Experiences with

Hyperthermia therapy

A new research from Oslo University focuses on a new combination therapy for prostate cancer that uses a checkpoint inhibitor and an IRE1 blocker called MKC8866. The therapy works by blocking the IRE1 signaling pathway, which in turn reduces immunosuppressive effects in the tumor microenvironment and

Anyone seen this? This is what JSBMD is talking about https://pmc.ncbi.nlm.nih.gov/articles/PMC11083272/#sec6-ijms-25-04643 Conclusions TH inhibitors down-regulate DA levels and protect DA neurons, while DA receptor agonists function to activate post-synaptic DA receptors to alleviate PD symptoms

Can this be treated with targeted therapy such as Herceptin ( I am not aware of the presence of HER 2 ) but have been told that the surgical option would kill my husband who is 75 yrs old even though CT scan shows no spread . He has not had a PET scan.

Why: We know that leriglitazone/MIN-102 is effective at slowing the progression of AMN and greatly reducing the risk of cerebral involvement, but unless I'm missing something, it's not available to me here in the US currently. But its prodrug, pioglitazone, is, and given that leriglitazone is one of

My daughter has been diagnosed with ADHD. She was born premature at 1lb 1/2. We had to put her in speech therapy. What I later t learned on my own was that although she’s 13 YOA, psychologically and emotionally she’s 8-9 YOA. I was treating her like a 13 year old but then learned this when I found myself

Your Address line 1 Your Address line 2 Your Address line 3 Your Post Code Dr. name here Surgery name Address line 1 Address line 2 Address line 3 Dr.s Post Code Dear Doctor (insert Dr’s name here) [u]Refusal to prescribe liothyronine (T3)[/u] [u]Use of liothyronine (T3) in

Hello, I posted sometime ago. I live in Spain where I had a second thyroid ablation because of hyperthyroidism/Graves’ disease back in March 2024, the first being a year earlier. I then became hypothyroid some time in June/July and started at 75mgs of eutirox which was increased to 88mgs @ end August

Small study but clinical. I don't even know if it could be called phase 1, but at least on humans. The study, published in Cell Reports Medicine, focuses on a new treatment combining pembrolizumab with standard chemotherapy to treat small cell bladder cancer and small cell/neuroendocrine prostate cancer

I have MS fatigue/cog fog (diagnosed in Aug 2009 refused those treatments cause I hate Rx drugs) and functioned the best I could for a few years. Then had a small relapse, the flu, some female health issues and general exhaustion (post viral fatigue) that lasted for months. Lost my job and ended up moving

...but I felt like sharing this!We start having the technology to deliver gene therapy...if we start also having a better idea about how our own cells works we get better and better https://scitechdaily.com/astonishing-scientists-unveil-first-blueprint-of-the-most-complex-molecular-machine-in-human-biology

hi all, Am reading a lot in other forums about red light therapy for male & female partners in infertility, to help cellular regeneration. I knew it was supposed to be good in a led face mask but is it going to help my old ovaries too? ;)

My daughter 22 fell ill with encephalitis in July this year. She responded very well to IVIG and steroids for 5 days. She left hospital feeling well enough to return to Uni and work. She has autoimmune encephalitis seronegative. In late August she deteriorated and returned to hospital in September

HelloI was doing very well with colestyramine and Dermacool cream to treat my subcutaneous itching but it has returned with a vengeance. It's almost intolerable and severely affects my life and sleep. Frankly it is just making me cry most days. Has anyone tried light therapy for this? If so does it work

Hi can anyone recommend any consultants in London for managing urinary incontinence? We are looking to go private because we have had appointment after appointment in Brighton and its such a long wait and my son is getting older (now 10 years old). He has giggle incontinence in the day and bedtime wetting

"The JAK2 V617F mutation is the most common driver gene in myeloproliferative neoplasm (MPN), which means that the JAK/STAT signaling pathway is persistently activated independent of cytokines, and plays an important part in the onset and development of MPN. The JAK inhibitors, although widely used in

https://youtu.be/AF9B-7lv5BQ Skip and Mariana share their emotional and informative journey through Skip's prostate cancer diagnosis and treatment decisions. The couple discusses their experience with proton therapy, the role of military healthcare, the financial implications of treatment, and the crucial

https://youtu.be/AF9B-7lv5BQ Skip and Mariana share their emotional and informative journey through Skip's prostate cancer diagnosis and treatment decisions. The couple discusses their experience with proton therapy, the role of military healthcare, the financial implications of treatment, and the crucial

brachytherapy with proton therapy OR Radical Prostatectomy for intraductal cribriform pattern cancer Gleason 4+3=7

The study aimed to address the challenge of increasing response rates of immune checkpoint inhibitors in mCRPC. ESK981 was chosen for its potential to enhance immunotherapeutic responses. Trial Design and Objectives The trial involved administering ESK981 orally daily for five days, followed by a two-day

[i]Katie Tinkler, who is taking part in the trial at University College Hospital in London, said the treatment could be “life-changing”[/i] [i]LUCY NORTH/PA[/i] Lupus patients given hope of remission in groundbreaking trial Three patients with the condition, which can cause severe joint pain