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Interesting study on combination of statins and metformin in high-risk patient outcomes
https://www.academia.edu/99363002/Individual_and_joint_effects_of_metformin_and_statins_on_mortality_among_patients_with_high_risk_prostate_cancer?email_work_card=view-paper Interesting paper - basically showing that statins reduce PCa mortality among high-risk PCa patients, metformin doesn't appear
https://www.academia.edu/99363002/Individual_and_joint_effects_of_metformin_and_statins_on_mortality_among_patients_with_high_risk_prostate_cancer?email_work_card=view-paper Interesting paper - basically showing that statins reduce PCa mortality among high-risk PCa patients, metformin doesn't appear
Don_1213
in
Advanced Prostate Cancer
7 months ago
Non metastasis castrate resistant
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Sailameme
in
Advanced Prostate Cancer
7 months ago
After 25 years they have stopped my B12 - what can I do?
I'm in my early sixties. Generally very good health. On no medication. About twenty five years ago my then brilliant GP did a blood test for B12. A few days later rang me to come to the surgery immediately where he injected B12 himself. Apparently I had dangerously low levels of B12 that indicated I
I'm in my early sixties. Generally very good health. On no medication. About twenty five years ago my then brilliant GP did a blood test for B12. A few days later rang me to come to the surgery immediately where he injected B12 himself. Apparently I had dangerously low levels of B12 that indicated I
DIYenthusiast
in
Pernicious Anaemia Society
1 month ago
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Strophantus D4 heart arrhythmia
I have already asked recently about heart arrhythmia since Pred. And it seems many people have that problem. I have been taking Strophantus D4 tablets for a few weeks and have had no more heart attacks at night. Sometimes I still have little heart palpitations. I hope it lasts 🤞🏻
I have already asked recently about heart arrhythmia since Pred. And it seems many people have that problem. I have been taking Strophantus D4 tablets for a few weeks and have had no more heart attacks at night. Sometimes I still have little heart palpitations. I hope it lasts 🤞🏻
Swizzly
in
PMRGCAuk
3 months ago
seeing neurologist, advice on b12 injections welcomed…
hi all? have been prescribed with PA. My ferritin levels are normal - 177 Vitamin D- 70. I have finished loading does for b12 last week. My last reading was 188 2 weeks ago but imagine it’s greater than 2000 now. My folate was low - 3.5. My Gp has helpfully given me folic acid 5 mg a day
hi all? have been prescribed with PA. My ferritin levels are normal - 177 Vitamin D- 70. I have finished loading does for b12 last week. My last reading was 188 2 weeks ago but imagine it’s greater than 2000 now. My folate was low - 3.5. My Gp has helpfully given me folic acid 5 mg a day
Damacian
in
Pernicious Anaemia Society
4 months ago
Not PCa related but sounds like a very promising approach
When I read "advanced pancreatic cancer" and "overall disease control of 94%" in the same document...I feel like smiling.... https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-gene-therapy-plus-chemotherapy/
When I read "advanced pancreatic cancer" and "overall disease control of 94%" in the same document...I feel like smiling.... https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-gene-therapy-plus-chemotherapy/
Maxone73
in
Advanced Prostate Cancer
6 months ago
Do you think I need an increase in my T4 dose???
Hi all, I have hashimoto and hypo since many years. I take T4 medication ( 100 mg) every morning. The brand name is Euthyrox ( the version which has mannitol and citric acid instead of lactose). This is my thyroid test results after 14 months of no tests at all due to lack of medical insurance. I was
Hi all, I have hashimoto and hypo since many years. I take T4 medication ( 100 mg) every morning. The brand name is Euthyrox ( the version which has mannitol and citric acid instead of lactose). This is my thyroid test results after 14 months of no tests at all due to lack of medical insurance. I was
Gigihadad
in
Thyroid UK
7 months ago
What Causes Autoimmune Diseases?
