Experiences with

Lupron

PSA initially at 137 Lupron every six months Bicalutamide worked for about 8-9 months Moved to Xtandi to avoid steriods due to severe glacoma stopped working at 4 months Radiation to the back. Xtandi just failed, PSA has been doubled over 8 weeks and then over the next 4 weeks.

My previous three years on Lupron weren't as hard to endure as they could have been, judging by what I read on this forum and elsewhere. But I have felt well for the past year plus and don't relish having heavier side effects from the "doublet therapy."

Doctors at the hospital recommended the following: IV Decadron 4mg 4x/day which started on 1/3' Bicalutamide 50mg once a day for 14 days Lupron after 2 weeks No surgeries due to his age. He is high risk for paralysis. He set up an appointment with an Oncologist for 1/15.

He also agreed with the doublet therapy he is on (Lupron/Zytiga with pred), and said he would recommend at least two years of this (to my husband’s dismay).

I started Lupron 3 month shots this past August. Abiraterone (4- 250mg tabs/day) was added at same time. I would be interested if someone can explain what the benefit is of adding Abiraterone to the treatment rather than just going with with Lupron 3 month shots alone? Thanks

One of the fun things I am getting as an SE while on lupron/abiraterone/prednisone is fluid retention. Edema and getting up to pee 3-4 times nightly (losing 3-4 lbs of weight during the night.) What if anything can be done about this?

Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s PSA dropped from 2.47-1.46 and pain has been improving.

Am considering it because two years after ADT. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.

While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested

Current cancer treatment is three month lupron depot. PSA is non-detectable. Scans in July showed old mets healed, and no new ones. His fatigue is the same whether we eat low carb or not so I haven't been able to find a correlation with food.

My metastatic prostate cancer was diagnosed castrate resistant on November 1 with PSA of 0.8, which was doubling in about two months while on Lupron. On November 10 I started Abiraterone + prednisone. By December 1 my PSA dropped to 0.44 in 22 days on Abiraterone.

leg cramps. After my third 3month Lipton shot and after starting oxybutinin er, i am having cramps and pain in back of left leg. Totally able to do treadmill and the elliptical but if I have to go up a flight of stairs, the leg cramps just kill me. Anyone had any similar experiences?

I am on Lupron and Abi two months now with <.1 PSA down from 2.2, MO says I can do abi w food if I want, so is it an okay idea to go with 500 or 250mg per day vs 1000, and if so, how many grams of fat constitute the low fat breakfast to eat with the abi? 🙂

I'm no longer taking xtandi, so it can be "washed out" of my system prior to new treatment, however I'm still getting quarterly lupron shots.

One think I might add is I had two compression fractures back when my Psa was 5664 and I started Lupron. TIA.

At this time I am on Lupron only. My numbers have good on both meds. My question is, what if I just take Lupron only? 🤔

Starting tomorrow Abiraterone (Zytiga) and predniSONE and on continuous LUpron.

My daughter is going to be put on this drug for uterine fibroids and potential endometriosis for a period of 7 months and then we'll have surgery for hysterectomy. She is very concerned about the side effects of this medication and I'm wondering if anyone on here has had experience using this medication

He has added Zytiga to Lupron.

Hello - My Med Onc recommended black cohosh for hot flashes under Lupron and abi. After more than 2 months it is not working well enough for me. Last night I tried 300mg of Gabapentin left over from back problems last year and it seemed to do much better, no episodes all night.