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FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
cujoe
in
CLL Support
8 months ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
8 months ago
Diagnosed at 61
I had a my first tonic clonic seizure June 23. I'd been having focal seizures for 10 years but didn't know what they were, so never saw the doctor. I've had CT scan, MRI and all normal. Had an ECT and that showed abnormal electrical activity in my brain which shocked me. I started Lamotrigine in July
I had a my first tonic clonic seizure June 23. I'd been having focal seizures for 10 years but didn't know what they were, so never saw the doctor. I've had CT scan, MRI and all normal. Had an ECT and that showed abnormal electrical activity in my brain which shocked me. I started Lamotrigine in July
TheCoulerPurple
in
Epilepsy Action
5 months ago
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coming off rotigotine patches
Hello, First post… Could someone please share their experience coming off rotigotine patches, and what helped you throughout this experience? Been on rotigotine for 4 or so years, and more recently started experiencing augmentation. Was on 2mg, in August GP suggested increasing to 3mg but that hardly
Hello, First post… Could someone please share their experience coming off rotigotine patches, and what helped you throughout this experience? Been on rotigotine for 4 or so years, and more recently started experiencing augmentation. Was on 2mg, in August GP suggested increasing to 3mg but that hardly
Artifcial
in
Restless Legs Syndrome
8 months ago
Where Are My People?
I was diagnosed with major depressive disorder over 5 years ago. It started with speech therapy but didn’t seem to help. I’ve been medicated since then but it doesn’t feel like it’s doing its job anymore. The last couple years have been a rollercoaster with changing meds multiple times, worsening depression
I was diagnosed with major depressive disorder over 5 years ago. It started with speech therapy but didn’t seem to help. I’ve been medicated since then but it doesn’t feel like it’s doing its job anymore. The last couple years have been a rollercoaster with changing meds multiple times, worsening depression
RottieFlood37
in
Major Depressive Disorder (MDD) Support
8 months ago
hypothyroidism
I am trying to make a change in thyroid medication.....I was trying change over to a natural thyroid and stop my Armour thyroid 90 mcg I was doing good until last month ....got very tired, heart palpitations , joint pain ect.... been trying to get thyroid tested but could not get doctors to do ( long
I am trying to make a change in thyroid medication.....I was trying change over to a natural thyroid and stop my Armour thyroid 90 mcg I was doing good until last month ....got very tired, heart palpitations , joint pain ect.... been trying to get thyroid tested but could not get doctors to do ( long
Spencer7
in
Thyroid UK
5 months ago
COMBINATION THERAPY IS NOW UNDER REVIEW
This review indicates how and why combination therapy may be used in treatment. Interesting in itself, but another example of cherry-picking evidence ( we aren't mentioned in spite of starting this concept in 2012. Good cliquish admission where the "nonprofessionals"are best kept well out of the limelight
This review indicates how and why combination therapy may be used in treatment. Interesting in itself, but another example of cherry-picking evidence ( we aren't mentioned in spite of starting this concept in 2012. Good cliquish admission where the "nonprofessionals"are best kept well out of the limelight
diogenes
in
Thyroid UK
8 months ago
New Consultant-Different Plan
Long story short- long battle to get diagnosis although received in 2019 and Hashimoto’s confirmed. After several attempts to stabilise on mono therapy I was lucky enough after several years of strife and illness to be allocated an endo who listened to me, took cortisol levels (low) addisons test (
Long story short- long battle to get diagnosis although received in 2019 and Hashimoto’s confirmed. After several attempts to stabilise on mono therapy I was lucky enough after several years of strife and illness to be allocated an endo who listened to me, took cortisol levels (low) addisons test (
Lassithi
in
Thyroid UK
6 months ago
some great news….
My son will be turning 4 this January and that in and of itself is great news. Nothing is scarier than having just given birth and not knowing what the future of your precious new child will hold, like simply living. my son was born with PUV and severe reflux bilaterally. Of course there was renal
My son will be turning 4 this January and that in and of itself is great news. Nothing is scarier than having just given birth and not knowing what the future of your precious new child will hold, like simply living. my son was born with PUV and severe reflux bilaterally. Of course there was renal
MotherofBarbearians
in
Parents of Children with Kidney Disease
8 months ago
Made a desicion, went private
I was referred to ENT in November about my goitre by an Anaesthetist. I've been on carbimazole coming up to a year and every single 6 weeks i am over medicated. Stopped meds for 2 weeks, or 6 weeks and hey presto I'm back to severely over. Now hairless. I found the name of the Consultant I'd been referred
I was referred to ENT in November about my goitre by an Anaesthetist. I've been on carbimazole coming up to a year and every single 6 weeks i am over medicated. Stopped meds for 2 weeks, or 6 weeks and hey presto I'm back to severely over. Now hairless. I found the name of the Consultant I'd been referred
TwigwithaWig
in
Thyroid UK
5 months ago
What are the most promising drugs/treatments on the horizon for PD symptom relief,slowing progression?
I see Buntanetap,Celeste light therapy and Cue1 as potentials. anyone have any thoughts? i dont know how much longer I can hang on.
I see Buntanetap,Celeste light therapy and Cue1 as potentials. anyone have any thoughts? i dont know how much longer I can hang on.
