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Importance of ADT
Are there any good outcomes without using ADT ( hormone therapy)? I delayed it for a couple of years with bad results. My history -- [u]
2021
[/u]: Age 78. PSA was 7.79, Gleason 4+3=7. Small lesion in prostate, with perineural invasion. Had 20 IMRT for prostate. No ADT. [u]
2022
[/u]: PSA
Are there any good outcomes without using ADT ( hormone therapy)? I delayed it for a couple of years with bad results. My history -- [u]
2021
[/u]: Age 78. PSA was 7.79, Gleason 4+3=7. Small lesion in prostate, with perineural invasion. Had 20 IMRT for prostate. No ADT. [u]
2022
[/u]: PSA
vintage42
in
Advanced Prostate Cancer
8 months ago
Restless legs.
I have severe restless legs, as previously discussed within this forum. Over the past few years intercourse has become quite painful - middle age woman syndrome. Recently my GP started me on 10 milligrams estradiol vagifem pessaries. I understand that hrt has a significant impact on rls. My rls was
I have severe restless legs, as previously discussed within this forum. Over the past few years intercourse has become quite painful - middle age woman syndrome. Recently my GP started me on 10 milligrams estradiol vagifem pessaries. I understand that hrt has a significant impact on rls. My rls was
Trish8433
in
Restless Legs Syndrome
9 months ago
Recurrence after prostatectomy
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
Fred312
in
Advanced Prostate Cancer
9 months ago
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fed up of feeling so rubbish!!
Following up from previous posts: Brief history : diagnosed with hypothyroidism in March after going to the DRs initially thinking my HRT needed tweaking, awful brain fog, hair loss, brittle peeling ridged nails, cold feet but extreme sweating at times incl night sweats, dry flaky skin, horrible joint
Following up from previous posts: Brief history : diagnosed with hypothyroidism in March after going to the DRs initially thinking my HRT needed tweaking, awful brain fog, hair loss, brittle peeling ridged nails, cold feet but extreme sweating at times incl night sweats, dry flaky skin, horrible joint
Vorney
in
Thyroid UK
9 months ago
ADT working mechanism
I was just wondering, I heard dr. Richard Joel Wassersug Saying that ADT works well and better if you continue with it but if you start and stop, start and stop, it doesn’t work as well. Did all of you from your own experiences found this to be the case based on your experiences? Thanks for any feedback
I was just wondering, I heard dr. Richard Joel Wassersug Saying that ADT works well and better if you continue with it but if you start and stop, start and stop, it doesn’t work as well. Did all of you from your own experiences found this to be the case based on your experiences? Thanks for any feedback
Ahk1
in
Advanced Prostate Cancer
9 months ago
thrombotic thrombocytopenic purpura (TTP)
Warriors: Recently, I posted about 1 year side effects. Thank you for all of your responses. My SEs got the best of me and I’m writing from a hospital bed. The current theory is I have TTP, which is associated with hormonal therapy. I wanted to write and see if any of you have had the misfortune
Warriors: Recently, I posted about 1 year side effects. Thank you for all of your responses. My SEs got the best of me and I’m writing from a hospital bed. The current theory is I have TTP, which is associated with hormonal therapy. I wanted to write and see if any of you have had the misfortune
TMcgee
in
Advanced Prostate Cancer
9 months ago
Changing thyroid treatment and Testogel
Hi, I wonder if anyone can advise and apologies in advance for the long story! I consulted a private Endocrinologist and started taking Liothyronine in early October 1 x 5mg tablet 3 times a day. I was also on 25mg levothyroxine, 4pumps of estrogel, 2 tablets of progesterone and 1/8 pack of testogel
Hi, I wonder if anyone can advise and apologies in advance for the long story! I consulted a private Endocrinologist and started taking Liothyronine in early October 1 x 5mg tablet 3 times a day. I was also on 25mg levothyroxine, 4pumps of estrogel, 2 tablets of progesterone and 1/8 pack of testogel
Blu-cat11
in
Thyroid UK
9 months ago
Adenomyosis, should I have hysterectomy?
