bone Mets!

[Nubeqa22]

it’s here. After 11 1/2 years on zoladex injections and Xtandi followed by Nubeqa, husband had a PET scan that shows numerous spots on spine, breastbone and one lymph node in groin. PSA was undetectable for years, then .1 and .2, which triggered the order for the scan. The PA told him he has 1-2years, but the oncologist tells us it’s “not entirely bad news” and that depending on therapies, he might have more time than that. We have been together since we were high school seniors and I am beyond devastated. Looking for hope here.

Nubeqa 22

[Tall_Allen]

Has he had docetaxel yet?

[Nubeqa22 in reply to Tall_Allen]

No. Not familiar with it. Should something be started sooner than 2 months from now when next PEt will be scheduled?

[allie2020]

My opinion is that you can pretty much dismiss what the PA said. Your husband may very well live for many, many years with you by his side. Tall Allen is the expert here so pay close attention to anything he says. Here is a pretty basic article on chemotherapy from John Hopkins and it discusses doxcetaxel as well as other chemo. drugs.

hopkinsmedicine.org/health/...

[Nubeqa22 in reply to allie2020]

Thank you! You have given me hope.

[God_Loves_Me]

Listen to Tall_Allen and setup appointment with oncologist and also talk multiple of oncologist and understand the situations properly. Also setup appointment with Radiations oncologist as well

[103532]

I have talked to so many here that have lived for years with recurrent prostate cancer in the bones. First, has he had genetic (Germline) testing? For example, if he is BRAC1 or 2 positive, he may respond really well to a Parp Inhibitor. There are so many things that may be helpful. Sometimes Docetaxel can desensitize the cancer to the ADT and second generation ADT's like Zytiga, Xtandi, Erleada, etc... Also, there is Cabazitaxel chemotherapy if Docetaxel failed, Lutetium (like Pluvicto), and immunotherapies. Of course, if the mets can be safely spot radiated combined with one or more of these other treatment options, it may buy a lot of time. If a met could be biopsied for mutations, all the better. Please be proactive and do not give up hope. I have learned a lot from this forum when my husband became oligorecurrent in his abdominal lymph nodes. Please keep us posted!

[Nubeqa22 in reply to 103532]

Don’t think he had genetic testing. It’s been 11 years since this journey started.. His father died from PCA, so likely genetic. 🤷‍♀️ Thank you for your expertise. More info on why I need to have further conversations with his med team.