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PSA-Nadir vs Testosterone-Nadir comparing Non-CRPC to CRPX men
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA-Nadir vs Testosterone-Nadir
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
janebob99
in
Prostate Cancer Network
6 months ago
Joint pain
Hi I have a history of back pain due to bulges bit more recently joint pain in lower back. The consultant has said some degeneration found but everyone has that. We are now looking at more spinal injections and further treatment.I am in perimenopause and have been on hrt for 2 years. Everol Patches and
Hi I have a history of back pain due to bulges bit more recently joint pain in lower back. The consultant has said some degeneration found but everyone has that. We are now looking at more spinal injections and further treatment.I am in perimenopause and have been on hrt for 2 years. Everol Patches and
AMS_1
in
Menopause and Perimenopause Support
6 months ago
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ADT response and questions for MO
Hi, I am newish to this forum, still on a steep learning curve but I want to thank you for your contributions and discussions. This is my first time posting. My partner is 60 yrs old, as I understand it he had low PSA 3 yrs ago, not tested until Nov 2023, PSA50, stage 4, 1 met in 'sit' bone. Started
Hi, I am newish to this forum, still on a steep learning curve but I want to thank you for your contributions and discussions. This is my first time posting. My partner is 60 yrs old, as I understand it he had low PSA 3 yrs ago, not tested until Nov 2023, PSA50, stage 4, 1 met in 'sit' bone. Started
Lovecherries
in
Advanced Prostate Cancer
6 months ago
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
Exrunner
in
Advanced Prostate Cancer
6 months ago
New study validates intermittent hormone therapy
PCRI just posted a new video titled 'New study validates intermittent hormone therapy'. So, just search 'PCRI' in YouTube and that video will pop up. Certain individuals on this site feel strongly against curtailing the duration of hormone therapy from the standard 2 to 3 years or even longer. I urge
PCRI just posted a new video titled 'New study validates intermittent hormone therapy'. So, just search 'PCRI' in YouTube and that video will pop up. Certain individuals on this site feel strongly against curtailing the duration of hormone therapy from the standard 2 to 3 years or even longer. I urge
John347
in
Advanced Prostate Cancer
6 months ago
ARASENS Darolutamide vs Placebo
This Kaplan-Meier plot show the Castration - Resistant Prostate Cancer Free survival probability (%) for two groups: (A)
Darolutamide
+ ADT + Docetaxel, versus (B)
Placebo
+ ADT + Docetaxel, taken at two different times: 2 years and 4 years. There is a very large increase in survival
This Kaplan-Meier plot show the Castration - Resistant Prostate Cancer Free survival probability (%) for two groups: (A)
Darolutamide
+ ADT + Docetaxel, versus (B)
Placebo
+ ADT + Docetaxel, taken at two different times: 2 years and 4 years. There is a very large increase in survival
janebob99
in
Advanced Prostate Cancer
6 months ago
ARASENS TRIAL: Darolutamide
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide + ADT + Docetaxel, versus (B) Placebo + ADT + Docetaxel. There is a very large increase in survival probability with the Darolutamide group (A) vs Placebo group
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide + ADT + Docetaxel, versus (B) Placebo + ADT + Docetaxel. There is a very large increase in survival probability with the Darolutamide group (A) vs Placebo group
janebob99
in
Advanced Prostate Cancer
6 months ago
ADT with radiation?
I have a G 4+3, considered to be unfavorable intermediate risk, but a Decipher score of .4, considered to be low risk. I have opted to have radiation to treat my PCa. Do I need to take ADT with the radiation therapy? My MO suggested 4 to 6 months of Orgavix (not sure if I'm spelling it correctly). If
I have a G 4+3, considered to be unfavorable intermediate risk, but a Decipher score of .4, considered to be low risk. I have opted to have radiation to treat my PCa. Do I need to take ADT with the radiation therapy? My MO suggested 4 to 6 months of Orgavix (not sure if I'm spelling it correctly). If
CBRD
in
Advanced Prostate Cancer
6 months ago
still unsure about hysterectomy, been waiting over 1 year for op date, and taken a year to see consultant for a discussion
Was diagnosed with deep filtrating endometriosis and adenomyosis in 2019 following an MRI, and I am now awaiting a laporoscopy (been waiting over a year) and want to be under anaesthetic for that experience. Having a mirena coil was a positive thing for me, as stopped alot of the pain and heaviness of
Was diagnosed with deep filtrating endometriosis and adenomyosis in 2019 following an MRI, and I am now awaiting a laporoscopy (been waiting over a year) and want to be under anaesthetic for that experience. Having a mirena coil was a positive thing for me, as stopped alot of the pain and heaviness of
coletteholt
in
Endometriosis UK
6 months ago
life Insurance
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
JDKotter
in
Advanced Prostate Cancer
6 months ago
Fed up at not being able to do basic stuff
Over last 2 years health wise gonw bad to worse. No energy little interest i. Going out or even getting dressed.I used to be very i dependent ie own diy. Cleani g shoppi g ect. Even had craft hobby.but now all i seemto want to do is sleep
Over last 2 years health wise gonw bad to worse. No energy little interest i. Going out or even getting dressed.I used to be very i dependent ie own diy. Cleani g shoppi g ect. Even had craft hobby.but now all i seemto want to do is sleep
lizaspo
in
British Liver Trust
8 months ago
ISO a third MO opinion for my dad
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Dsmejkal88
in
Advanced Prostate Cancer
6 months ago
Dr Dipnarine Maharaj Immune Regenerative Medicine in Boynton Beach FL
Has anyone heard of him? I am about to start ADT and salvage radiation in 2 months (PSA 0.052) . So in mean time I was going to check him out and wondered if anyone who does a ton of research has heard of him?
