At what PSA will a PSMA PET scan be useful?

[Rodeoz15]

Hi everyone

My father has been on Lupron for 3 years now. We stopped Abi last year due to rising blood sugar levels. His PSA used to hover between 0.6-0.8 (with an occasional spike to 1.2). PSA in May 24 was 0.6. Today, however, his PSA came back as 2.5.

Plan is to restart Abi and monitor. But I wanted to check when should we get a PSMA? Will a PSMA now be useful, or should be wait to see if restarting Abi helps? And when should be the next blood work? Is 15 day okay? His PSA seems to have increased 4x in 3 months, although it had 2xed in the past as well before going down again.

Last PSMA was in May 23 which was normal (bone mets but normal SUV values).

He is not a candidate for chemo.

Thanks!

[addicted2cycling]

just what I found --

pylarify.com/pca-imaging

**According to PYLARIFY, their PET/CT scan can improve prostate cancer disease assessment even when PSA levels are low. In general, PSMA PET scans are effective at PSA levels above 0.2 ng/mL. The detection rate for PSA levels below 0.2 is very low, but it increases to about 40% between 0.2 and 0.5 ng/mL. For PSA levels between 2 and 5 ng/mL, the detection rate is around 90% or higher.**

[Tall_Allen]

0.5 or rising rapidly is necessary for detection. But it doesn't sound like he needs it - he should restart abi regardless.