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My path to combination therapy
I was diagnosed with hypothyroidism about 25 years ago, in my mid-thirties. For almost 20 years, I took only Levothyroxine. I realise now that I was probably depressed for the whole period. Back in 2016, I decided to quit drinking alcohol. I wasn't an alcoholic, but I was drinking every day, and sometimes
I was diagnosed with hypothyroidism about 25 years ago, in my mid-thirties. For almost 20 years, I took only Levothyroxine. I realise now that I was probably depressed for the whole period. Back in 2016, I decided to quit drinking alcohol. I wasn't an alcoholic, but I was drinking every day, and sometimes
Morphiouso
in
Thyroid UK
2 months ago
Inflammatory Arthritis
Hello everyone, I was diagnosed with inflammatory arthritis this past October and the rheumatologist tried to put me on Methotroxate and I kindly declined after seeing all the negative reviews about it. I’m only 31 years old and have to get fluid drained off of my knee at least 1-2 times a year. Has
Hello everyone, I was diagnosed with inflammatory arthritis this past October and the rheumatologist tried to put me on Methotroxate and I kindly declined after seeing all the negative reviews about it. I’m only 31 years old and have to get fluid drained off of my knee at least 1-2 times a year. Has
rms3377
in
NRAS
2 months ago
New to the community
Hi there, I'm Weng , 57, from Singapore. Last year, I was told by my neurologist that I have PD. The news came when I was about to retire. My goal is stay off medication and continue living a normal life. I have made a lot of lifestyle change since that fateful day. Things I do to help myself: brisk
Hi there, I'm Weng , 57, from Singapore. Last year, I was told by my neurologist that I have PD. The news came when I was about to retire. My goal is stay off medication and continue living a normal life. I have made a lot of lifestyle change since that fateful day. Things I do to help myself: brisk
Weng888
in
Cure Parkinson's
2 months ago
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Side Effects of Herceptin and Perjeta
I had 1.5 cm local, node negative breast cancer recurrence 3.3 years after my first breast cancer diagnosis. HER2+ PR+ ER+( triple positive). I opted not to have Chemo, but did have targeted therapy for the HER2+ cancer, Herceptin and Perjeta subcutaneous injections for a year. The worst constant side
I had 1.5 cm local, node negative breast cancer recurrence 3.3 years after my first breast cancer diagnosis. HER2+ PR+ ER+( triple positive). I opted not to have Chemo, but did have targeted therapy for the HER2+ cancer, Herceptin and Perjeta subcutaneous injections for a year. The worst constant side
Hidden
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SHARE Breast Cancer Support
2 months ago
New drug approved in Europe for uncontrolled COPD.
Good news folks! I learnt today that there is a new drug out for uncontrolled COPD with evidence type 2 inflammation levels. This medication is called Dupixent and has been approved for use in Europe by the European Medicines Agency. Before you get too excited, of course this doesn't mean that
Good news folks! I learnt today that there is a new drug out for uncontrolled COPD with evidence type 2 inflammation levels. This medication is called Dupixent and has been approved for use in Europe by the European Medicines Agency. Before you get too excited, of course this doesn't mean that
PaulineHM
in
Lung Conditions Community Forum
2 months ago
New Drug on the near horizon.
