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Mice ‘cured’ of Parkinson’s in accidental scientific discovery
Not sure if this has been posted before - https://www.yahoo.com/lifestyle/parkinsons-disease-cure-treatment-tremor-093219804.html Mice were “cured” of Parkinson’s disease after a scientific study took an unexpected turn. Scientists from the University of California (UC) in San Diego set out to better
Not sure if this has been posted before - https://www.yahoo.com/lifestyle/parkinsons-disease-cure-treatment-tremor-093219804.html Mice were “cured” of Parkinson’s disease after a scientific study took an unexpected turn. Scientists from the University of California (UC) in San Diego set out to better
John_morris71
in
Cure Parkinson's
4 years ago
So I finished the book...
I didn't know what to expect, maybe a primer on running and PD. Lots of aphorisms similar to Just Do It and Git 'er Done. Learned that standing is more difficult than running because it uses more dopamine. And Steve Evans was the first marathon finisher to have had DBS treatment. He finished
I didn't know what to expect, maybe a primer on running and PD. Lots of aphorisms similar to Just Do It and Git 'er Done. Learned that standing is more difficult than running because it uses more dopamine. And Steve Evans was the first marathon finisher to have had DBS treatment. He finished
kaypeeoh
in
Cure Parkinson's
4 years ago
Medicine/Supplement Regime (Mucuna etc)
I just thought I'd share my dad's current medicine regime in case it will help other people. After so many months of trial and error, we have finally found a dose that works for my dad. He takes it every 2 hours and 45 minutes with little freezing, has less dyskinesias, not much pain, a better appetite
I just thought I'd share my dad's current medicine regime in case it will help other people. After so many months of trial and error, we have finally found a dose that works for my dad. He takes it every 2 hours and 45 minutes with little freezing, has less dyskinesias, not much pain, a better appetite
pdkid
in
Cure Parkinson's
4 years ago
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Neupro patch
Hi, I am new to this site & have been following some of the posts over the last few weeks. I have noticed a lot of you mention how bad dopamine is. I am a 60 yr old women, very fit with walking & pilates every day. I have suffered from RLS for many years, the only thing that helped & assured a few hours
Hi, I am new to this site & have been following some of the posts over the last few weeks. I have noticed a lot of you mention how bad dopamine is. I am a 60 yr old women, very fit with walking & pilates every day. I have suffered from RLS for many years, the only thing that helped & assured a few hours
banjololapoppy
in
Restless Legs Syndrome
4 years ago
One-time treatment generates new neurons, eliminates Parkinson's disease in mice
A groundbreaking study lights up a new way of approaching PD treatment . " Researchers around the world have tried many ways to generate neurons in the lab, using stem cells and other means, so we can study them better, as well as to use them to replace lost neurons in neurodegenerative diseases," said
A groundbreaking study lights up a new way of approaching PD treatment . " Researchers around the world have tried many ways to generate neurons in the lab, using stem cells and other means, so we can study them better, as well as to use them to replace lost neurons in neurodegenerative diseases," said
Abdiqani
in
Cure Parkinson's
4 years ago
Mucuna Puriens or natural Dopamine and Grapefruit juice
Does anyone have experience is using the natural source of Dopamine ( Mucuna Puriens) ? A few questions pop to mind, how do you decide on the dose? How do you time taking it in relation to eating? Can you take it as a supplement to your other Parkinson's medications? What frequency do you take it ?
Does anyone have experience is using the natural source of Dopamine ( Mucuna Puriens) ? A few questions pop to mind, how do you decide on the dose? How do you time taking it in relation to eating? Can you take it as a supplement to your other Parkinson's medications? What frequency do you take it ?
ccr69
in
Cure Parkinson's
4 years ago
Anyone else with RLS & mind racing? Poor quality sleep.....
