Diagnosed about 14 months ago with metastasis to spine and prostate bed. Started Lupron and Zytiga w/ prednisone.
I have seriously struggled staying on Zytiga. The usual side effects are bad enough but three months ago my blood pressure spiked to 222/110 sending me to the ER. I’ve never had high blood pressure before this episode.
My oncologist lowered it by half to 500 ml. I’ve been fine until two weeks ago it spiked again. I have stopped taking Zytiga all together and feel much better. My oncologist tells that any replacements to Zytiga will be more harsh as side effects go.
At this time I am on Lupron only. My numbers have good on both meds. My question is, what if I just take Lupron only? 🤔
Written by
OldGuysRule
To view profiles and participate in discussions please or .
Talk to your PC doc about blood pressure drugs. If you are on 5mg of prednisone, try upping to 10mg. That worked for me. Yoga and other exercises can help with bp. Don’t give up on abi, it’s keeping you alive.
I thought abi/pred simply gave one a 7% greater chance of survival which is already pretty darn good on Lupron alone. Is this not the case? I do already have HBP but had to stop the Abi/pred because of a severe cough. The cough still has not completely disappeared and I cannot find anyone who knows anything about it being a side effect. Am I killing myself by stopping the abi/pred?
Thanks for the response. A cough is listed as a side effect of the abiraterone and my doctor endorsed the halt and did not suggest lowering the dose as an alternative.
I was taking 10mg of prednisone and my BP was high. My doc said to lower the dose to 5mg and that lowered my BP to normal. Exactly the opposite of what you are saying.
I have read interesting studies about c above. My husband did great on abi until about the same time period. He managed to stay on for two years and now specialists from two centers of excellence have agreed to, even suggested a vacation fro it and Lupron..his PSA has been Undectable
We are, too! Another good lab result yesterday. Labs every three months. It is predicted that his cancer will return but he feels so good now and he figures the drugs will work again.
some people are helped with side effects by reducing the dose to 250 mg (1 pill) a day taken with a light, low fat meal (like toast with butter or berries and yoghurt). There’s a good discussion on this site at healthunlocked.com/advanced...
It might be worth a try if you can’t switch to erleada.
I've been on lupron now for over two years. My psa at this time is undetected. Normal side effects nothing I can't deal with. I had robotic surgery in 2008. That's all I can share for now. Keep working out as much as you can tolerate it helps to keep some muscle.
Curcumin and magnesium both lower blood pressure naturally however it takes 4 to 8 weeks to reach full benefit. Consult with your oncologist first. I take 450 mg of magnesium and 2800 mg of curcumin daily. Bb is now 130 over 80 midday and about 115 over 75 in the evening. Curcumin relaxes blood vessels and magnesium acts as a calcium channel blocker.
Hi , my husbands BP is often 160 or even 180 / 90 on abi and lupron. MO doesn't seem worried but we are concerned that it is too high. It is always higher at the Dr office (knowing the lupron shot is next) but prior to cancer, his BP was always normal. He does take curcumin daily and has started drinking beet juice. We could add magnesium. But do you think he should be on meds to lower BP? He is scheduled for hip replacement surgery in a few weeks.
I’ve been on Lupron and Zytiga over a year now. I’ve never had BP issues at all. The Zytiga drives my BP high even crazy spikes like 221/111. We’ve lowered the dosage but still it goes high, just not as high. I just started on BP meds for the first time in my life. It makes me sad to keep adding more medications. That’s where we are.
Agreed , we hate to add more medicines ( with more side effects). He is going to a cardiologist to get cleared for the hip replacement - I dont know if they will insist on BP meds or not.
If the bp keeps high n you can’t tolerate the zytiga like I didn’t, then incorporate ivm as its safe n keeps lupron or better yet orgavix from being castrate resistant by recent studies and keeps psa extremely low… good luck 🍀
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.