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BP with abiraterone + prednisone, eplerenone, dexamethasone
I have been on Lupron and abiraterone with (initially) prednisone for 4.5 years, which has maintained my PSA at <0.1 since 111 at diagnosis. I have all the usual side effects. One that doesn't bother me day-to-day, but definitely concerns me, is hypertension. Before PCa, I had moderately high BP, which
I have been on Lupron and abiraterone with (initially) prednisone for 4.5 years, which has maintained my PSA at <0.1 since 111 at diagnosis. I have all the usual side effects. One that doesn't bother me day-to-day, but definitely concerns me, is hypertension. Before PCa, I had moderately high BP, which
Gearhead
in
Advanced Prostate Cancer
1 year ago
Declining psa #5
Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries š and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to
Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries š and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to
Nfler
in
Advanced Prostate Cancer
1 year ago
ADT before Surgery?
I have a prostatectomy which is probably 6-8 weeks in my future. My outlook is that metastasis in imminent. (T3bM0n0 and no evidence of cancer outside the gland as of May 25 PSMA PET scan, but I am told I am intermediate/unfavorable and my PSA went from 10 to 12 in only a month.) Today is August 18.
I have a prostatectomy which is probably 6-8 weeks in my future. My outlook is that metastasis in imminent. (T3bM0n0 and no evidence of cancer outside the gland as of May 25 PSMA PET scan, but I am told I am intermediate/unfavorable and my PSA went from 10 to 12 in only a month.) Today is August 18.
Lost_Sheep
in
Prostate Cancer Network
1 year ago
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Blood in urine and clotting 3 weeks after starting Zytiga
After starting Zytiga I noticed a few drops of blood but only after a bowel motion. Yesterday after a big bowel motion I couldnāt pee and headed for hospital though on getting there I suppose my bladder was full enough it forced the clot out while going to the toilet. Iāve had blockage problems ana
After starting Zytiga I noticed a few drops of blood but only after a bowel motion. Yesterday after a big bowel motion I couldnāt pee and headed for hospital though on getting there I suppose my bladder was full enough it forced the clot out while going to the toilet. Iāve had blockage problems ana
Ausi
in
Advanced Prostate Cancer
1 year ago
FYI: New data on progression of visceral mets without PSA progression (discordance) and ARAT/docetaxel therapy
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
SeosamhM
in
Advanced Prostate Cancer
1 year ago
Newly detectable PSA after prostatectomy: RT + ADT planned; add Erleada?
Diagnosed 12/21, PSA 7, negative PSMA PET. Radical prostatectomy with extended lymph node dissection in Mar 2022. Gleason 4+5, +cribriform, +intraductal, + bilat SVI, +ECE. Margins negative (barely) and 1/34 lymph nodes positive with very small focus of cancer. PSA was undetectable until Jun 2023, then
Diagnosed 12/21, PSA 7, negative PSMA PET. Radical prostatectomy with extended lymph node dissection in Mar 2022. Gleason 4+5, +cribriform, +intraductal, + bilat SVI, +ECE. Margins negative (barely) and 1/34 lymph nodes positive with very small focus of cancer. PSA was undetectable until Jun 2023, then
Brokedown_Palace
in
Advanced Prostate Cancer
1 year ago
Brain metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
pca2004
in
Fight Prostate Cancer
1 year ago
AUA 2023: PSA Response and Time-to-Castration Resistance Among Patients with mCSPCa Initiated on Apalutamide, Enzalutamide, or Abiraterone
The objective of this study was to describe a āreal-worldā experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
The objective of this study was to describe a āreal-worldā experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
skiingfiend
in
Advanced Prostate Cancer
1 year ago
Bring PSA from 6.7 to 3.1 in 4 weeks by pure water fast (3wks) and vegan diet (1 wk).
Note from moderator: NO ONE SHOULD ATTEMPT THE SUGGESTIONS IN THIS POST WITHOUT FIRST CONSULTING WITH YOUR UROLOGIST AND/or ONCOLOGIST. READ ALL OF THE COMMENTS BELOW THE POST. THE WISDOM AND CONCERN OF OUR COMMUNITY IS THE ONLY REASON THIS POST REMAINS PUBLISHED, I have prostate cancer, and I
Note from moderator: NO ONE SHOULD ATTEMPT THE SUGGESTIONS IN THIS POST WITHOUT FIRST CONSULTING WITH YOUR UROLOGIST AND/or ONCOLOGIST. READ ALL OF THE COMMENTS BELOW THE POST. THE WISDOM AND CONCERN OF OUR COMMUNITY IS THE ONLY REASON THIS POST REMAINS PUBLISHED, I have prostate cancer, and I
DADICIDAD
in
Advanced Prostate Cancer
1 year ago
Abiraterone and food
My husband has been on Abiraterone for 2 months, during which time his PSA has doubled. Iāve recently read posts about the advantages of taking Abiraterone with food instead of taking it an hour before eating as recommended. The posts are quite old (5 years) - is taking Abi with food still a consideration
My husband has been on Abiraterone for 2 months, during which time his PSA has doubled. Iāve recently read posts about the advantages of taking Abiraterone with food instead of taking it an hour before eating as recommended. The posts are quite old (5 years) - is taking Abi with food still a consideration
NLondon43
in
Advanced Prostate Cancer
1 year ago
Positive results, Pluvicto
Iām at Mayo for my third Pluvicto (Lutetium-177) treatment. Yesterday, I had a PSMA Pet scan to check on progress. Iām happy to report that itās all positive at this point in the game. I include below the āfindingsā on the radiology report from the scan which speaks for itself. I look forward to hearing
Iām at Mayo for my third Pluvicto (Lutetium-177) treatment. Yesterday, I had a PSMA Pet scan to check on progress. Iām happy to report that itās all positive at this point in the game. I include below the āfindingsā on the radiology report from the scan which speaks for itself. I look forward to hearing
Skifanatic
in
Advanced Prostate Cancer
1 year ago
PSA Bounce after radiation
Has anyone experienced a PSA rise after SBRT for bone metastasis? If so, would like to hear your story. Thanks.
