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Levodopa
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Medication Management
Which brings me to my point.....given the often-stated link between long term
Levodopa
use and dyskinesia, and the lack of impact these meds [u]may[/u] have had for me, I have been giving some serious thought to reducing C/L dose, then if no impact, considering eliminating.
Which brings me to my point.....given the often-stated link between long term
Levodopa
use and dyskinesia, and the lack of impact these meds [u]may[/u] have had for me, I have been giving some serious thought to reducing C/L dose, then if no impact, considering eliminating.
AndyMu72
in
Cure Parkinson's
1 year ago
Review of Genetic and Gene Therapy for Parkinson’s Disease
Under treatment, the primary and major treatment is to be done with
levodopa
preparations.
Levodopa
preparations give adverse effects with increased titer doses. In combination with
levodopa
, MAO-B inhibitors and anticholinergics are also given depending on the symptoms of the disease.
Under treatment, the primary and major treatment is to be done with
levodopa
preparations.
Levodopa
preparations give adverse effects with increased titer doses. In combination with
levodopa
, MAO-B inhibitors and anticholinergics are also given depending on the symptoms of the disease.
Farooqji
in
Cure Parkinson's
1 year ago
blood sugar levels
I read that
levodopa
carbadopa increases your blood level of glucose does anyone take any non-dopamine therapy that works when I take levadopa I can’t stand up. And all of my te tendons, get weak and burn. I also have Lyme disease I’ll read that to her and dopamine enhance Lyme disease.
I read that
levodopa
carbadopa increases your blood level of glucose does anyone take any non-dopamine therapy that works when I take levadopa I can’t stand up. And all of my te tendons, get weak and burn. I also have Lyme disease I’ll read that to her and dopamine enhance Lyme disease.
Marcia123
in
Cure Parkinson's
1 year ago
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amantadine
Dr added to carbo-
levodopa
for HwP..
Dr added to carbo-
levodopa
for HwP..
fel3k
in
Cure Parkinson's
1 year ago
Minimum of 70 mg Carbidopa daily???
https://www.pdr.net/drug-summary/Sinemet-CR-carbidopa-
levodopa
-389.1769 Does anyone know the reason and possibly the link of the medical justification for this recommendation? Merci 🍀
https://www.pdr.net/drug-summary/Sinemet-CR-carbidopa-
levodopa
-389.1769 Does anyone know the reason and possibly the link of the medical justification for this recommendation? Merci 🍀
Esperanto
in
Cure Parkinson's
2 years ago
Gender Differences in Levodopa Pharmacokinetics in Levodopa-Naïve Patients With Parkinson’s Disease
The differences in plasma LD concentrations between men and women over time. Original research article Front. Med., 31 May 2022
https://www.frontiersin.org/articles/10.3389/fmed.2022.909936/full
On my search for the Pharmacokinetics, pharmacodynamics of the various C/L medications, I came
The differences in plasma LD concentrations between men and women over time. Original research article Front. Med., 31 May 2022
https://www.frontiersin.org/articles/10.3389/fmed.2022.909936/full
On my search for the Pharmacokinetics, pharmacodynamics of the various C/L medications, I came
Esperanto
in
Cure Parkinson's
1 year ago
Zandopa and insomnia?
Has anyone found that zandopa causes insomnia, more so than prescription carbidopa
levodopa
or other forms of Mucuna?I have only tried zandopa a few times, but it seems that both times I had some wicked insomnia.
Has anyone found that zandopa causes insomnia, more so than prescription carbidopa
levodopa
or other forms of Mucuna?I have only tried zandopa a few times, but it seems that both times I had some wicked insomnia.
Fireside15
in
Cure Parkinson's
1 year ago
GABA Nutrientsupplement vs Gabapentin and other Prescription Drugs of the same order
The first medication was
Levodopa
100mg as usual. After about 2 years it didn‘t do anything for me anymore. My new medication was Pramipexol 0.088 mg, which for 6 months worked OK. Then continuesly insomnia set in and I was sleeping or better just dosing off for 1-2 h at night .
