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Anyone has treatment addressing Genomic ATM Mutations?
I have a tier 1 genomic mutation ATM FRAMESHIFT MUTATION Anyone try Provenge? I am trying to found if I should do the drug of the moment suggested to me Keytruda by MSK ARK Inhibitors A Vaccine maybe? I’m in chemotherapy for Liver Mets see bio MSK wants to add Keytruda He said all
I have a tier 1 genomic mutation ATM FRAMESHIFT MUTATION Anyone try Provenge? I am trying to found if I should do the drug of the moment suggested to me Keytruda by MSK ARK Inhibitors A Vaccine maybe? I’m in chemotherapy for Liver Mets see bio MSK wants to add Keytruda He said all
Shorehousejam
in
Advanced Prostate Cancer
3 months ago
Just some new Information about AI
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
chefjlu
in
Advanced Prostate Cancer
6 months ago
Intraductal Prostate Carcinoma
Just wanted to say hello as this is a new journey. Hopefully most of you are experiencing success better than anticipated from the onset. . I share many of your diagnosis but for any of you out there with the more (rare) - intraductal Carcinoma diagnosis I'd love to see if it's possible to connect
Just wanted to say hello as this is a new journey. Hopefully most of you are experiencing success better than anticipated from the onset. . I share many of your diagnosis but for any of you out there with the more (rare) - intraductal Carcinoma diagnosis I'd love to see if it's possible to connect
bdrakes
in
Advanced Prostate Cancer
3 months ago
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InkMune clinical trial goes on: second cohort is being treated
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a biologic therapy In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial. None of the patients who have received INKmune so far have
Maxone73
in
Advanced Prostate Cancer
3 months ago
fatique
diagnosed Dec 2022 with stage IV advanced metastatic prostate cancer spread to most bones primarily spine and pelvis - pelvis area continues to be an issue for me. had 10 quick radiation sessions on some spinal drop tumours the Decatoxel x 10 rounds of chemo, ended May 2023 plus Firmagon (Degarelix
diagnosed Dec 2022 with stage IV advanced metastatic prostate cancer spread to most bones primarily spine and pelvis - pelvis area continues to be an issue for me. had 10 quick radiation sessions on some spinal drop tumours the Decatoxel x 10 rounds of chemo, ended May 2023 plus Firmagon (Degarelix
Nyon
in
Advanced Prostate Cancer
3 months ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
janebob99
in
Advanced Prostate Cancer
6 months ago
PSA vs Testosterone at high T levels - Linear Model
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
This is a plot of PSA versus Testosterone in men with prostate cancer. The blue points are taken from a YouTube video lecture by A. Morgentaler (2020). https://www.youtube.com/watch?v=wafNZV-Hkqk The green point is from Safraidi (2022): https://oamjms.eu/index.php/mjms/article/view/9388 Note the
janebob99
in
Advanced Prostate Cancer
6 months ago
About ATR Inhibitors… I Have a Tier 1 ATM Frameshift Mutation is response better than Keytruda perhaps?
Started Chemotherapy yesterday with Cabazitoxel And Carboplatin For Liver Mets & Lung Nodules I have to have pathology on tissue done for second opinion as I’m not sure if they did a complete staining histology It Thankfully came back as pca Adenocarcinoma Still believe it seeded the liver
Started Chemotherapy yesterday with Cabazitoxel And Carboplatin For Liver Mets & Lung Nodules I have to have pathology on tissue done for second opinion as I’m not sure if they did a complete staining histology It Thankfully came back as pca Adenocarcinoma Still believe it seeded the liver
Shorehousejam
in
Advanced Prostate Cancer
3 months ago
PSMA Scan to be scheduled - thank you Tall Allen
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
Geno2853
in
Advanced Prostate Cancer
6 months ago
A Celebration of Life
Good morning or afternoon! I've mentioned in some other posts that almost 19 years ago I had a liver transplant. I have done well and feel these 19 years added to my life are such a gift. Shortly after I retired from nursing I began volunteering my time at MidAmerica Transplant. This is a local (St
Good morning or afternoon! I've mentioned in some other posts that almost 19 years ago I had a liver transplant. I have done well and feel these 19 years added to my life are such a gift. Shortly after I retired from nursing I began volunteering my time at MidAmerica Transplant. This is a local (St
DonnaBoll
Administrator
in
PBC Foundation
6 months ago
Dermatologist recommendation Sussex, UK
Can anybody recommend a dermatology consultant in Sussex, UK, please? Answers by DM please. Dermatitis, eczema, rosacea, and unknown rash
Can anybody recommend a dermatology consultant in Sussex, UK, please? Answers by DM please. Dermatitis, eczema, rosacea, and unknown rash
JumpJiving
in
MY SKIN
3 months ago
Effects of medications
I was diagnosed with PD about a year ago. I am of course interested in anything that is neuroprotective. I was told that only exercise is so I do that. Some believe that nicotine is so I have been on nicotine gum for several months. So far I have not noticed progression. My primary symptom is weakness
I was diagnosed with PD about a year ago. I am of course interested in anything that is neuroprotective. I was told that only exercise is so I do that. Some believe that nicotine is so I have been on nicotine gum for several months. So far I have not noticed progression. My primary symptom is weakness
lovelabretrievers
in
Cure Parkinson's
6 months ago
Apalutamide/ADT Confers 100% Recurrence-Free Survival in High-Risk Prostate Cancer
https://www.oncnursingnews.com/view/apalutamide-adt-confers-100-recurrence-free-survival-in-high-risk-prostate-cancer So if I have this right high risk patients who got RP are put on adt and apalutamide for 12 months and after two years, now with recovered tst none have had a recurrence. am a little
https://www.oncnursingnews.com/view/apalutamide-adt-confers-100-recurrence-free-survival-in-high-risk-prostate-cancer So if I have this right high risk patients who got RP are put on adt and apalutamide for 12 months and after two years, now with recovered tst none have had a recurrence. am a little
street-air
in
Advanced Prostate Cancer
3 months ago
NCT04662580 - All about ARX517 as Monotherapy
Hello, Tomorrow I am going to participate in ARX517 as Monotherapy. Here is the clinical trial: https://www.clinicaltrials.gov/study/NCT04662580. Share your questions / positive comments. I will update here Special request to
Tall_Allen
- Please tell : what should I ask ? [
Hello, Tomorrow I am going to participate in ARX517 as Monotherapy. Here is the clinical trial: https://www.clinicaltrials.gov/study/NCT04662580. Share your questions / positive comments. I will update here Special request to
Tall_Allen
- Please tell : what should I ask ? [
God_Loves_Me
in
Advanced Prostate Cancer
5 months ago
Two for Chemotherapy, Both My Wife and I, Her with TNBC and Myself now with PCA Liver Mets
Today is Two for Chemotherapy My wife discovered a lump in her breast in November2023, called for mammogram and they, Montefiore NY, made her wait to January 16th, of course she didn’t know TNBC grows at approximately 1% a day. So, January 16th, they did Mammogram, MRI, Ultrasound and Biopsy.
