyed. He naps often...He has used
Nehd
in
Cure Parkinson's
10 years ago
Fatigue & supplements/vitamins?
Hi all, I've had Fibro for a number of years (although only officially diagnosed earlier this year), since childhood I reckon. For many years the main symptoms were pain-related, but more recently, the biggest problem is the cognitive side of the condition. It's ruining my life at the moment...I'm 23
Hi all, I've had Fibro for a number of years (although only officially diagnosed earlier this year), since childhood I reckon. For many years the main symptoms were pain-related, but more recently, the biggest problem is the cognitive side of the condition. It's ruining my life at the moment...I'm 23
HopefulMind
in
Fibromyalgia Action UK
10 years ago
Nicotinamide
At the advice of the Dr at the ataxia centre I have started taking 2g of
Nicotinamide
a day for energy and I have to say I have really noticed a difference.
At the advice of the Dr at the ataxia centre I have started taking 2g of
Nicotinamide
a day for energy and I have to say I have really noticed a difference.
annasgonesailing
in
Ataxia UK
10 years ago
New clinical trial pyruvate, creatine, niacinamide
If any one is in the trial, pls share your first improvements . http://www.google.fr/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0CDAQFjAA&url=http%3A%2F%2Fclinicaltrials.gov%2Fct2%2Fshow%2FNCT00605930&ei=FXJmU-LmBKTT0QWeo4HgBw&usg=AFQjCNGUDUo04X8Wy_5RavDmrwD_LuGsQQ&bvm=bv.65788261,d.d2k
If any one is in the trial, pls share your first improvements . http://www.google.fr/url?sa=t&rct=j&q=&esrc=s&source=web&cd=1&cad=rja&uact=8&ved=0CDAQFjAA&url=http%3A%2F%2Fclinicaltrials.gov%2Fct2%2Fshow%2FNCT00605930&ei=FXJmU-LmBKTT0QWeo4HgBw&usg=AFQjCNGUDUo04X8Wy_5RavDmrwD_LuGsQQ&bvm=bv.65788261,d.d2k
clairev
in
PSP Association
10 years ago
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