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Docetaxel
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Dicyclomine will work with Docetaxel ?
Will this work ? https://www.genengnews.com/topics/cancer/ibs-drug-restores-chemotherapy-effectiveness-against-resistant-prostate-cancer/
Will this work ? https://www.genengnews.com/topics/cancer/ibs-drug-restores-chemotherapy-effectiveness-against-resistant-prostate-cancer/
Manilo
in
Advanced Prostate Cancer
3 months ago
Triplet and now Radiation?
Just completed 6 sessions of chemo with
Docetaxel
. Got call from RO yesterday and they want to do radiation now. Of course I trust my medical team but curious of HU opinions on this path.
Just completed 6 sessions of chemo with
Docetaxel
. Got call from RO yesterday and they want to do radiation now. Of course I trust my medical team but curious of HU opinions on this path.
Yzinger
in
Advanced Prostate Cancer
2 months ago
Adding Docetaxel to T3b?
I was just reading the STAMPEDE trial and it appears some docs are adding
Docetaxel
to SOC for Stage 3 patients w/o cancer in the lymph nodes. a) anyone out there using
Docetaxel
for Stage 3?
I was just reading the STAMPEDE trial and it appears some docs are adding
Docetaxel
to SOC for Stage 3 patients w/o cancer in the lymph nodes. a) anyone out there using
Docetaxel
for Stage 3?
Adendino
in
Advanced Prostate Cancer
5 months ago
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More data about ARASENS, applied to the european part of the study population
And the benefit is such that it confirms that even when you give
docetaxel
, an early introduction of the AR pathway inhibitor is critical for the survival of these patients."
And the benefit is such that it confirms that even when you give
docetaxel
, an early introduction of the AR pathway inhibitor is critical for the survival of these patients."
Maxone73
in
Advanced Prostate Cancer
13 days ago
No more enzalutamide: docetaxel next up
Also got a new lesion in my thoracic spine so in addition to
docetaxel
, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks. Some fear for a while about the meds not working and progression but feeling more confident about the treatment plan now thankfully.
Also got a new lesion in my thoracic spine so in addition to
docetaxel
, a single dose of radiotherapy. Hope that will all be underway within a couple of weeks. Some fear for a while about the meds not working and progression but feeling more confident about the treatment plan now thankfully.
FortyWinks
in
Advanced Prostate Cancer
2 months ago
Divergent second opinion
He doesn't think that
Docetaxel
is warranted right now unless the genomic test on the biopsy tissue shows high risk markers. He also recommends radiating the prostate plus SBRT to the pelvis mets and to keep chemo as an option for later if needed.
He doesn't think that
Docetaxel
is warranted right now unless the genomic test on the biopsy tissue shows high risk markers. He also recommends radiating the prostate plus SBRT to the pelvis mets and to keep chemo as an option for later if needed.
Cali3
in
Advanced Prostate Cancer
4 months ago
Wait or start docetaxel?
MO suggested DORA Clinical trial (everyone gets
docetaxel
, half get radium) but the head of a trial I was previously in at NIH feels that unless a CT or Tc99 scan supports the findings of the PSMA scan I can wait, as long as I have a scan every 3 months.
MO suggested DORA Clinical trial (everyone gets
docetaxel
, half get radium) but the head of a trial I was previously in at NIH feels that unless a CT or Tc99 scan supports the findings of the PSMA scan I can wait, as long as I have a scan every 3 months.
AllenMarco
in
Advanced Prostate Cancer
5 months ago
What next after Docetaxel...?
On 4/19/23 I was seen by the trial MO to confirm the previous recommendation of 10 sessions of of
Docetaxel
after the new liquid biopsy confirmed the first one with no mutations. Meanwhile, the PSA has risen to 115 before a kidney issue and to about 350 just before Chemo.
On 4/19/23 I was seen by the trial MO to confirm the previous recommendation of 10 sessions of of
Docetaxel
after the new liquid biopsy confirmed the first one with no mutations. Meanwhile, the PSA has risen to 115 before a kidney issue and to about 350 just before Chemo.