The first medication was
Levodopa
100mg as usual. After about 2 years it didn‘t do anything for me anymore. My new medication was Pramipexol 0.088 mg, which for 6 months worked OK. Then continuesly insomnia set in and I was sleeping or better just dosing off for 1-2 h at night .
Ohmg
in
Restless Legs Syndrome
1 year ago
spasms
I am on muscle relaxants and tramadol for pain and carbidopa/
levodopa
for Pakinson like symptoms, none of which helped 2 nights ago and I ended up falling hitting my back and the back of my head. Last night I had severe spasms and went to ER.
I am on muscle relaxants and tramadol for pain and carbidopa/
levodopa
for Pakinson like symptoms, none of which helped 2 nights ago and I ended up falling hitting my back and the back of my head. Last night I had severe spasms and went to ER.
horseandwolf
in
PSP Association
1 year ago
carbidopa, levodopa and anal/rectal pain
I know this might be a little bit of TMI for some of you, but I have to know if anyone of you out there has ever experienced severe anal/rectal pain from using carbidopa
levodopa
? Especially from the time you take it until the time it seems to start to work?
I know this might be a little bit of TMI for some of you, but I have to know if anyone of you out there has ever experienced severe anal/rectal pain from using carbidopa
levodopa
? Especially from the time you take it until the time it seems to start to work?
MissRita
in
Cure Parkinson's
1 year ago
How to reduce prolactin and increase AR success/longevity? L-Dopa and Vitex Berry?
Cabergoline reduces prolactin, which promotes prostate cancer mutation and growth. If a doctor will not prescribe Cabergoline, then would Mucuna (natural L-Dopa) extract and Vitex Berry extract have the same effectiveness as the cabergoline, in targeting and reducing prolactin? I recall someone on
Cabergoline reduces prolactin, which promotes prostate cancer mutation and growth. If a doctor will not prescribe Cabergoline, then would Mucuna (natural L-Dopa) extract and Vitex Berry extract have the same effectiveness as the cabergoline, in targeting and reducing prolactin? I recall someone on
GeorgeGlass
in
Advanced Prostate Cancer
1 year ago
PD-related acronyms
BBB = Blood Brain Barrier CD = Carbidopa CD/LD = Comination of carbidopa and
levodopa
C/L = Carbidopa/
levodopa
CNS = Central Nervous System CR = Controlled Relase DA = Dopamine agonist DBS = Deep-brain stimulation DX = Diagnosis ER = Extended Release ET = Essential tremor Hcl = hydrochloride
BBB = Blood Brain Barrier CD = Carbidopa CD/LD = Comination of carbidopa and
levodopa
C/L = Carbidopa/
levodopa
CNS = Central Nervous System CR = Controlled Relase DA = Dopamine agonist DBS = Deep-brain stimulation DX = Diagnosis ER = Extended Release ET = Essential tremor Hcl = hydrochloride
Bennorca
in
Cure Parkinson's
2 years ago
COMT inhibitors
Hubby is doing really well at the moment and I think one of the things that has helped has been the introduction of 1/2 a entacapone tablet taken at the same time as his madopar/ mucuna doses. According to his genetic report his COMT appeared to be one thing that was functioning normally so I was a
Hubby is doing really well at the moment and I think one of the things that has helped has been the introduction of 1/2 a entacapone tablet taken at the same time as his madopar/ mucuna doses. According to his genetic report his COMT appeared to be one thing that was functioning normally so I was a
LAJ12345
in
Cure Parkinson's
1 year ago
Ashwagandha for Parkinson's Symptoms?
