Experiences with

Dexamethasone Intensol

Strategies to Resensitize CRPC to AR-Targeted Therapies Castration-resistant prostate cancer (CRPC) often remains driven by the androgen receptor (AR) pathway despite resistance to standard AR-targeted treatments. Numerous strategies – from drugs and combinations to hormonal cycling and lifestyle changes

What is the equivalent of 10 mg Prednisone if it gets replaced with Dexamethasone. My Dad has been for 3.5 years on Abiraterone and Prednisone (10 mg daily). We are trying to see if replacing Prednisone with Dexamethasone would help, but the oncologist prescribed only 0.5 mg Dexamethasone. Is this enough

PSA up to 3.8 and scans show progression (in bones only). Currently continuing with Abi/pred and decapeptyl. Reading the systematic review of switch to dexamethasone suggests to me it's worth a try. MO is resisting, quoting possible side effects of edema, fatigue, hypertension etc (husband is

Thoughts? MateoBeachOpinion? I recall you were using curcumin and maybe some others? Drug/Therapy (Mechanism / Status) Sipuleucel-T (Autologous dendritic cell vaccine; approved) Pembrolizumab (PD-1 checkpoint inhibitor; approved for MSI-high) Ipilimumab (CTLA-4 checkpoint inhibitor; experimental

Few months ago, my Dad’s PSMA Pet showed small L2 and T8 Mets. We decided to do Provenge and after that SBRT to the Mets with Dr Kishan at UCLA. The MRI right before the radiation showed a lot more than the PSMA Pet did : “Significantly progressed multifocal marrow replacing vertebral lesions throughout

Hi, my name is Deb and I’m hoping to find some answers about proper medication for Burning Mouth Syndrome which would help to relieve the pain and discomfort. I am using a natural toothpaste, as suggested by my dental expert and I’ve dried Dexamethasone rinse which hasn’t really helped as well as a salve

Hi, as my updated bio explains, I have recently been diagnosed with a complication of multiple myeloma called AL Amyloidosis. This is rare (60 cases per annum in the UK) and is where amyloids (a consequence of the abnormal plasma cells underlying the multiple myeloma) clump together and attach to organs

I went transitional blind in 4/24. I was put on dexamethasone and had a temporal artery biopsy which was negative. I also had many immunity tests done. I also had irisitis with eye drops given in 2/24. I saw a rheumatologist in 5/24. I was diagnosed with GCA with a PMR overlap. I was started on Actemra

I have a history of low BP. I have been on meds for this off and on. Off for quite a while and then I switched to Dexa. My BP tanked. I finally called my specialist who helps me with my BP and I asked if switching had anything to do with the problem. He said yes. Pred has a couple components (can’t remember

I read that when zytiga and deltacortene fail, replacing deltacortene with dexamethasone allows zytiga to continue to be effective. I have been interested in prostate cancer for many years but I had never heard of this and I must admit that it surprised me a lot. Does anyone know how this is possible

Hello and Happy and Healthy New Year to all. My latest question: When should our MO be concerned about a rise in PSA? My husband was diagnosed as metastatic in Sept 2021. Many mets to lymph nodes and bones. ( PSA was 7000+) He still has his prostate so I understand getting to undetected PSA

hello Does anyone know if we need to use a PPI or H2 blocker alongside using steroids? Do you not? I take my 4Mg dex with my cereal which is bran flakes and milk..

I had a visit with Dr. Denmeade this afternoon. My interest was in two areas. Theses areas were BAT and gut micrombe’s effect on prostate cancer patients. He was incredibly attentive and was taking notes as I told him my 24 year story battling PCa. and offered no condemnation for postponing treatment

It seems I am turning CRPC. My PSA is still low at .42 but it has gone up 8 fold since January. I have been lucky to have stayed CSPC for six years. Time to think about the next steps. I talked to my MO yesterday. I am switching from prednisone to dexamethasone right away. Getting new scans in January

Hi, I had an eyelea injection on Monday. On monday and Tuesday it felt fine and I started working on my laptop etc as normal but then on Tuesday night, my eyes started to feel very painful and gritty. My mum said it looked very bulgy too I went to the hospital on Wednesday and the doctor said it looked

Hi All, I was recently taking Dexamethasone and have started a new medication called Belzutifan. I have stopped from Tuesday 19th November 2024. I had a Liver blood test done on Tuesday 19th November 2024 and normally I am in normal range for everything please see below my blood test results is

Here is the answer. I am currently on Prednisolone, so will ask if I can change to Dexamethasone. Efficacy Comparison Dexamethasone appears to be more effective than prednisolone in treating castration-resistant prostate cancer (CRPC): A randomized phase 2 trial compared daily dexamethasone (0.5

My husband was diagnosed with a GBM grade 4 in an inoperable position in March this year. He has had radiotherapy and chemo tablets. Also taking a low dose of dexamethasone. His medical team has been fantastic and we are carrying on as best we can. But he has a constant headache which he cannot shift

This is going to be a long story and I hope there is someone in this group who can offer advice. What treatment is used for skin problems? I have a sarcoidosis diagnosis (biopsy of lymph node in my 30s, now late 70s). Always had some kind of relatively minor skin problems most of my life. No one

Mr. Spouse 21 is starting a Docetaxel rechallenge next week--3 rounds then another PMSA-PET scan. If you did a Docetaxel rechallenge as well, can you compare your early experiences with the rechallenge in terms of side effects and effectiveness and where you are now? He developed neuropathy despite using