Jmellano
in
Cure Parkinson's
8 months ago
Newly diagnosed metastatic PC treatment options
Hi, I'm 68 years old. Here are the key points in my story so far: In July 2023 a blood test showed a PSA value of 45. On September 26 2023, prostate MRI showed a dominant tumor in the prostate with extension into the right seminal vesicle. Also the fat plane between the rectum and prostate is lost
Hi, I'm 68 years old. Here are the key points in my story so far: In July 2023 a blood test showed a PSA value of 45. On September 26 2023, prostate MRI showed a dominant tumor in the prostate with extension into the right seminal vesicle. Also the fat plane between the rectum and prostate is lost
ShorePine
in
Advanced Prostate Cancer
8 months ago
Online/Meet ups for people with Hypertrophic Cardiomyopathy struggling with Mental Health?
Hi everyone, so my partner was diagnosed with HC when he was 14. Been in great shape and only having medication for his condition up until 2016/2017, then 41, he was advised to have an ICD. Since then he's had 3 occasions where the device has delivered shock therapy and unfortunately the last 2 occasions
Hi everyone, so my partner was diagnosed with HC when he was 14. Been in great shape and only having medication for his condition up until 2016/2017, then 41, he was advised to have an ICD. Since then he's had 3 occasions where the device has delivered shock therapy and unfortunately the last 2 occasions
Chunkiedog
in
British Heart Foundation
6 months ago
still here
Hi All I like to try and update my journey so you can see that there are some longer term survivors. I am still on 0 PSA with advanced cancer. My journey is on my bio. I was diagnosed at 47 and now I’m 54 with no progression. My primary treatment was Zytiga and it is still working. I take a concoction
Hi All I like to try and update my journey so you can see that there are some longer term survivors. I am still on 0 PSA with advanced cancer. My journey is on my bio. I was diagnosed at 47 and now I’m 54 with no progression. My primary treatment was Zytiga and it is still working. I take a concoction
Apollo123
in
Advanced Prostate Cancer
7 months ago
Results after T3/T4 trial...is this it?
Hello, Medicheck results after T3/T4 trial since 15/11/23, reduced levo then from 150 to 125, added 5mg T3 23/11/23, red levo to 100mg 06/12/23, added 55mg T3 12/12/23. 30/12/23 not feeling best GP closed added 12.5 levo myself as thought maybe under medicated. Medicheck 08/02/24. T4 16.7
Hello, Medicheck results after T3/T4 trial since 15/11/23, reduced levo then from 150 to 125, added 5mg T3 23/11/23, red levo to 100mg 06/12/23, added 55mg T3 12/12/23. 30/12/23 not feeling best GP closed added 12.5 levo myself as thought maybe under medicated. Medicheck 08/02/24. T4 16.7
Klawd
in
Thyroid UK
6 months ago
Robert
Robert was diagnosed with Parkinson’s in 2018 PSP in 2021 progression was slow at first. Last year Robert was walking with a cane and dragging his feet. In September he began to fall daily sometimes more. He got weaker every day and finally allowed me to call a rescue. What followed was a whirlwind
Robert was diagnosed with Parkinson’s in 2018 PSP in 2021 progression was slow at first. Last year Robert was walking with a cane and dragging his feet. In September he began to fall daily sometimes more. He got weaker every day and finally allowed me to call a rescue. What followed was a whirlwind
Wrski
in
PSP Association
8 months ago
mr. Smith
just got diagnosed with prostate cancer with gleson scale of 8. I have had CAT scan and bone scan, they came back good. My urologist is suggesting surgery or possibly surgery, radiation and hormone therapy. The radiologist says proton or IMTR radiation plus hormone treatment. I have appointment to
just got diagnosed with prostate cancer with gleson scale of 8. I have had CAT scan and bone scan, they came back good. My urologist is suggesting surgery or possibly surgery, radiation and hormone therapy. The radiologist says proton or IMTR radiation plus hormone treatment. I have appointment to
Laguy01
in
Prostate Cancer Network
3 hours ago
What to concentrate on .....
Following on from my last post. https://healthunlocked.com/thyroiduk/posts/151050699/gp-has-concerns-about-results I have a GP appointment next week so, in preparation did a MMH thyroid test and got the results this morning. TSH 0.08 mIU/L (.27 - 4.2) -4.8% Free T4 (fT4) 21.1 pmol/L (12 - 22) 91.0% Free
Following on from my last post. https://healthunlocked.com/thyroiduk/posts/151050699/gp-has-concerns-about-results I have a GP appointment next week so, in preparation did a MMH thyroid test and got the results this morning. TSH 0.08 mIU/L (.27 - 4.2) -4.8% Free T4 (fT4) 21.1 pmol/L (12 - 22) 91.0% Free
Jingley
in
Thyroid UK
14 hours ago
Black cohosh for hot flashes and night sweats
What’s your experience with this herb for night sweats and hot flashes? I’m having more, after 3 months in to adt and Xtandi.
What’s your experience with this herb for night sweats and hot flashes? I’m having more, after 3 months in to adt and Xtandi.
CousinGrandpa
in
Advanced Prostate Cancer
16 hours ago
Treatment Options (Hypo)
There are many different thyroid hormone replacements available globally. There are branded replacements and generic replacements (generics are copies of the original drug). They come in tablets, capsules and liquid form. Some are lactose-free and you can also get some with minimal inactive ingredients
There are many different thyroid hormone replacements available globally. There are branded replacements and generic replacements (generics are copies of the original drug). They come in tablets, capsules and liquid form. Some are lactose-free and you can also get some with minimal inactive ingredients
TUKOffice
Thyroid UK
in
Thyroid UK
17 hours ago
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