Ollie1948
in
Advanced Prostate Cancer
5 months ago
Following SOC here in BC Canada
Started with ADT and
Docetaxel
. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing and had to get targeted radiation to painful spots on ribs.
Started with ADT and
Docetaxel
. Was able to be castrate sensitive for 4.5 years. Tried to add Abiraterone and it failed after a couple of months. Had Radium 223 and it was okay but did nothing to the PSA. Cancer kept progressing and had to get targeted radiation to painful spots on ribs.
Islandboy2021
in
Advanced Prostate Cancer
9 days ago
rising PSA and 'light' advancement of mets in hip bones. Diagnosed stage 4 in March 2021.
George at Duke March of 2023 and he had my husband on a round of
docetaxel
. After that the many bone mets and some on lungs 'disappeared'. Now it looks like they are starting to grow back. The PSA is not yet doubling since a couple months ago, but it's on the rise. Dr.
George at Duke March of 2023 and he had my husband on a round of
docetaxel
. After that the many bone mets and some on lungs 'disappeared'. Now it looks like they are starting to grow back. The PSA is not yet doubling since a couple months ago, but it's on the rise. Dr.
Newdiag-NC
in
Advanced Prostate Cancer
7 days ago
Any proof that removing a tumor off prostate bed by radiation or surgery is better than just systemic therapy ?
gland, cT3b CN0 cM1b Gleason 8 and 9 *4+5=9 Stage 4 Grade 5 : ypT3a YPT3a 3 lytic lesions resolved to 1 mild avid lesion Biopsy 15 samples 4 adenocarcinoma 11 benign Low volume High grade Triplicate Therapy Firmagon @28 days, Zytiga with Prednisone Daily, Metformin 500mg Daily
Docetaxel
gland, cT3b CN0 cM1b Gleason 8 and 9 *4+5=9 Stage 4 Grade 5 : ypT3a YPT3a 3 lytic lesions resolved to 1 mild avid lesion Biopsy 15 samples 4 adenocarcinoma 11 benign Low volume High grade Triplicate Therapy Firmagon @28 days, Zytiga with Prednisone Daily, Metformin 500mg Daily
Docetaxel
Shorehousejam
in
Advanced Prostate Cancer
13 days ago
Chemo Failed
My dad finished
Docetaxel
in November. He went to oncologist today. His PSA went from 0.58 to 2.3. Things he tried: Lupron (on for years before failed) Zytiga (worked for 18 months) Orchidectomy Then the chemo. He is not a candidate for radiation because of a previous cancer.
My dad finished
Docetaxel
in November. He went to oncologist today. His PSA went from 0.58 to 2.3. Things he tried: Lupron (on for years before failed) Zytiga (worked for 18 months) Orchidectomy Then the chemo. He is not a candidate for radiation because of a previous cancer.
Jshaw916
in
Advanced Prostate Cancer
3 months ago
mHSPCa with undetectable PSA - chemo-only?
“adding
docetaxel
to SOC treatment in patients with prostate cancer who are in otherwise good health with a PSA level of less than 4 ng/mLand a Gleason score of 8 to 10was associated with a significant reduction in prostate cancer specific mortality” “By adding
docetaxel
to the SOC treatment, the
“adding
docetaxel
to SOC treatment in patients with prostate cancer who are in otherwise good health with a PSA level of less than 4 ng/mLand a Gleason score of 8 to 10was associated with a significant reduction in prostate cancer specific mortality” “By adding
docetaxel
to the SOC treatment, the
Purple-Bike
in
Advanced Prostate Cancer
3 months ago
Docetaxel - how many rounds did you have?
Our oncologist has had people on
Docetaxel
for a year and a half. I'm wondering how long we might expect this treatment to be doable. Thanks, guys and gals - I read these posts daily and pray for you often.
Our oncologist has had people on
Docetaxel
for a year and a half. I'm wondering how long we might expect this treatment to be doable. Thanks, guys and gals - I read these posts daily and pray for you often.