The short version is that I have adenomyosis. I've always had heavy periods with period pains that make my thighs numb and require prescription painkillers. At the age of 44 I had some symptoms of perimenopause and tried HRT. After two years I came off and that seems to have triggered a strong reaction
The short version is that I have adenomyosis. I've always had heavy periods with period pains that make my thighs numb and require prescription painkillers. At the age of 44 I had some symptoms of perimenopause and tried HRT. After two years I came off and that seems to have triggered a strong reaction
mavenmi
in
Endometriosis UK
9 months ago
Prostate cancer treatment and IBS
Dear Friends and Sufferers! I've been diagnosed with prostate cancer and have the option of removing the prostate or radiotherapy with or without hormone treatment. Can anyone out there who has experience of these offer advise on their impact on IBS and bowel function? At the moment, I've got IBS looseness
Dear Friends and Sufferers! I've been diagnosed with prostate cancer and have the option of removing the prostate or radiotherapy with or without hormone treatment. Can anyone out there who has experience of these offer advise on their impact on IBS and bowel function? At the moment, I've got IBS looseness
merve1
in
IBS Network
9 months ago
Soy concerns
Hi, I have been focusing on the nutrition posts to improve my diet as I have osteopenia. I am reading a lot of posts and articles saying to incorporate soy. I stay away from soy because of breast cancer risks. I don't have breast cancer but avoid any estrogen enhancing products/medication like hormone
Hi, I have been focusing on the nutrition posts to improve my diet as I have osteopenia. I am reading a lot of posts and articles saying to incorporate soy. I stay away from soy because of breast cancer risks. I don't have breast cancer but avoid any estrogen enhancing products/medication like hormone
Truth-seeker1951
in
Bone Health and Osteoporosis UK
9 months ago
Radiation and diarrhea/ GI issues/ please help
looking for other experiences with radiation. My dad just went through -4.5 weeks of radiation. I believe it was standard radiation EBRT or IMRT not sure which. It was fine at first, no side effects. By week 4 the side effects started - diarrhea, constipation, abdominal discomfort, gas. He is so uncomfortable
looking for other experiences with radiation. My dad just went through -4.5 weeks of radiation. I believe it was standard radiation EBRT or IMRT not sure which. It was fine at first, no side effects. By week 4 the side effects started - diarrhea, constipation, abdominal discomfort, gas. He is so uncomfortable
alysona828
in
Advanced Prostate Cancer
7 months ago
Struggling to make the best education choices
Hello, My 6-year-old son was diagnosed with ADHD about a year ago. Because of his age, we tried PCIT behavior therapy and while we saw some mild improvements there was no real change. I have homeschooled my son since he was 3. It started off as preschool working on language development in conjunction
Hello, My 6-year-old son was diagnosed with ADHD about a year ago. Because of his age, we tried PCIT behavior therapy and while we saw some mild improvements there was no real change. I have homeschooled my son since he was 3. It started off as preschool working on language development in conjunction
kt01513
in
CHADD's ADHD Parents Together
1 year ago
Should I have a hysterectomy?
The short version is that I have adenomyosis, but it is well enough managed on zoladex/Tibolone that I'm not having any significant pain and not bleeding enough that it is a problem, but I do have lots of more minor issues and my consultant thinks a hysterectomy would be better. I've got the op booked
The short version is that I have adenomyosis, but it is well enough managed on zoladex/Tibolone that I'm not having any significant pain and not bleeding enough that it is a problem, but I do have lots of more minor issues and my consultant thinks a hysterectomy would be better. I've got the op booked
mavenmi
in
Menopause and Perimenopause Support
9 months ago
Adding Docetaxel to T3b?
