Experiences with

Lung cancer

Bicalutamide mono therapy worked great for nearly three years. PSA <0.1, T~300-400. Starting Dec. 2023 PSA began rising. Tried Lupron Depot in July. PSA has continued to rise. Now at 2.7. Ga PSMA PET last week reveals only a “mild to moderate uptake in prostate region near residual brachytherapy seeds

Hi- I have been on Tamoxifen for five years- because I had a history of UTIs when I was much younger and was worried about the effects of tamoxifen on bladder and vagina I used local low dose estrogen -Estring or Vagifem depending on what was available - apparently this very localized dose doesn’t affect

Ok, nowadays I tend to post most preclinical research in Fight Prostate Cancer community, but this is too good: https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01833-1 works on cells and on mice models, basically (in a very small nutshell) switching on/off few genes can kill cancer

They stopped the original trial due to the drug not being effective on a single does per day. "Based on initial pharmacokinetic results, two additional dosing cohorts with twice daily (BID) oral dosing of ONCT-534 had been incorporated in the Phase 1/2 study ONCT-534-101 (NCT05917470). Overall, fifteen

As others have correctly said, BAT isn't for everyone. In my case my PSA went up from the get go and after about 4 treatment cycles I was pulled from the trial. The primary trial goal totally failed, when I left the trial my metastases were thriving and my PSA rising. The secondary trial goal also

Dad was saying since some days he feels a sweetish kind of taste in mouth. I have read some people can have a change of taste as a side effect of enzalutamide. He is on relugolix , enzalutamide and have added 2000 mg metformin since a month. Anyone here experiences similar ?

My PSA has been relatively flat, in the .26 to .36 range for 2 years but has now started rising to .71. My MO gave me several options from radiation therapy: A: switching from my Abiraterone & Prednisone (which I have been on for over 4 years now) to Extandi which I can not afford the $3600 monthly

I am 66 years old and have been on Lupron for 12 years along with Abiraterone for most of that time. PSA began rising 3 yrs ago and following a PSMA we did “wack-a-mole” on my largest tumor. PSA became immeasurable again but began rising about 6 months thereafter. PSA rising again for 2 yrs: .05, .06

I have been on tamoxifen for 7 and a half years now but for some reason for the last 4-5 years I get lots of UTI’s which are unpleasant and painful. My GP and oncologist say it is not related to tamoxifen but I wonder if it is as it blocks the estrogen and decreased estrogen can lead to bladder and

Ok, if we suppose that big investors always know what they are doing...here is the following: https://www.rttnews.com/3427517/janux-soars-on-encouraging-trial-data-for-janx007-and-janx008.aspx interim data for advanced prostate cancer should be publicly available within 3 months...but if you find

Anyone have experience with pluvicto.. My husband just had his first treatment today. He has advanced Prostate cancer. Started in- had radiation for 42 days, 2019 recurred and had hormone therapy, 2022 metastasized and received eligard and xtendi, 2023 xtendi no longer effective and he was changed to

I started hormone therapy abitaterome and eligard in April for metastatic prostate cancer. I feel great. When I started my psa was 125. In June it was 7. But my last test in September it was still psa 7. Didn’t go down. Doctor not happy. Would like to see it at 0. Any thoughts ?

To date, I've been more than a bit underwhelmed by the results of PSMA theranostics. When I first learned of the concept, it seemed, at least in theory, to be a potential PCa "silver bullet", esp. when targeting patients still hormone sensitive and PSA avid. Here is a MedPage Today article that summarizes

Here's another 2 minute iteration of this new way to convey prostate cancer information. I modified the style based on your suggestions. Please share your thoughts on this version, too. FYI: The voice is AI. I wrote the script. Thanks for your help! https://youtu.be/xP2eoGw2Vvc

Had Rp June of 23 and 37 treatments of radiation. Currently on Orgovyx, abi and prednisone about 12 months now. I’m having some pretty severe joint pain and just wondering what others are doing to manage it. I was doing well with exercise and then it just forced me to slow down. I am getting some people

I've become castrate resistant after almost 4 yrs. Will be starting chemo taxotere. Ask question on AI copilot. CR after lupron and zytiga metastatic. Effective for 50% of patients. That sucks

Had ctDNA test which revealed a BRCA 1 mutation. Onc placed me on Lynparza 600 mg daily along with Orgovyx daily. psa when started parp was 7.9 thirty days later 9.4 continued same, thirty days later psa 8.2 continued same, thirty days later psa 10.4. Onc was a psma scan to check results, if five

hi, as I’ve been recently diagnosed with bph I have a lot of worries. The medication tamulosin is helping me - even if making me very irritable. I also have bad mental health and anxiety so sometimes I feel my dr isn’t being straight up front with me. I suppose a lot of people have asked for reassurance

After my problems with bowels that persist but are more under control now with new diet & medicine, we concluded that Caelyx/Carbo doesn’t work for me. The marker keeps on going up and down and after sinking from 277 to 197 it was again back to 270 last week. My doctor said my options are weekly taxol

My plan is to have salvage brachytherapy or cryotherapy. The thing is these treatments will take time to be scheduled, especially brachytherapy as this would be with Dr Zelefsky in New York and I don’t have an interview with him until Nov 19. I meet with my urologist on Oct 29 to go over the recent