Experiences with

Half Sinemet CR

My brother takes Sinemet plus 25mg/100mg tablets - One and a half tablets at 8am, 11am, 2pm, 5pm and 8pm. Half Sinemet CR 25mg/100mg tablets - one taken at bedtime. I have noticed after taking Sinemet plus he is unable to get out of chair or bed for up to an hour, dizziness and sleepiness.

I had PD for 12 years( I am 57 now ),and I was on Sinemet 100/25 mg 1.5 tabs for 3 times a day. Sinemet works really well for me, the morning dose kicks in within 10 minutes and lasts about 2.5 hrs. The next doses take longer to work, but still havre no problem to bring me to the “ON” time . I also had

I am now taking Mirapex as well as Pregabalin for my severe RLS. I had to stop using Sinemet because of the augmentation and now I am beginning to suffer the same with Mirapex. I am having occasional outbreaks of RLS in the afternoons and early evening . I cannot predict when this might occur. It is

I have my daily struggles with my Parkinson’s symptoms and the on and off periods and the precise dosing of my sinemet during the daytime hours to get me through the day but once nighttime comes around my symptoms all but disappear. I’ve had Parkinson’s for close to 25 years and I’ve have never taken

We are on vacation in London (Mayfair) and somehow, I didn’t bring enough Sinemet (25/100) 🙄. I’m hoping to find a doctor to write me a prescription for 5 pills. Does anyone have a suggestion for the best way to go about that? I don’t want to ask the hotel because I’m afraid the doctor will cost way

I met Florinda over a year ago through Young Parkies Portugal. At the time, I was dedicated to promoting the therapy and was helping some people implement the protocol. Some recent experiences had already caught my attention that many people are what I call “low dosers,” meaning they respond to doses

I am having panic attacks every evening and take 45mg of Remeron, 15 mg Buspar x3 plus 2 1/2 tablets of 25/100 Sinemet 6 times a day. My neuro is reducing the Sinemet and won’t do anything about the anxiety. I have a new Psychiatrist that won’t change anything either. My family Dr has given me 30 .25

Hi everybody, I'm a new member Adviced by a friend, I recently discovered this very interesting site and his forum ! Wish to have discovered it earlier !!! First of all, forgive me for my poor english, I live in belgium , I speak french. I'm 77 and suffer from RLS for more or less 35 years ....

I saw a neurologist yesterday for the first time since being diagnosed with PD five years ago. My symptoms started five years prior to that, so I am in my 10th year. I am 71 years old. I have not taken any conventional PD drugs as of yet. Been managing symptoms primarily through exercise, diet and

Good morning, I am looking for other contributors experiences to the B1 Therapy. Especially with the sublingual version. Twice over the last 12 months or so I have reached the same point and I am just wondering how to get beyond it. I seem to reach the sweet spot for the therapy, but this point seems

I have been struggling to find the “sweet spot” with high dose thiamine therapy for almost 2 yrs. Diagnosed with PD for 7 yrs. Main issue is increasing stiffness in both legs. I try to do fast walking every day but it is becoming harder and harder. I have been taking a B-complex from Bronson’s which

I just discovered this wonderful site. I am 69, female, and live in Quebec, Canada. I have had RLS since I my youth and can identify with so many of your struggles. When officially diagnosed in my 20’s, I was prescribed clonazepam which helped for a few years. I then was referred to a neurologist and

My Ferritin level is 126. I thought this was triggering my severe RLS since I had a total knee replacement in November , 2023. My RLS is off the rail . I want an Iron infusion, but the health group I belong to, does not believe I need this? I am traveling the next 2 months, will take Sinemet to use on

I just changed drug regimen from just Sinemet to Sinemet plus Pramipexole. When I am out and about getting 2 pills out is a pain. I asked my Neuro if it was OK to stuff them in a gelcap. She said yes. Is anyone else doing this? Problems? Now to patent it and sell it for 1000 x the cost🤣😂

Hello again. So after a ten-month hiatus after my initial consult, the NHS finally scheduled my LCT. There was only a marginal 'on' benefit. Do we have any idea what the percentage split is between the two outcomes? Thank you.

I tried to search any study but could not find it.

Hi all, I’ve recently been experiencing wearing off symptoms only 2 / 3 hours after taking Sinemet meds. Limbs feel heavy, tremors worse, exhausted as my body is so tense all the time. Sometimes I just try to walk it off, not very successful! The neurologist has upped my dosage to 1x25mg plus 1x12.5mg

My neurologist felt that I was taking too much sinemet.125/100 and cut me back from 8 pills a day to 6 every 3 hours and none at night. I wind up freezing up and can’t move in bed. I live alone and this is impossible. My mornings go fairly well but afternoons I feel I’m almost getting too much.

We're trying to go in the opposite direction of many here by adding Sinemet to Mucuna and are having a heck of a time... it's been exhausting and a little scary. Hoping anyone here can help a bit. For about 6 years now, my partner Jay (diagnosed 2009) has been taking only Mucuna at rather high doses

**Bassofspades** is an active member on HealthUnlocked, particularly in the Cure Parkinson's community. They have shared their personal experiences and thoughts on living with Parkinson's disease. Here are some key points from their posts: 1. **Living with Parkinson's**: Bassofspades emphasizes the