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dilemma ADT duration
apologies first for another longish verbose posting ! I am in a dilemma after my last oncology appointment - I have T2cN0M0 G9 locally contained PCa following a failed HIFU that was previously twice biopsied as G7. After a clear PSMA showing locally contained with no SV involvement I had 20x3Gy to
apologies first for another longish verbose posting ! I am in a dilemma after my last oncology appointment - I have T2cN0M0 G9 locally contained PCa following a failed HIFU that was previously twice biopsied as G7. After a clear PSMA showing locally contained with no SV involvement I had 20x3Gy to
SimMartin
in
Advanced Prostate Cancer
1 year ago
Was Chemo "Successful"?
I just had my first PSA test after waiting to allow the results to mean something, after 10 rounds of doxytaxel. I was supposed to wait three months but for convenience pushed it by a week. I was hoping for a close to 0 PSA but that is not the case. I see my oncologist in a little more than a week
I just had my first PSA test after waiting to allow the results to mean something, after 10 rounds of doxytaxel. I was supposed to wait three months but for convenience pushed it by a week. I was hoping for a close to 0 PSA but that is not the case. I see my oncologist in a little more than a week
spencoid2
in
Advanced Prostate Cancer
1 year ago
Change in Carcinoma
I had low dose brachytherapy in 2010 with seeds and success. My PSA started raising again in 2021. I opted for high dose brachytherapy and my PSA is 0.1. This year I had difficulty urinating and recently had a procedure similar to a TURP to remove tissue in my urethra near my prostate. This procedure
I had low dose brachytherapy in 2010 with seeds and success. My PSA started raising again in 2021. I opted for high dose brachytherapy and my PSA is 0.1. This year I had difficulty urinating and recently had a procedure similar to a TURP to remove tissue in my urethra near my prostate. This procedure
gegan01
in
Prostate Cancer Network
1 year ago
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Never get tired of annoucing I am STILL undetectable
108 bottles of Zytiga on the shelf. Got my latest PSA and blood test results. Once again, officially 8 years 9 months since November 2014 results, PSA still undetectable at <.008. Another Zero candy bar for me. (I bought a few, and been handing them out like cigars after a new birth.) I have had somewhat
108 bottles of Zytiga on the shelf. Got my latest PSA and blood test results. Once again, officially 8 years 9 months since November 2014 results, PSA still undetectable at <.008. Another Zero candy bar for me. (I bought a few, and been handing them out like cigars after a new birth.) I have had somewhat
Wings-of-Eagles
in
Advanced Prostate Cancer
1 year ago
Casodex query
About to go back on ADT this month because my PSA is doubling every 4 months My Nader was 0.02 in April 2021 but recent bloods are showing 2:6 and I’m expecting 5 plus on bloods done yesterday I was told in March this year that I had incurable cancer after a clear PSMA scan on the previous February .
About to go back on ADT this month because my PSA is doubling every 4 months My Nader was 0.02 in April 2021 but recent bloods are showing 2:6 and I’m expecting 5 plus on bloods done yesterday I was told in March this year that I had incurable cancer after a clear PSMA scan on the previous February .
Walliam
in
Advanced Prostate Cancer
1 year ago
Radiation for Salvage Treatment
I am about to start salvage treatment after a failed surgery and a rising PSA value of 0.1. However, I would like to know if weeks of external radiation with ADT, is the best treatment option here. The idea of blindly radiating pelvic area with a re-recurrence a few years later does not appeal to me.
I am about to start salvage treatment after a failed surgery and a rising PSA value of 0.1. However, I would like to know if weeks of external radiation with ADT, is the best treatment option here. The idea of blindly radiating pelvic area with a re-recurrence a few years later does not appeal to me.
Rams91
in
Prostate Cancer Network
1 year ago
LU-177 I&T, FAILURE?