Good news folks! I learnt today that there is a new drug out for uncontrolled COPD with evidence type 2 inflammation levels. This medication is called Dupixent and has been approved for use in Europe by the European Medicines Agency. Before you get too excited, of course this doesn't mean that it
Good news folks! I learnt today that there is a new drug out for uncontrolled COPD with evidence type 2 inflammation levels. This medication is called Dupixent and has been approved for use in Europe by the European Medicines Agency. Before you get too excited, of course this doesn't mean that it
PaulineHM
in
COPD Friends
2 months ago
New Clinical Trial Starting: A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD) (REGENERATE-PD)
Here is a link to the trial on clinicaltrials.gov https://clinicaltrials.gov/study/NCT06285643?term=REGENERATE-PD&rank=1 Below is an excerpt from a news article about the trial: A new Phase II trial, REGENERATE-PD, will study AB-1005, an adeno-associated virus 2 (AAV2) glial cell line-derived neurotrophic
Here is a link to the trial on clinicaltrials.gov https://clinicaltrials.gov/study/NCT06285643?term=REGENERATE-PD&rank=1 Below is an excerpt from a news article about the trial: A new Phase II trial, REGENERATE-PD, will study AB-1005, an adeno-associated virus 2 (AAV2) glial cell line-derived neurotrophic
Canddy
in
Cure Parkinson's
2 months ago
Update on FIL -Venetoclax as a Monotherapy, Pancytopenia and Myelodysplasia
Hi everyone I have been meaning to post an update for months but things have been changing so rapidly, every day would have been a different story. So we did get to see a specialist who did a BM biopsy and recommended Venetoclax as a Monotherapy as his BM was 50% CLL. We were told it wasn't chemo
Hi everyone I have been meaning to post an update for months but things have been changing so rapidly, every day would have been a different story. So we did get to see a specialist who did a BM biopsy and recommended Venetoclax as a Monotherapy as his BM was 50% CLL. We were told it wasn't chemo
JoeMcDote
in
CLL Support
2 months ago
Help!
Hello everyone. 💙It's been six months since my mother had herpes encephalitis type 1, but she still can't stand up and is physically weak. I don't know if occupational therapy is useful or not? What should I do to improve her physical condition?
Hello everyone. 💙It's been six months since my mother had herpes encephalitis type 1, but she still can't stand up and is physically weak. I don't know if occupational therapy is useful or not? What should I do to improve her physical condition?
Ftmz
in
Encephalitis International
2 months ago
Newly diagnosed with HCC
I am a 78 year old retired educator who has battled GIST CANCER for 20 years. To my surprise, An HCC tumor was found in my liver in between two GIST tumors. in my June 5 MRI. The GIST tumors were shrinking out of site thanks to be taking Gleevec, a targeted therapy drug. My surgeon could not safely resect
I am a 78 year old retired educator who has battled GIST CANCER for 20 years. To my surprise, An HCC tumor was found in my liver in between two GIST tumors. in my June 5 MRI. The GIST tumors were shrinking out of site thanks to be taking Gleevec, a targeted therapy drug. My surgeon could not safely resect
Dachshund45
in
Blue Faery Liver Cancer
2 months ago
Advice
Hi All, I have hearing loss in both ears and have tinnitus all the time. This is a difficult challenge for us all. The doctors just put you on betahistine or amitriptyline or alprazolam or any anti depressants they say it helps reduce tinnitus or improve blood flow to inner ear. This is the same
Hi All, I have hearing loss in both ears and have tinnitus all the time. This is a difficult challenge for us all. The doctors just put you on betahistine or amitriptyline or alprazolam or any anti depressants they say it helps reduce tinnitus or improve blood flow to inner ear. This is the same
CMRN11
in
Tinnitus UK
2 months ago
More about Cu-67 PSMA : it seems better than Pluvicto (Lutetium) and it looks like experts are pushing it toward first line treatment!
I have already talked about this but it continues to look promising, so here is an update: https://www.urotoday.com/video-lectures/asco-2024/video-2/mediaitem/4152-secure-trial-copper-67-psma-therapy-for-prostate-cancer-geoffrey-johnson.html in a nutshell, improved Pluvicto: "the SECuRE trial for
I have already talked about this but it continues to look promising, so here is an update: https://www.urotoday.com/video-lectures/asco-2024/video-2/mediaitem/4152-secure-trial-copper-67-psma-therapy-for-prostate-cancer-geoffrey-johnson.html in a nutshell, improved Pluvicto: "the SECuRE trial for
Maxone73
in
Advanced Prostate Cancer
2 months ago
My PBC is getting worse. ascites causing me SOB, confusion, falls. skin is so itchy despite phototherapy. My symptoms are of late stages.
Can anyone help to elevate some symptoms. It's so effecting my life.
Can anyone help to elevate some symptoms. It's so effecting my life.
