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hormone refractory PCa, what next?
I have accepted consultant's offer of 6 rounds of
docetaxel
chemo, starting very shortly, which on average should add 1-2 years to my life. Researching what happens after that, my impression is that, once PCa becomes hormone refractory (i.e.
I have accepted consultant's offer of 6 rounds of
docetaxel
chemo, starting very shortly, which on average should add 1-2 years to my life. Researching what happens after that, my impression is that, once PCa becomes hormone refractory (i.e.
rpol
in
Advanced Prostate Cancer
6 years ago
PC has spread to liver!! NEED a HAIL MARY!!
CT scan this morning showed PC has spread to my husband's liver!! We NEED a HAIL MARY!! -and any words of wisdom that will give more hope We plan to seek additional opinions from other prostate cancer oncologists - any recommendations? (we are currently at U of Chicago) Our oncologist recommends
CT scan this morning showed PC has spread to my husband's liver!! We NEED a HAIL MARY!! -and any words of wisdom that will give more hope We plan to seek additional opinions from other prostate cancer oncologists - any recommendations? (we are currently at U of Chicago) Our oncologist recommends
JLS1
in
Advanced Prostate Cancer
6 years ago
Jevtana [Cabazitaxel] & Androgen Status.
The recent STAMPEDE and CHAARTED trials showed that
docetaxel
in combination with ADT increased survival in hormone sensitive prostate cancer patients, suggesting cross-talk between AR signaling and chemotherapy efficacy.
The recent STAMPEDE and CHAARTED trials showed that
docetaxel
in combination with ADT increased survival in hormone sensitive prostate cancer patients, suggesting cross-talk between AR signaling and chemotherapy efficacy.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
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Seven-Month Prostate-Specific Antigen Is Prognostic in Metastatic Hormone Sensitive Prostate Cancer Treated With Androgen Deprivation With O
But a question that I have is this: did the study keep the patients only on ADT or ADT+
Docetaxel
throughout all the way to the OS event despite progression? I can't see any information on additional treatments - just curious how this number is calculated.
But a question that I have is this: did the study keep the patients only on ADT or ADT+
Docetaxel
throughout all the way to the OS event despite progression? I can't see any information on additional treatments - just curious how this number is calculated.
snoraste
in
Advanced Prostate Cancer
6 years ago
Cancer spread to lungs and lymph nodes
He starts 6 rounds of chemo (
docetaxel
)on 29th Jan. We are in the uk, dad is being treated at Queens hospital in Romford Essex. I'm not really sure what I'm asking but any advice would be great, especially from anyone in a similar position.
He starts 6 rounds of chemo (
docetaxel
)on 29th Jan. We are in the uk, dad is being treated at Queens hospital in Romford Essex. I'm not really sure what I'm asking but any advice would be great, especially from anyone in a similar position.
Clarejb
in
Advanced Prostate Cancer
6 years ago
PSMA Lutetium 177 treatment in Germany
Started hormone treatment (degarelix) same day, and apart from some expected hot flushes, no side effects, so this January, started chemo as well (
docetaxel
).
Started hormone treatment (degarelix) same day, and apart from some expected hot flushes, no side effects, so this January, started chemo as well (
docetaxel
).
Tonyliv
in
Advanced Prostate Cancer
6 years ago
Low testosterone / PSA failure / risk of death.
Given prolonged survival when abiraterone or
docetaxel
is added to ADT in men with castrate-sensitive metastatic PC and possibly localized high-risk PC provides a rationale supporting their use with ADT in men with low testosterone in the setting of a phase 2 trial.
Given prolonged survival when abiraterone or
docetaxel
is added to ADT in men with castrate-sensitive metastatic PC and possibly localized high-risk PC provides a rationale supporting their use with ADT in men with low testosterone in the setting of a phase 2 trial.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Lower Back Pain During Chemo
I have just completed Chemo #5 of
Docetaxel
/Carboplatin combo. Now have lower back pain (like muscle spasm) on right side. Med Onc says that since my abdomen has retained fluid during this treatment (and I have had to upsize pants), pain probably due to stress on back due to extra load in front!
I have just completed Chemo #5 of
Docetaxel
/Carboplatin combo. Now have lower back pain (like muscle spasm) on right side. Med Onc says that since my abdomen has retained fluid during this treatment (and I have had to upsize pants), pain probably due to stress on back due to extra load in front!
vandy69
in
Advanced Prostate Cancer
6 years ago
"Researchers Develop New Strategy to Target Breast Cancer Metastasis in Bones"
Given they are using the same chemo commonly used in 1st line treatment for Stage 4 prostate cancer, what is the difference, if any, using this same chemo in nanoparticles, as discussed in the article below: "....researchers developed a nanoparticle containing the chemotherapy Taxotere (
docetaxel
)
Given they are using the same chemo commonly used in 1st line treatment for Stage 4 prostate cancer, what is the difference, if any, using this same chemo in nanoparticles, as discussed in the article below: "....researchers developed a nanoparticle containing the chemotherapy Taxotere (
docetaxel
)
JLS1
in
Advanced Prostate Cancer
6 years ago
Enjoy Every Moment
Hi everyone. Hard to believe that Christmas is already over. Paul and I hope you had a wonderful time wherever you are in the world and whatever you have been doing over the Christmas. Paul and I were at home. We listened to great Christmas concerts in front of the Christmas tree, caught up with family
Hi everyone. Hard to believe that Christmas is already over. Paul and I hope you had a wonderful time wherever you are in the world and whatever you have been doing over the Christmas. Paul and I were at home. We listened to great Christmas concerts in front of the Christmas tree, caught up with family
MelaniePaul
in
Advanced Prostate Cancer
6 years ago
I'm Struggling
I have been through, cryo-ablation to the prostate twice, Zolodex implants every 3 months, chemo (
Docetaxel
3 weekly for 6 rounds). I have also tried various protocols of 'alternative therapies', I eat well (plant based), I try to look after myself with meditation, regular exercise etc.