Just received PSA results from 4th Infusion of LU-177 I&T, as part of the Eclipse Study. It increased from 0.1 to 0.2. PSA baseline was 2.0. Following 1st infusion PSA dropped to 0.3. Following 2nd infusion no PSA was taken. Following 3rd infusion PSA 0.1. Following 4th infusion PSA 0.2. Having
Just received PSA results from 4th Infusion of LU-177 I&T, as part of the Eclipse Study. It increased from 0.1 to 0.2. PSA baseline was 2.0. Following 1st infusion PSA dropped to 0.3. Following 2nd infusion no PSA was taken. Following 3rd infusion PSA 0.1. Following 4th infusion PSA 0.2. Having
john4803
in
Advanced Prostate Cancer
1 year ago
Update on my father
I just wanted to post a quick update on my father. He has metastatic castrate resistant prostate cancer. He’s been on ADT - Eligard shots every 3 months and prednisone + zytiga everyday. It’s challenging as I work with him and see all the ins and outs of his behaviour while on those meds. He remains
I just wanted to post a quick update on my father. He has metastatic castrate resistant prostate cancer. He’s been on ADT - Eligard shots every 3 months and prednisone + zytiga everyday. It’s challenging as I work with him and see all the ins and outs of his behaviour while on those meds. He remains
jberg22
in
Advanced Prostate Cancer
1 year ago
PSA rising
Just got this report from PSMA scan. Increased size of a few mildly tracer avid aorto-caval lymphnodes. The largest of these nodes measures 0.5 cm in short axis (image 204), previously measured 0.2 cm. Meet with MO tomorrow. I am 10 years in. Prostatectomy, bed radiation, and two years ago, whole
Just got this report from PSMA scan. Increased size of a few mildly tracer avid aorto-caval lymphnodes. The largest of these nodes measures 0.5 cm in short axis (image 204), previously measured 0.2 cm. Meet with MO tomorrow. I am 10 years in. Prostatectomy, bed radiation, and two years ago, whole
Jvaughan0
in
Advanced Prostate Cancer
1 year ago
Appreciate feedback on my going forward plan & timing
After 3 years from robotic RP with a 5+4 Gleason score, my PSA moved from zero to .099 ng/mL. See my profile for more data.
August
– Meetings with expert Dr. Collins (Georgetown). Wants to move fast with 5 days for 5 weeks radiation with six months of ADT (Orgovyx) due to my high Gleason from
After 3 years from robotic RP with a 5+4 Gleason score, my PSA moved from zero to .099 ng/mL. See my profile for more data.
August
– Meetings with expert Dr. Collins (Georgetown). Wants to move fast with 5 days for 5 weeks radiation with six months of ADT (Orgovyx) due to my high Gleason from
Murk
in
Prostate Cancer Network
1 year ago
Revisiting Intermittent Therapy in Metastatic Prostate Cancer
The A-Dream Phase 2 trial is taking a second look at intermittent therapy for mHSPCa. In the study they hope to answer the question 1. Can intermittent therapy (a break from treatment) for high responders (PSA < .2 over 18-24 mos) on ADT+ARPi be more effective than continuous ADT (the current standard
The A-Dream Phase 2 trial is taking a second look at intermittent therapy for mHSPCa. In the study they hope to answer the question 1. Can intermittent therapy (a break from treatment) for high responders (PSA < .2 over 18-24 mos) on ADT+ARPi be more effective than continuous ADT (the current standard
skiingfiend
in
Advanced Prostate Cancer
1 year ago
Pet scan vs CT scan
Hi fellow warriors, I've just had a phone appointment with my Oncologist my PSA is 0.7 and started to go up but not high enough to warrant having a Scan at the moment.My problem is she doesn't think she will be able to put me forward for a Pet scan as I have already had a couple in the past and with
Hi fellow warriors, I've just had a phone appointment with my Oncologist my PSA is 0.7 and started to go up but not high enough to warrant having a Scan at the moment.My problem is she doesn't think she will be able to put me forward for a Pet scan as I have already had a couple in the past and with
Chubby42
in
Advanced Prostate Cancer
1 year ago
excuse me asking. Brain fog.