www.ncbi.nlm.nih.gov/pmc/articles/PMC10147008/ https://acrobat.adobe.com/id/urn:aaid:sc:US:462498b0-b51b-4ccb-8fbe-4ee37f227272 https://mbdhwellness.com/blogs/all-posts/what-are-the-effects-of-ashwagandha-on-serotonin-and-dopamine https://hellopharmacist.com/questions/is-it-safe-to-take-ashwaganda-with-carbidopa-
levodopa
www.ncbi.nlm.nih.gov/pmc/articles/PMC10147008/ https://acrobat.adobe.com/id/urn:aaid:sc:US:462498b0-b51b-4ccb-8fbe-4ee37f227272 https://mbdhwellness.com/blogs/all-posts/what-are-the-effects-of-ashwagandha-on-serotonin-and-dopamine https://hellopharmacist.com/questions/is-it-safe-to-take-ashwaganda-with-carbidopa-
levodopa
pdpatient
in
Cure Parkinson's
9 months ago
Mucuna-Pruriens
https://www.nutrivitashop.com/l-dopa-100-pure-
levodopa
-mucuna-pruriens-dopamine/ I suggest people with stiffness and rigidity must try this. SPEAKING WITH PERSONAL EXPERIENCE good luck
https://www.nutrivitashop.com/l-dopa-100-pure-
levodopa
-mucuna-pruriens-dopamine/ I suggest people with stiffness and rigidity must try this. SPEAKING WITH PERSONAL EXPERIENCE good luck
sammytoronto93
in
Cure Parkinson's
1 year ago
Levodopa ER before bed?
New prescription is (1) ER 25/100
levodopa
before bed, (1) entacapone & (1) 25/250
levodopa
upon rising, (1) entacapone & (1) 25/100
levodopa
at 11am, (1) 25/100
levodopa
at 2pm, and (1) entacapone & (1) 25/100
levodopa
at 5pm. Total
levodopa
is now 650mg/day.
New prescription is (1) ER 25/100
levodopa
before bed, (1) entacapone & (1) 25/250
levodopa
upon rising, (1) entacapone & (1) 25/100
levodopa
at 11am, (1) 25/100
levodopa
at 2pm, and (1) entacapone & (1) 25/100
levodopa
at 5pm. Total
levodopa
is now 650mg/day.
Zardoz
in
Cure Parkinson's
2 years ago
Interesting Gender Research Findings RE: Levodopa Absorption Rates
Another interesting finding by Contin et al (2022) found a 20% higher absorption of
levodopa
in patients treated with
levodopa
/benserazide versus
levodopa
/carbidopa formulation. These are all important findings for women with Parkinson's.
Another interesting finding by Contin et al (2022) found a 20% higher absorption of
levodopa
in patients treated with
levodopa
/benserazide versus
levodopa
/carbidopa formulation. These are all important findings for women with Parkinson's.
BeedieBird
in
Cure Parkinson's
1 year ago
Fast acting Levodopa?
My understanding is that
levodopa
needs to reach and be absorbed in the small intestine, so the drug needs much time to kick in. There are times however, when the
levodopa
is needed right away. Does anyone recall the post to have thoughts about getting
levodopa
absorbed faster?
My understanding is that
levodopa
needs to reach and be absorbed in the small intestine, so the drug needs much time to kick in. There are times however, when the
levodopa
is needed right away. Does anyone recall the post to have thoughts about getting
levodopa
absorbed faster?
Zardoz
in
Cure Parkinson's
2 years ago
Edited: PD increases chance of RLS.(yes) Azilect worsens RLS.(wrong) Ambroxol, being an antihistamine I believe worsens RLS.(incorrect)
Levodopa
increases augmentation meaning it makes RLS worse. So thinking Azilect does was not necessarily incorrect. If you have PD and develop RLS, well, it is horrid.
Levodopa
increases augmentation meaning it makes RLS worse. So thinking Azilect does was not necessarily incorrect. If you have PD and develop RLS, well, it is horrid.
Little_apple
in
Cure Parkinson's
1 year ago
Phase 2b: Trial of Mesdopetam for Levodopa-induced Dyskinesia Nears End
https://parkinsonsnewstoday.com/news/trial-mesdopetam-
levodopa
-induced-dyskinesia-nears-end/ Mesdopetam is designed to block a dopamine receptor protein called D3 receptor, whose levels are increased in motor-related brain regions with prolonged
levodopa
treatment and associated dyskinesia.
https://parkinsonsnewstoday.com/news/trial-mesdopetam-
levodopa
-induced-dyskinesia-nears-end/ Mesdopetam is designed to block a dopamine receptor protein called D3 receptor, whose levels are increased in motor-related brain regions with prolonged
levodopa
treatment and associated dyskinesia.
Hidden
in
Cure Parkinson's
2 years ago
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