Update Castrate Resistant Metastatic Cancer

[dac500]

My metastatic prostate cancer was diagnosed castrate resistant on November 1 with PSA of 0.8, which was doubling in about two months while on Lupron. On November 10 I started Abiraterone + prednisone. By December 1 my PSA dropped to 0.44 in 22 days on Abiraterone. In the next 35 days it went down to 0.34 today. That is the drop has slowed down somewhat, in the first 22 days a drop by about 50% in the next 35 days a drop by about 25%.

I am having serious pins and needle in a left foot toe, which appears like bee sting. My MO doesn't think it is a side effect from Abiraterone. While some men on this site have reported as side effects from Zytiga (Abiraterone). What should I think.

[Izzygirl1]

May be a crazy answer but— Could it be gout? My husband takes meds every day for that. Very painful toe pain when having a gout attack.

[Oceankayaker]

I have been on Zytiga for 2 years and have not experienced that side effect. My SEs are cough, insomnia, arrhythmias (PVC) fatigue.

[Joeym1040]

I have gout and i do not believe it is gout. Gout never gave me pins & needles just significant pain & swelling in the joint.

I also have peripheral neuropathy. Sound like it could be the start of that.

[j-o-h-n]

To dac500,

Zytiga

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bladder pain

bloating or swelling of the face, arms, hands, lower legs, or feet

bloody or cloudy urine

blurred vision

bone pain or fracture

chest pain or discomfort

decreased urine

difficult, burning, or painful urination

dry mouth

fainting

fast, pounding, or irregular heartbeat or pulse

feeling of warmth

frequent urge to urinate

headache

increased thirst

increased urge to urinate during the night

lightheadedness, dizziness, or fainting

loss of appetite

lower back or side pain

mood changes

muscle pain or cramps

nausea

nervousness

numbness or tingling in the hands, feet, or lips <------

pain or swelling in the arms or legs without any injury

passing urine more often

pounding in the ears

rapid weight gain

redness of the face, neck, arms, and occasionally, upper chest

seizures

slow heartbeat

sudden sweating

swelling

swelling with pits or depressions on the skin

trouble breathing

unusual tiredness or weakness

unusual weight gain or loss

vomiting

waking to urinate at night

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 01/07/2024 4:31 PM EST