Just a quickie, and excuse me for treading over old ground. Re starting Tapering , from 10 . My Dr called me whilst I was away, for an update on my Cancer Op, how was I feeling etc……. Mentioned to him about going back onto Pred, due to my fingers & hands . Long story short, wanted me to try and taper
Just a quickie, and excuse me for treading over old ground. Re starting Tapering , from 10 . My Dr called me whilst I was away, for an update on my Cancer Op, how was I feeling etc……. Mentioned to him about going back onto Pred, due to my fingers & hands . Long story short, wanted me to try and taper
Stifffingers
in
PMRGCAuk
1 year ago
taxotere and PSA
adt stopped 9/22, daralutamide mono therapy until 7/23. Three rounds of docetaxel until 7/17/23. PSA rose from 4.9 to 5.1. PSMA scan showed decline in bone Mets. Tried a bit of fasting. Just switched to cabitaxel due to seeming failure of docetaxel based on PSA rise. Wondering if PSA increase was the
adt stopped 9/22, daralutamide mono therapy until 7/23. Three rounds of docetaxel until 7/17/23. PSA rose from 4.9 to 5.1. PSMA scan showed decline in bone Mets. Tried a bit of fasting. Just switched to cabitaxel due to seeming failure of docetaxel based on PSA rise. Wondering if PSA increase was the
CWT53
in
Advanced Prostate Cancer
1 year ago
Indomethacin - resenisitize to Enza
In a preclinical study indo seems to resensitize to Enza by blocking CRXR7 thus indirectly AR-V7. The trial was started in 2018, results should be known in July 2023. Does anybody know anything from that trial? I just rechallenged with Enza bringing PSA down from 7 to 0.5, if adding cheap indo prevents
In a preclinical study indo seems to resensitize to Enza by blocking CRXR7 thus indirectly AR-V7. The trial was started in 2018, results should be known in July 2023. Does anybody know anything from that trial? I just rechallenged with Enza bringing PSA down from 7 to 0.5, if adding cheap indo prevents
Hidden
in
Fight Prostate Cancer
1 year ago
Surviving in retirement
At age 52 I was diagnosed with stage 3 Multiple Myeloma ; after 2 bone marrow transplants in 2007 & 2009 I was able to continue my engineering job until age 65. At 66 my PSA was 3400 with Gleason score 4 ; started Docetaxel and Jevtana until July 23 ; Now on Pluvicto have 5 more treatments to
At age 52 I was diagnosed with stage 3 Multiple Myeloma ; after 2 bone marrow transplants in 2007 & 2009 I was able to continue my engineering job until age 65. At 66 my PSA was 3400 with Gleason score 4 ; started Docetaxel and Jevtana until July 23 ; Now on Pluvicto have 5 more treatments to
chipspesto
in
Advanced Prostate Cancer
1 year ago
Simple Prostatectomy
Hello everyone , My father was diagnosed with locally advanced prostate cancer in March of 2021, PSA 6900 … After 3 months on Eligard his PSA dropped to 0.6 and it has been so for more than 2 years now. He has been on foley catheter since March of 2021 because of a very enlarged prostate and has refused
Hello everyone , My father was diagnosed with locally advanced prostate cancer in March of 2021, PSA 6900 … After 3 months on Eligard his PSA dropped to 0.6 and it has been so for more than 2 years now. He has been on foley catheter since March of 2021 because of a very enlarged prostate and has refused
naples2021
in
Advanced Prostate Cancer
1 year ago
ADT duration
I have locally contained G9 discovered July as PSA in June 2022 rose to 6.9 , 6 months after HIFU In December 2021. Immediately started Bicalutimide 150 3rd August 2022 and planned radiotherapy for end of November 2022 after clear PSMA. For various reasons I was on bicalutimide for longer than
I have locally contained G9 discovered July as PSA in June 2022 rose to 6.9 , 6 months after HIFU In December 2021. Immediately started Bicalutimide 150 3rd August 2022 and planned radiotherapy for end of November 2022 after clear PSMA. For various reasons I was on bicalutimide for longer than
SimMartin
in
Advanced Prostate Cancer
1 year ago
Long survivors with ADT + Xtandi (Enzulatamide)
5 years after RPE and RT my PSA is rising again. I am advised to start ADT + Xtandi. Who are longest still on this combination without getting castration resistant?
5 years after RPE and RT my PSA is rising again. I am advised to start ADT + Xtandi. Who are longest still on this combination without getting castration resistant?
ElemanJ
in
Advanced Prostate Cancer
1 year ago
Is Xtandi Failing?
Background: Diagnosis in Jan/2020, PSA 577, Gleason 9, mets to lymph nodes and bones Started Firmagon immediately as well as chemo, 6 cycles of Docetaxel. Followed this by radiation to the prostate. PSA dropped pretty quick and eventually into the teens and single digits, lowest was 4.5 back in January
Background: Diagnosis in Jan/2020, PSA 577, Gleason 9, mets to lymph nodes and bones Started Firmagon immediately as well as chemo, 6 cycles of Docetaxel. Followed this by radiation to the prostate. PSA dropped pretty quick and eventually into the teens and single digits, lowest was 4.5 back in January
GTTown
in
Advanced Prostate Cancer
1 year ago
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