Oakleypup
in
British Liver Trust
2 months ago
First gene therapy for prevalent pathologies in neurology receives FDA IND clearance - EG 427 initiating first-in-human clinical study
https://uk.finance.yahoo.com/news/first-gene-therapy-prevalent-pathologies-060000901.html
https://uk.finance.yahoo.com/news/first-gene-therapy-prevalent-pathologies-060000901.html
Farooqji
in
Cure Parkinson's
2 months ago
Suppressed TSH on combined therapy
Is there data/medical papers I can give my doctor as to why T3 is suppressed on combination therapy? I have tried looking at the Nice guidelines but they all seem against using combination therapy.Thanks Sue
Is there data/medical papers I can give my doctor as to why T3 is suppressed on combination therapy? I have tried looking at the Nice guidelines but they all seem against using combination therapy.Thanks Sue
redhead41
in
Thyroid UK
2 months ago
Debate on T3 between Prof Bianco & Prof Pearce
These 2 well-known endos had a formal 'debate' recently at the Endo 2024 conference in Boston. Prof Bianco was 'for' the use of T3 in combination therapy, and Prof Pearce was 'against' it. We know that these are their personal stances anyway, even when not in a formal debate setting. Prof Bianco '
These 2 well-known endos had a formal 'debate' recently at the Endo 2024 conference in Boston. Prof Bianco was 'for' the use of T3 in combination therapy, and Prof Pearce was 'against' it. We know that these are their personal stances anyway, even when not in a formal debate setting. Prof Bianco '
TaraJR
in
Thyroid UK
2 months ago
PSP/CBD Symposium - Saturday, June 29, 10am-3pm Pacific (US time)
REGISTRATION IS NOW OPEN Brain Support Network and Stanford's Movement Disorders Center are co-hosting this Progressive Supranuclear Palsy/Corticobasal Degeneration (PSP/CBD) Symposium. This is a hybrid event -- some attending in-person on Stanford's campus and many attending virtually. Who should
REGISTRATION IS NOW OPEN Brain Support Network and Stanford's Movement Disorders Center are co-hosting this Progressive Supranuclear Palsy/Corticobasal Degeneration (PSP/CBD) Symposium. This is a hybrid event -- some attending in-person on Stanford's campus and many attending virtually. Who should
rriddle
in
PSP Association
2 months ago
very hard time today…need support
today I woke up not feeling well. Where I live we’re going through a heat wave. The day before I was outside quite a bit, and I went to a concert so I didn’t get a ton of sleep. I went to breakfast with a friend and then napped for two hours. I felt better and drove home from my boyfriend’s house to
today I woke up not feeling well. Where I live we’re going through a heat wave. The day before I was outside quite a bit, and I went to a concert so I didn’t get a ton of sleep. I went to breakfast with a friend and then napped for two hours. I felt better and drove home from my boyfriend’s house to
Daisy425
in
Anxiety and Depression Support
2 months ago
News we've all been waiting for!
Ralph's had the most amazing few days. On Tuesday he had the swallow x-ray and the speech therapist was amazed at the results. Firstly he gave him some sour tasting stuff, which Ralph insisted he tried to see how horrible it was, lol. Then he had barium mixed with water, then barium with yoghurt then
Ralph's had the most amazing few days. On Tuesday he had the swallow x-ray and the speech therapist was amazed at the results. Firstly he gave him some sour tasting stuff, which Ralph insisted he tried to see how horrible it was, lol. Then he had barium mixed with water, then barium with yoghurt then
Gardenview10
in
British Heart Foundation
2 months ago
Bio Feedback
Has anyone had success with biofeedback? Our son is 13 and had dyspraxia, he can't locate his pelvic floor so as to engage the sensors at the hospital. Anyone have any suggestions on what we could do? We have 5 more sessions (4 hour round trip plus appointment) so it would be good to try and make
Has anyone had success with biofeedback? Our son is 13 and had dyspraxia, he can't locate his pelvic floor so as to engage the sensors at the hospital. Anyone have any suggestions on what we could do? We have 5 more sessions (4 hour round trip plus appointment) so it would be good to try and make
MrsSquirrel
in
ERIC
1 year ago
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