My RLS is under control with dopamine agents, insofar as the sensation in my legs is concerned...but my mind is constantly active and I don't sleep deeply at all. It's not consistent, sometimes it's worse than other times. I know the drugs can cause insomnia. I don't have a problem falling asleep, usually
My RLS is under control with dopamine agents, insofar as the sensation in my legs is concerned...but my mind is constantly active and I don't sleep deeply at all. It's not consistent, sometimes it's worse than other times. I know the drugs can cause insomnia. I don't have a problem falling asleep, usually
silkusmaximus
in
Restless Legs Syndrome
4 years ago
I am New here
Hi,I am drummer67, dx in august 2018, when as a drummer, I found I was losing the ability to do my Blues shuffle drum groove. I am finding the topics on PTT-FUS and autologous dopamine stem cell transplants as hopeful tx's for me in the future.I still work part time and do lots of bicycling and downhill
Hi,I am drummer67, dx in august 2018, when as a drummer, I found I was losing the ability to do my Blues shuffle drum groove. I am finding the topics on PTT-FUS and autologous dopamine stem cell transplants as hopeful tx's for me in the future.I still work part time and do lots of bicycling and downhill
Hidden
in
Cure Parkinson's
4 years ago
please help
i am a mommy to a 5yo daughter recently dx with severe combined adhd & odd.. possible sensory issues (among other things).. it was also recently explained that, due to complications at birth, her brain is not creating enough (if any) dopamine ("she needs meds").. due to a blood disorder, her hematologist
i am a mommy to a 5yo daughter recently dx with severe combined adhd & odd.. possible sensory issues (among other things).. it was also recently explained that, due to complications at birth, her brain is not creating enough (if any) dopamine ("she needs meds").. due to a blood disorder, her hematologist
pRoudmommy2014
in
CHADD's ADHD Parents Together
4 years ago
How dopamine drives brain activity | motor cortex, insular cortex. MIT News.
How dopamine drives brain activity | motor cortex, insular cortex. MIT News. MIT biological engineers have created a specialized sensor that allows them to track dopamine in the brain using magnetic resonance imaging (MRI), as shown in the bottom row. Images in the top row show overall brain activity
How dopamine drives brain activity | motor cortex, insular cortex. MIT News. MIT biological engineers have created a specialized sensor that allows them to track dopamine in the brain using magnetic resonance imaging (MRI), as shown in the bottom row. Images in the top row show overall brain activity
aspergerian
in
Cure Parkinson's
4 years ago
Study - sugar dampens dopamine
A lot of people find eating sugar increases RLS could this be a clue. High-sugar diet dampens release of dopamine, triggering overeating "On a high-sugar diet, we find that the fruit flies' dopaminergic neurons are less active, because the high sugar intake decreases the intensity of the sweetness signal
A lot of people find eating sugar increases RLS could this be a clue. High-sugar diet dampens release of dopamine, triggering overeating "On a high-sugar diet, we find that the fruit flies' dopaminergic neurons are less active, because the high sugar intake decreases the intensity of the sweetness signal
Goldy700
in
Restless Legs Syndrome
4 years ago
Alcohol is a main RLS trigger for me
After many experiments with excluding different things from my diet I have to admit that the main trigger is an alcohol. Say, what's wrong with only 1 drink, especially if it's a red wine? Or a little bit a good brandy to fall asleep faster? Yeah, I always knew that alcohol does mess with your sleep,
After many experiments with excluding different things from my diet I have to admit that the main trigger is an alcohol. Say, what's wrong with only 1 drink, especially if it's a red wine? Or a little bit a good brandy to fall asleep faster? Yeah, I always knew that alcohol does mess with your sleep,
Alex2308
in
Restless Legs Syndrome
4 years ago
Probiotics exacerbating restless legs
Hi, I've a history of RLS but have made big improvements. However, I just took a high dose probiotic (500 billion CFU per day for a week) and it's really triggered a return. I feel this surge of energy in my legs, and then they this involuntary movement. My best guess is that the probiotics settled in
Hi, I've a history of RLS but have made big improvements. However, I just took a high dose probiotic (500 billion CFU per day for a week) and it's really triggered a return. I feel this surge of energy in my legs, and then they this involuntary movement. My best guess is that the probiotics settled in
RoDomHarr
in
Restless Legs Syndrome
4 years ago
Why Dopamine Freezes Parkinson Patients And Drives Drug Addicts
A dopamine imbalance triggers Parkinson's disease and drug addition -- two opposite diseases. How it worked to do this in the brain had been a mystery. New research shows dopamine strengthens and weakens the two primary circuits in the brain that control our behavior. This provides new insight into why
A dopamine imbalance triggers Parkinson's disease and drug addition -- two opposite diseases. How it worked to do this in the brain had been a mystery. New research shows dopamine strengthens and weakens the two primary circuits in the brain that control our behavior. This provides new insight into why
Kia17
in
Cure Parkinson's
4 years ago
How is PD connected to Restless Leg Syndrome?