Interesting read...Autoimmune Disease: Why Is My Immune System Attacking Itself?Reviewed By: Ana-Maria Orbai, M.D., M.H.S. Autoimmune disease affects 23.5 million Americans, and nearly 80 percent of those are women. If you’re one of the millions of women affected by this group of diseases, which includes
Interesting read...Autoimmune Disease: Why Is My Immune System Attacking Itself?Reviewed By: Ana-Maria Orbai, M.D., M.H.S. Autoimmune disease affects 23.5 million Americans, and nearly 80 percent of those are women. If you’re one of the millions of women affected by this group of diseases, which includes
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
Wednesday's 'Word'
[u][i]
autoimmune -
[/i][/u] This word refers to a disease in which the body's immune (protection or resistance) system attacks healthy cells. Other autoimmune diseases include lupus, rheumatoid arthritis, celiac, sjogrens syndrome, multiple sclerosis, polymyalgia rheumatica, Type 1 diabetes
[u][i]
autoimmune -
[/i][/u] This word refers to a disease in which the body's immune (protection or resistance) system attacks healthy cells. Other autoimmune diseases include lupus, rheumatoid arthritis, celiac, sjogrens syndrome, multiple sclerosis, polymyalgia rheumatica, Type 1 diabetes
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
ATA Virtual Patient Forum: International Thyroid Awareness Week - Wednesday, May 29, 2024, 8pm - 9:15pm EDT
In case anyone is interested, registration appears to be open - both in they are accepting registrations AND it is open to the public. It would be interesting to find out about how useful it is. The time makes it somewhat awkward for many in the UK. I think it works out to be 01:00 in the morning
In case anyone is interested, registration appears to be open - both in they are accepting registrations AND it is open to the public. It would be interesting to find out about how useful it is. The time makes it somewhat awkward for many in the UK. I think it works out to be 01:00 in the morning
helvella
Thyroid UK
in
Thyroid UK
4 months ago
Examining Prostate Cancer Survival Outcomes by Patient Age and Treatment Type in Patients with mHSPC
“the research suggests a differential impact between androgen receptor antagonists (like enzalutamide, apalutamide, and darolutamide) and androgen synthesis inhibitors (such as abiraterone), with antagonists showing a more pronounced benefit” https://www.urotoday.com/video-lectures/asco-gu-2024/video
“the research suggests a differential impact between androgen receptor antagonists (like enzalutamide, apalutamide, and darolutamide) and androgen synthesis inhibitors (such as abiraterone), with antagonists showing a more pronounced benefit” https://www.urotoday.com/video-lectures/asco-gu-2024/video
Maxone73
in
Advanced Prostate Cancer
7 months ago
Intrinsic Factor result
bit disappointing it didn’t come back positive., but I know they don’t always accurately reflect the underlying condition.It also means my pernicious anaemia could be due to long term use of PPIs rather than autoimmune gastritis. (By the way stopped PPIs in December last year) .
bit disappointing it didn’t come back positive., but I know they don’t always accurately reflect the underlying condition.It also means my pernicious anaemia could be due to long term use of PPIs rather than autoimmune gastritis. (By the way stopped PPIs in December last year) .
Chickens44
in
Pernicious Anaemia Society
4 months ago
Decompensated liver
good morning everyone.looking for information on what to expect.my brother has been diagnosed with Decompensated liver disease after many years of heavy drinking, he’s now a severe alcoholic, He was admitted into hospital 6 weeks ago with all the symptoms of liver disease, he was kept in for Five weeks
good morning everyone.looking for information on what to expect.my brother has been diagnosed with Decompensated liver disease after many years of heavy drinking, he’s now a severe alcoholic, He was admitted into hospital 6 weeks ago with all the symptoms of liver disease, he was kept in for Five weeks
tomgill
in
British Liver Trust
7 months ago
Newbie and blood tests
Good morning all, I've been borderline underactive thyroid for a year or so. I was never told my levels and they aren't on my GP app. I've been retested recently and have a TSH level of 6. I also have a TSH receptor level of 0.3. I have a few symptoms.. Tiredness Brain fog Cold all the time Thinning
Good morning all, I've been borderline underactive thyroid for a year or so. I was never told my levels and they aren't on my GP app. I've been retested recently and have a TSH level of 6. I also have a TSH receptor level of 0.3. I have a few symptoms.. Tiredness Brain fog Cold all the time Thinning
HubbaBubbaLover
in
Thyroid UK
4 months ago
Just some new Information about AI
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
chefjlu
in
Advanced Prostate Cancer
7 months ago
Thoughts on blood test ? (Quite new to T3 meds)
Any thoughts regarding my latest bloods please? I take 100 mcg T4 and 20mcg T3. My symptoms are nausea and brain fog. (I have an Underactive Thyroid). Free T3 5.1 pmol/L (in range) (3.10-6.80pmol)L THS 0.01 pmol/L (out of range) (range 0.27-4.20mIU/L) Free T4
Any thoughts regarding my latest bloods please? I take 100 mcg T4 and 20mcg T3. My symptoms are nausea and brain fog. (I have an Underactive Thyroid). Free T3 5.1 pmol/L (in range) (3.10-6.80pmol)L THS 0.01 pmol/L (out of range) (range 0.27-4.20mIU/L) Free T4
Heyhop
in
Thyroid UK
4 months ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
janebob99
in
Advanced Prostate Cancer
7 months ago
PSA vs Testosterone at high T levels - Linear Model
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
janebob99
in
Advanced Prostate Cancer
7 months ago
PSMA Scan to be scheduled - thank you Tall Allen
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
Geno2853
in
Advanced Prostate Cancer
7 months ago
I'm new to this community , but not to Health Unlocked
I'm John and for several years have posted in HealthUnlocked about atrial fibrillation and stroke. In 2014 I had pulmonary toxicity (cryptogenic organising pnuemonia) secondary to dronedarone and amiodarone. It took three hospital admissions before it was correctly diagnosed. I had read the American
I'm John and for several years have posted in HealthUnlocked about atrial fibrillation and stroke. In 2014 I had pulmonary toxicity (cryptogenic organising pnuemonia) secondary to dronedarone and amiodarone. It took three hospital admissions before it was correctly diagnosed. I had read the American
john-boy-92
in
Lung Conditions Community Forum
3 months ago
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