PSA Bounce after radiation

[NDJIM]

Has anyone experienced a PSA rise after SBRT for bone metastasis? If so, would like to hear your story. Thanks.

[Tall_Allen]

It almost always occurs.

[NDJIM in reply to Tall_Allen]

Thank you as always, Tall Allen. I’m about 4 weeks out….just worried. Again, thanks so much. Jim

[Steel67 in reply to NDJIM]

Im 5 weeks out from SBRT to spine and hip- PSA went .057 to .075, ALP went 84 to 94….I’ll keep checking

[PCaWarrior]

I asked my Mayo RO. He said that it will not happen to me since I am doing SBRT. According to him it only happens if you radiate a prostate (stimulation).

[MoonRocket in reply to PCaWarrior]

What area are you getting sbrt too?

[PCaWarrior in reply to MoonRocket]

Two lymph nodes. Pelvic and a paraaortic.

I had an RP in 2018 and according to my Mayo RO I won't have a PSA bounce.

[MoonRocket in reply to PCaWarrior]

Got it...I guess they showed up on a PSMA scan. Good luck.

[PCaWarrior in reply to MoonRocket]

Thanks. Stable per RECIST. Do you know if they take timeframes into account?

In my case, tumors were around 0.5 cm in the summer. Now they are about 0.6 cm. 3 months, 20%.

[MoonRocket]

I had a small bounce when I had IMRT .1 to be exact. You'll need to give it some time to calm down after your treatments.