Tinuriel
in
Advanced Prostate Cancer
1 month ago
Question, each month with rising PSA, when do I do a pet scan
Medical Oncologist suggested waiting for the next two months to see if it’s still rising… Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved Started Firmagon 7/6/2022 Zytiga with Prednisone 7/20/2022 currently still on these meds
Docetaxel
Chemotherapy on 08/11/2022
Medical Oncologist suggested waiting for the next two months to see if it’s still rising… Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved Started Firmagon 7/6/2022 Zytiga with Prednisone 7/20/2022 currently still on these meds
Docetaxel
Chemotherapy on 08/11/2022
Shorehousejam
in
Advanced Prostate Cancer
4 months ago
CONTACT-02 Phase III: Cabozantinib-Atezolizumab combination works well in mCRPC with soft tissue metastasis
with liver metastasis, offer a beacon of hope for a patient population with limited treatment options. " "There was a 57% reduction in risk of progression or death in patients with liver metastasis with cabo/atezo, [and] a 43% reduction in risk of progression or death in patients who received prior
docetaxel
with liver metastasis, offer a beacon of hope for a patient population with limited treatment options. " "There was a 57% reduction in risk of progression or death in patients with liver metastasis with cabo/atezo, [and] a 43% reduction in risk of progression or death in patients who received prior
docetaxel
Maxone73
in
Advanced Prostate Cancer
2 months ago
Docetaxel not working so stopped
I promised I would update you after my scan to see how the chemo was progressing. Well, the main reason for the chemo was that spots had appeared in my liver. Last week's CT scan showed that the spots have grown "significantly" so the chemo is not working. Also, my liver function blood test results -
I promised I would update you after my scan to see how the chemo was progressing. Well, the main reason for the chemo was that spots had appeared in my liver. Last week's CT scan showed that the spots have grown "significantly" so the chemo is not working. Also, my liver function blood test results -
Benkaymel
in
Advanced Prostate Cancer
4 months ago
PSMA-Addition Trial can give access to Pluvicto for DeNovo or mHSPC
The PSMA-Fore trial recently showed that it iis very beneficial before
docetaxel
chemotherapy in mCRPC. Now a worldwide trial is exploring it in metastatic hormone sensitive PC, including de novo metastatic.
The PSMA-Fore trial recently showed that it iis very beneficial before
docetaxel
chemotherapy in mCRPC. Now a worldwide trial is exploring it in metastatic hormone sensitive PC, including de novo metastatic.
MateoBeach
in
Advanced Prostate Cancer
3 months ago
Testosterone and adrenal glands
Hello all, so I finished 10 rounds of chemo
docetaxel
last year in September. My PSA was down to 2.8 Oct 5th. I had an orchiectomy Oct 15. My PSA started to rise. Nov 5th PSA 5.15. Dec 6th PSA 7.85.
Hello all, so I finished 10 rounds of chemo
docetaxel
last year in September. My PSA was down to 2.8 Oct 5th. I had an orchiectomy Oct 15. My PSA started to rise. Nov 5th PSA 5.15. Dec 6th PSA 7.85.
Eugmn
in
Advanced Prostate Cancer
3 months ago
New therapy (I hope I am not repeating myself)
https://www.urologytimes.com/view/antibody-drug-conjugate-plus-
docetaxel
-shows-promise-in-metastatic-prostate-cancer The novel antibody-drug conjugate PDS0301 (M9241) in combination with
docetaxel
demonstrated promising safety and immune response signals in patients with metastatic castration-sensitive
https://www.urologytimes.com/view/antibody-drug-conjugate-plus-
docetaxel
-shows-promise-in-metastatic-prostate-cancer The novel antibody-drug conjugate PDS0301 (M9241) in combination with
docetaxel
demonstrated promising safety and immune response signals in patients with metastatic castration-sensitive
Maxone73
in
Advanced Prostate Cancer
7 months ago
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