in VIVO: CRISPR/Cas9 used to modify expression of a number of genes in prostate cancer

[Maxone73]

Ok, nowadays I tend to post most preclinical research in Fight Prostate Cancer community, but this is too good:

biosignaling.biomedcentral....

works on cells and on mice models, basically (in a very small nutshell) switching on/off few genes can kill cancer. The fact that it works in vivo with human xenograft models is already promising, but of course this must translate to a clinical trial in the near future.

Adding the fact that another group of researchers found a way to deliver genetic therapy without passing through the liver (that tends to block such therapies) and were able to implant the gene of a cow in mice, creating mice that had twice the muscle mass of normal mice (I talked about this in the other community), I can see some synergistic effect!

[KocoPr]

That is the most indepth article on history of CRISPR/Cas9 and absolutely fascinating how theyare using it against many different PCa pathways. I have been reading it for 30 minutes and looked to see how much more was left to read snd i was only 1/8th of the way through article.

This article is a definite keeper!

Thanks MAX