Has anyone heard of him? I am about to start ADT and salvage radiation in 2 months (PSA 0.052) . So in mean time I was going to check him out and wondered if anyone who does a ton of research has heard of him?
Peppertree602
in
Advanced Prostate Cancer
6 months ago
PSA doubled in last 30 days after 4 months stable since Provenge. What's next?
Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing quick. I have been off of all ADT since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA
Update: PSA remained roughly 1.7 to 1.8 for last 4 months after Provenge but yesterday's 30-day PSA test revealed a jump to 3.190 so something is growing quick. I have been off of all ADT since finishing fourth LU-177 injection five months ago and one SBRT treatment 4 months ago. After LU-177, PSA
SViking
in
Advanced Prostate Cancer
6 months ago
my first post
Hello there, I’ve been dealing with this since 1/2015. I’ve had brachytherapy, chemotherapy, hormone therapy, cyber knife, immunotherapy, more chemotherapy, now taking Everolimus and letrozole. I’ve always felt that this was a chronic disease after the medications stopped working onto the next regimen
Hello there, I’ve been dealing with this since 1/2015. I’ve had brachytherapy, chemotherapy, hormone therapy, cyber knife, immunotherapy, more chemotherapy, now taking Everolimus and letrozole. I’ve always felt that this was a chronic disease after the medications stopped working onto the next regimen
Sabrina02
in
SHARE Uterine Cancer Support
6 months ago
To those newly diagnosed! There is hope!
I was diagnosed with Parkinson’s in Dec 2018. My form of Parkinson’s has a huge psychological element that many of you can relate to. It’s obvious because of how quickly I progressed while I was getting diagnosed . My Dad who was my best friend and business partner died unexpectedly in 2013, which destroyed
I was diagnosed with Parkinson’s in Dec 2018. My form of Parkinson’s has a huge psychological element that many of you can relate to. It’s obvious because of how quickly I progressed while I was getting diagnosed . My Dad who was my best friend and business partner died unexpectedly in 2013, which destroyed
38yroldmale
in
Cure Parkinson's
10 months ago
PSA vs Testosterone Nadir for CRPC and Non-CRPC
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
janebob99
in
Advanced Prostate Cancer
6 months ago
Can anyone help me please.....
Hi, can anyone help me with these test results please.I have Graves disease, Anemia, pernicious anemia, vitamin D deficiency and various other ailments, but I have been in remission from my graves for at least 5 years. I have been symptomatic a few times but it seems to correct itself, however my hubby
Hi, can anyone help me with these test results please.I have Graves disease, Anemia, pernicious anemia, vitamin D deficiency and various other ailments, but I have been in remission from my graves for at least 5 years. I have been symptomatic a few times but it seems to correct itself, however my hubby
Loza73
in
Thyroid UK
6 months ago
Help for a newbie at start of journey
Hi there. Just joined the forum and its a fantastic source of information - thank you. Was just diagnosed with hypothyroid a week ago after 4 years of feeling totally wiped out so trying to get to grips with it all and can see from the forum its a bit of a journey to try to get well again. Would appreciate
Hi there. Just joined the forum and its a fantastic source of information - thank you. Was just diagnosed with hypothyroid a week ago after 4 years of feeling totally wiped out so trying to get to grips with it all and can see from the forum its a bit of a journey to try to get well again. Would appreciate
Irish_Gal
in
Thyroid UK
6 months ago
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