Today is Two for Chemotherapy My wife discovered a lump in her breast in November2023, called for mammogram and they, Montefiore NY, made her wait to January 16th, of course she didn’t know TNBC grows at approximately 1% a day. So, January 16th, they did Mammogram, MRI, Ultrasound and Biopsy.
Shorehousejam
in
Advanced Prostate Cancer
3 months ago
Help to do BAT treatment for my dad. Located in Norway.
Hello everyone! Writing on behalf of my father who is 67 yo and has prostate cancer. We are based in Norway. Prostatectomy done in March -17. Treated with Bicalutamide and Zoladex injection until rise in PSA 18 months ago. Increasing PSA from 6-12 on chemotherapy through last summer. September he was
Hello everyone! Writing on behalf of my father who is 67 yo and has prostate cancer. We are based in Norway. Prostatectomy done in March -17. Treated with Bicalutamide and Zoladex injection until rise in PSA 18 months ago. Increasing PSA from 6-12 on chemotherapy through last summer. September he was
VonKantarellen
in
Advanced Prostate Cancer
6 months ago
Pulmonary Node revealed with PET scan not growing
During my treatment for PC the first Pet scan showed a pulmonary node. There were no Mets beyound the prostate. Three DRs., Urologist, Oncologist and Pulmonary, did not attribute the node to the PC, since it was so far removed and there were no other mets revealed. A subsquent MRI 3 months later indicated
During my treatment for PC the first Pet scan showed a pulmonary node. There were no Mets beyound the prostate. Three DRs., Urologist, Oncologist and Pulmonary, did not attribute the node to the PC, since it was so far removed and there were no other mets revealed. A subsquent MRI 3 months later indicated
Eadgbe
in
Advanced Prostate Cancer
3 months ago
Ultrasound-guided microwave ablation (MWA) is a safe, effective method for treating bone metastases
"Metastases were located on the ribs, skull, pelvis, spinal cone, and sternum. Pathological types included sarcomas (32%), adenocarcinomas (32%), squamous carcinomas (24%), and types labeled as “other” (12%). MWA had a technical success rate of 100%, with no severe complications being reported among
"Metastases were located on the ribs, skull, pelvis, spinal cone, and sternum. Pathological types included sarcomas (32%), adenocarcinomas (32%), squamous carcinomas (24%), and types labeled as “other” (12%). MWA had a technical success rate of 100%, with no severe complications being reported among
Maxone73
in
Advanced Prostate Cancer
3 months ago
Reintroduce myself for new members
Hello everyone! Let me introduce myself. My name is Donna Boll. I have been given the wonderful opportunity from The PBC Foundation to facilitate your online support group, Health Unlocked. For the last 6 years I have facilitated an amazing online PBC support group for The American Liver Foundation
Hello everyone! Let me introduce myself. My name is Donna Boll. I have been given the wonderful opportunity from The PBC Foundation to facilitate your online support group, Health Unlocked. For the last 6 years I have facilitated an amazing online PBC support group for The American Liver Foundation
DonnaBoll
Administrator
in
PBC Foundation
6 months ago
Liver Biopsy Back, What does it mean? I don’t know if there will be more information with histology and staining, or if this is all of it
Liver Biopsy 5/6/2024 Core needle biopsy device: Bard Mission Core needle size: 18 gauge Number of core specimens: 6 Samples submitted fresh to tissue bank Surgical PathologyReport Specimen Date: 5/6/2024 In Lab Date: 5/6/2024 11:18 Report Date: 5/9/2024 Patient: Encounter #: Location
Liver Biopsy 5/6/2024 Core needle biopsy device: Bard Mission Core needle size: 18 gauge Number of core specimens: 6 Samples submitted fresh to tissue bank Surgical PathologyReport Specimen Date: 5/6/2024 In Lab Date: 5/6/2024 11:18 Report Date: 5/9/2024 Patient: Encounter #: Location
Shorehousejam
in
Advanced Prostate Cancer
3 months ago
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