Has anyone experienced a PSA rise after SBRT for bone metastasis? If so, would like to hear your story. Thanks.
NDJIM
in
Advanced Prostate Cancer
1 year ago
Rapidly Rising PSA
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
CrocodileShoes
in
Advanced Prostate Cancer
1 year ago
PSA drop after ADT
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
John347
in
Advanced Prostate Cancer
1 year ago
And on it goesā¦..
My Joe had his first ambulance ride yesterday. Despite all our communication with the anesthesiologist prior to a minor elbow surgery, he was laid flat on his back for the procedure. When he ācrashedā as the surgery ended, they sat him up, gave him two breathing treatments and decided to transport him
My Joe had his first ambulance ride yesterday. Despite all our communication with the anesthesiologist prior to a minor elbow surgery, he was laid flat on his back for the procedure. When he ācrashedā as the surgery ended, they sat him up, gave him two breathing treatments and decided to transport him
Cateydid
in
Advanced Prostate Cancer
1 year ago
PSA went from 0.97 to 0.99 during chemo treatments. Should we be concerned?
Hi all, My dad is currently going through chemo. History of his diagnosis is in my bio. He was diagnosed with stage 4 metastatic prostate cancer in March this year. We started triple therapy and just finished 4th dose of chemo. His latest blood results showed PSA of 0.99 however the ones 3 weeks before
Hi all, My dad is currently going through chemo. History of his diagnosis is in my bio. He was diagnosed with stage 4 metastatic prostate cancer in March this year. We started triple therapy and just finished 4th dose of chemo. His latest blood results showed PSA of 0.99 however the ones 3 weeks before
Jdhanoa
in
Advanced Prostate Cancer
1 year ago
ED No More (the prequel)
I've had so many comments since my post "ED no more" that I felt I should offer more. I'm a neophyte on this site. As a matter of fact I avoid this site. I have always adopted an "ignorance is bliss" attitude towards life and my PC. My wife, on the other hand, is a nervous but adventurous individual
I've had so many comments since my post "ED no more" that I felt I should offer more. I'm a neophyte on this site. As a matter of fact I avoid this site. I have always adopted an "ignorance is bliss" attitude towards life and my PC. My wife, on the other hand, is a nervous but adventurous individual
Bangkok
in
Advanced Prostate Cancer
1 year ago
puzzled with Orgovyx
First of all my score was 7(3+4) 6.5 to 7 years ago. I was taking nutrients and vitamins to fight the cancer which was working great until I had kidney stone surgery. Psa shot up to 101 which is when I stopped my self medication and then started the casadex which then brought my PSA down to 3. I was
First of all my score was 7(3+4) 6.5 to 7 years ago. I was taking nutrients and vitamins to fight the cancer which was working great until I had kidney stone surgery. Psa shot up to 101 which is when I stopped my self medication and then started the casadex which then brought my PSA down to 3. I was
woppaginny
in
Advanced Prostate Cancer
1 year ago
Thoughts on next steps
Hi all Iād appreciate thoughts/ input At 13 months of undetectable PSA from a multiple bone mets situation via 7 months of multi treatments I asked for a PSMA PET scan prior to considering an ADT holiday ( moving to Apalutamide as a monotherapy) I see my London onco on Monday but report in today has
Hi all Iād appreciate thoughts/ input At 13 months of undetectable PSA from a multiple bone mets situation via 7 months of multi treatments I asked for a PSMA PET scan prior to considering an ADT holiday ( moving to Apalutamide as a monotherapy) I see my London onco on Monday but report in today has
Brysonal
in
Fight Prostate Cancer
1 year ago
Changing from Amiodarone to Digoxin
I have recently been diagnosed with peripheral neuropathy in my lower legs and feet. I have AF and have diabetes II. I have been told that the treatment for my peripheral neuropathy is not suitable when taking Amiodarone so the pharmacist has suggested that I change to Digoxin. Has anyone done this or
I have recently been diagnosed with peripheral neuropathy in my lower legs and feet. I have AF and have diabetes II. I have been told that the treatment for my peripheral neuropathy is not suitable when taking Amiodarone so the pharmacist has suggested that I change to Digoxin. Has anyone done this or
Christabelle27
in
British Heart Foundation
2 years ago
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