My husband is 63, stage T3b N0M0. His biopsy showed all 12 cores positive with 80%+ cancer, GL 4+5 with
intraductal carcinoma
and original PSA was 12. According to PSMA pet scan 12 months ago, he has additional risk factors such as
ECE, SVI, PNI
, but no other spread. He has completed 39
My husband is 63, stage T3b N0M0. His biopsy showed all 12 cores positive with 80%+ cancer, GL 4+5 with
intraductal carcinoma
and original PSA was 12. According to PSMA pet scan 12 months ago, he has additional risk factors such as
ECE, SVI, PNI
, but no other spread. He has completed 39
Adendino
in
Advanced Prostate Cancer
8 months ago
The importance of training your legs (if you can, of course)
Engaging in fitness activities is considered a standard of care (SOC) for many cancer patients, not only because it enhances overall health but also due to the chemical interactions between muscles and cancer cells. Comprehensive body training is essential, with an emphasis on targeting the body's largest
Engaging in fitness activities is considered a standard of care (SOC) for many cancer patients, not only because it enhances overall health but also due to the chemical interactions between muscles and cancer cells. Comprehensive body training is essential, with an emphasis on targeting the body's largest
Maxone73
in
Advanced Prostate Cancer
9 months ago
subclinical - do I need levo?
I have been borderline Subclinical hypothyroidism for around 10 years. The GP put me on levothyroxine 2013, I took a low dose for a month or two but couldn’t tolerate it (palpitations), so I stopped. I was referred to Endo who did a check on my antibodies - was clear. Every year, my tsh was either just
I have been borderline Subclinical hypothyroidism for around 10 years. The GP put me on levothyroxine 2013, I took a low dose for a month or two but couldn’t tolerate it (palpitations), so I stopped. I was referred to Endo who did a check on my antibodies - was clear. Every year, my tsh was either just
Rambler16
in
Thyroid UK
9 months ago
Locally Advanced PC - should I accept offer of docetaxel?
Hi I'm UK based, new to Health Unlocked and just starting to get to grips with the chats. I was diagnosed August '23 with locally advanced PV. Spread has occurred to a seminal vesicle and, very slightly, to a pelvic lymph node (Oncologist called it 'subtle') Gleason of 4+5. I immediately embarked
Hi I'm UK based, new to Health Unlocked and just starting to get to grips with the chats. I was diagnosed August '23 with locally advanced PV. Spread has occurred to a seminal vesicle and, very slightly, to a pelvic lymph node (Oncologist called it 'subtle') Gleason of 4+5. I immediately embarked
TsarskoMomche
in
Advanced Prostate Cancer
9 months ago
Androstenedione & Frailty
New study from Spain [1]. For many years, I used a product that probably contained DES (diethylstilbestrol) - perhaps 1 mg? My QoL was very good. When I eventually migrated to 3 mg DES - plus a shot of testosterone cypionate every 3 months - I began to feel frail. The new study associates high
New study from Spain [1]. For many years, I used a product that probably contained DES (diethylstilbestrol) - perhaps 1 mg? My QoL was very good. When I eventually migrated to 3 mg DES - plus a shot of testosterone cypionate every 3 months - I began to feel frail. The new study associates high
pca2004
in
Fight Prostate Cancer
9 months ago
hormonnes .. are they ok or not
have been unwel for over 4 years now I have fibromyalgia since 2014 which I managed fine until 4/5 years ago became increased unwel daily .. have had to leave my job now due to ill health … recently had health check to see if could help as GP kept saying all in my head … results for Hormonnes were as
have been unwel for over 4 years now I have fibromyalgia since 2014 which I managed fine until 4/5 years ago became increased unwel daily .. have had to leave my job now due to ill health … recently had health check to see if could help as GP kept saying all in my head … results for Hormonnes were as
kes2008
in
Menopause and Perimenopause Support
9 months ago
Speechless by my GP’s response
I messaged my GP surgery and requested a full thyroid blood test (not just TSH which is all I’ve been able to get since COVID) as well as iron, vits B and D tests. I’ve been feeling really rotten, and want to look at every potential reason. Now, bear in mind I have been on HRT (prescribed by them) for
I messaged my GP surgery and requested a full thyroid blood test (not just TSH which is all I’ve been able to get since COVID) as well as iron, vits B and D tests. I’ve been feeling really rotten, and want to look at every potential reason. Now, bear in mind I have been on HRT (prescribed by them) for
Partiallythere
in
Thyroid UK
9 months ago
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