I have been through, cryo-ablation to the prostate twice, Zolodex implants every 3 months, chemo (
Docetaxel
3 weekly for 6 rounds). I have also tried various protocols of 'alternative therapies', I eat well (plant based), I try to look after myself with meditation, regular exercise etc.
paulofaus
in
Advanced Prostate Cancer
6 years ago
Great Success with Carboplatin
Just received results from second liver MRI after 3 cycles of
Docetaxel
and Carboplatin chemo. MRI revealed the some of my 20+ liver lesions had disappeared and others had decreased in size by 50%! Let's hear it for Carboplatin!!
Just received results from second liver MRI after 3 cycles of
Docetaxel
and Carboplatin chemo. MRI revealed the some of my 20+ liver lesions had disappeared and others had decreased in size by 50%! Let's hear it for Carboplatin!!
vandy69
in
Advanced Prostate Cancer
7 years ago
awstouten basis info
Chemo 6x
docetaxel
volgt nu. Graag wil ik info en gerichte tips over middelen of behandelingen die afhankelijk zijn. Alvast bedankt voor jullie inzet !!! 😊
Chemo 6x
docetaxel
volgt nu. Graag wil ik info en gerichte tips over middelen of behandelingen die afhankelijk zijn. Alvast bedankt voor jullie inzet !!! 😊
awstouten
in
Advanced Prostate Cancer
7 years ago
Docetaxel Rechallenge?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998742/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998742/
Hidden
in
Advanced Prostate Cancer
7 years ago
my journey
Have had radiation, tried zolodex then 20 treatments
docetaxel
then 68 treatments cabazitaxel chemo ended 1yr ago.numerous viscious side effects. currently on elligard and denosumab feeling great, little tired on elligard.
Have had radiation, tried zolodex then 20 treatments
docetaxel
then 68 treatments cabazitaxel chemo ended 1yr ago.numerous viscious side effects. currently on elligard and denosumab feeling great, little tired on elligard.
Izab
in
Advanced Prostate Cancer
7 years ago
Nalakrats is Big on Gators and Here We Find Out A Rat Does Not Effect Efficacy of Docetaxel
https://www.ncbi.nlm.nih.gov/pubmed/29164346 Gus
https://www.ncbi.nlm.nih.gov/pubmed/29164346 Gus
gusgold
in
Advanced Prostate Cancer
7 years ago
No appetite after chemo
Husband had first chemo (
Docetaxel
) treatment on 12/5/17. He is also on Loupron , Casodex and Prednisone. Made it thru the Neulasta bone aches and the other side effects but he says food doesn't taste right. He is hungry.
Husband had first chemo (
Docetaxel
) treatment on 12/5/17. He is also on Loupron , Casodex and Prednisone. Made it thru the Neulasta bone aches and the other side effects but he says food doesn't taste right. He is hungry.
benninger
in
Advanced Prostate Cancer
6 years ago
Introduction
He had 6 sessions of chemo (
Docetaxel
), and also monthly firmagon injections. PSA dropped steadily but never below 2. He then went to India for 6 weeks of tomotherapy, followed by a week of cyberknife. He was then also started on casodex, and the last PSA test a week ago was 0.73.....
He had 6 sessions of chemo (
Docetaxel
), and also monthly firmagon injections. PSA dropped steadily but never below 2. He then went to India for 6 weeks of tomotherapy, followed by a week of cyberknife. He was then also started on casodex, and the last PSA test a week ago was 0.73.....
blueeyes74
in
Advanced Prostate Cancer
7 years ago
Abiraterone / Docetaxel
While the side effects may not be as severe, they can be longer lasting than those seen with
docetaxel
. Adverse effects include high blood pressure and diabetes.
Docetaxel
, on the other hand, which is administered intravenously, only needs to be given to patients every 3 weeks for 6 cycles.
While the side effects may not be as severe, they can be longer lasting than those seen with
docetaxel
. Adverse effects include high blood pressure and diabetes.
Docetaxel
, on the other hand, which is administered intravenously, only needs to be given to patients every 3 weeks for 6 cycles.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
News from ESMO 2017.
As of now, "for patients with M1 {metastatic} prostate cancer at diagnosis, we have two standards of care: LHRH analog and
docetaxel
, and LHRH analogs and abiraterone.
As of now, "for patients with M1 {metastatic} prostate cancer at diagnosis, we have two standards of care: LHRH analog and
docetaxel
, and LHRH analogs and abiraterone.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
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