Or is it? I had a mild degree of RLS for several years. It wasn't enough of a problem to warrant medical help. Over the past few months the restless leg has gotten worse. Coincidentally two years I was diagnosed with PD. I was on Sinemet for over a year. Stopped it and switched to amantadine
Or is it? I had a mild degree of RLS for several years. It wasn't enough of a problem to warrant medical help. Over the past few months the restless leg has gotten worse. Coincidentally two years I was diagnosed with PD. I was on Sinemet for over a year. Stopped it and switched to amantadine
kaypeeoh
in
Cure Parkinson's
4 years ago
2 Compounds Show Ability to Protect Neurons, Raise Dopamine Levels
"Two compounds with hormone-like effects — prostaglandin E1 (PGE1) and prostaglandin A1 (PGA1) — may help to increase dopamine levels in the brain and slow Parkinson’s progression by activating a protein, called Nurr1, that supports dopaminergic neurons, a study reports." https://parkinsonsnewstoday.com
"Two compounds with hormone-like effects — prostaglandin E1 (PGE1) and prostaglandin A1 (PGA1) — may help to increase dopamine levels in the brain and slow Parkinson’s progression by activating a protein, called Nurr1, that supports dopaminergic neurons, a study reports." https://parkinsonsnewstoday.com
pvw2
in
Cure Parkinson's
4 years ago
Is there a limit on Dopaboost intake?
My dad is on a surgery waitlist for DBS here in Canada (probably next year) and we could potentially do FUS in Switzerland... But in the meantime, we have been trying to figure out the best dopamine sources to help him on the daily. Mucuna is much more effective than his Sinemet, which barely works anymore
My dad is on a surgery waitlist for DBS here in Canada (probably next year) and we could potentially do FUS in Switzerland... But in the meantime, we have been trying to figure out the best dopamine sources to help him on the daily. Mucuna is much more effective than his Sinemet, which barely works anymore
pdkid
in
Cure Parkinson's
4 years ago
Life without dopamine
Is a lot less funner than with. Everything seems so boring. Nothing exciting. Trying to hang in there and take my b1. And 10 other meds and supplements. Hard to get excited when your brain has to squeeze itself so hard just to get a tiny drop of the reward neurotransmitter. Sorry just another rant
Is a lot less funner than with. Everything seems so boring. Nothing exciting. Trying to hang in there and take my b1. And 10 other meds and supplements. Hard to get excited when your brain has to squeeze itself so hard just to get a tiny drop of the reward neurotransmitter. Sorry just another rant
bassofspades
in
Cure Parkinson's
4 years ago
Other reasons for arm tremor?
If Sinemet or other dopamine agonists have no effect on tremor does that suggest the root problem is not a dopamine deficiency?
If Sinemet or other dopamine agonists have no effect on tremor does that suggest the root problem is not a dopamine deficiency?
kaypeeoh
in
Cure Parkinson's
4 years ago
Breathing abnormalities in Parkinsons
Several different patterns of breathing abnormality may be found in PD: Upper airway obstruction (UAO) has been reported in a third of people with PD. The most common manifestation of UAO is soft speech, which itself may affect up to 70% of people with PD. Two types of UAO have been described: (i)
Several different patterns of breathing abnormality may be found in PD: Upper airway obstruction (UAO) has been reported in a third of people with PD. The most common manifestation of UAO is soft speech, which itself may affect up to 70% of people with PD. Two types of UAO have been described: (i)
Hidden
in
Cure Parkinson's
4 years ago
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