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Now what?
My husband was DX April 2021 MPc, Stage IV, PSA 335, BRACA2. Lupron, Erleada, Provenge, Lynparza (still on), Zytiga/Pred (still on). PSA rose from 2.64 Feb 2023 to 44 Sept 2023. Biggest jumps on the last three months, 10 to 44. He is approved for 177lu, but there are a lot of unsuccessful stories
My husband was DX April 2021 MPc, Stage IV, PSA 335, BRACA2. Lupron, Erleada, Provenge, Lynparza (still on), Zytiga/Pred (still on). PSA rose from 2.64 Feb 2023 to 44 Sept 2023. Biggest jumps on the last three months, 10 to 44. He is approved for 177lu, but there are a lot of unsuccessful stories
Hidden
in
Advanced Prostate Cancer
8 months ago
PSA still low but cancer progressing
I've been on ADT plus Xtandi for about a year (see my profile) and my PSA has steadily reduced and stayed low. However, my latest CT scan shows that the tumours on my bones and lymph nodes are increasing in size and there are now a few small lesions appearing in my liver for the first time. Not the news
I've been on ADT plus Xtandi for about a year (see my profile) and my PSA has steadily reduced and stayed low. However, my latest CT scan shows that the tumours on my bones and lymph nodes are increasing in size and there are now a few small lesions appearing in my liver for the first time. Not the news
Benkaymel
in
Advanced Prostate Cancer
8 months ago
Update and about to start Radiation
Hi all - just a summary so far. Have been doing the triplet and recently finished the 6 sessions of chemo. Had my CT and Bone scans and then follow up with MO on Friday. All is as we expect - nothing shown in CT. Bone scan shows no new "uptake" in the mets places and nothing new. PSA at .41. I am
Hi all - just a summary so far. Have been doing the triplet and recently finished the 6 sessions of chemo. Had my CT and Bone scans and then follow up with MO on Friday. All is as we expect - nothing shown in CT. Bone scan shows no new "uptake" in the mets places and nothing new. PSA at .41. I am
Yzinger
in
Advanced Prostate Cancer
2 months ago
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Am I candidate for AS?
66 year old, Dx January 2022 PSA peak 5.76 [u]Biopsy 3/15/22[/u] 3 of 14 cores PCa 1 of 4 cores, 4+3, 80% Gr 4, <5% of tissue, left posterior 2 of 2 cores, 3+4, 20% Gr 4, 20% of tissue, left mid Decipher .34, cut off for low aggression is .45 NanoKnife June 6, 2022 PSA nadir 1.21 [u]Biopsy 5/16
66 year old, Dx January 2022 PSA peak 5.76 [u]Biopsy 3/15/22[/u] 3 of 14 cores PCa 1 of 4 cores, 4+3, 80% Gr 4, <5% of tissue, left posterior 2 of 2 cores, 3+4, 20% Gr 4, 20% of tissue, left mid Decipher .34, cut off for low aggression is .45 NanoKnife June 6, 2022 PSA nadir 1.21 [u]Biopsy 5/16
Piano777
in
Prostate Cancer Network
8 months ago
Whole pelvic radiation after testicular cancer?
My husband is 63, dx Oct/2022 with PSA of ~11 and all twelve cores positive with GL 8 and mostly 9’s (4+5). He had SVI, PNI, and probable ECE, but PSMA PET showed no spread. He’s being treated at UCHealth/Denver CO at their urologic cancer center. His treatment consisted of 39 radiation sessions +
My husband is 63, dx Oct/2022 with PSA of ~11 and all twelve cores positive with GL 8 and mostly 9’s (4+5). He had SVI, PNI, and probable ECE, but PSMA PET showed no spread. He’s being treated at UCHealth/Denver CO at their urologic cancer center. His treatment consisted of 39 radiation sessions +
Adendino
in
Advanced Prostate Cancer
8 months ago
Just feeling down
Hi Group, To get to it, my PSA recently jumped back up about 60%. It’s now over 1600 after lowering to around 1000. . I’m just learning to manage radiation side effects - to the extent I can - and trying to move back into some “normal” or at least semi-stable state. Then last night my partner admitted
Hi Group, To get to it, my PSA recently jumped back up about 60%. It’s now over 1600 after lowering to around 1000. . I’m just learning to manage radiation side effects - to the extent I can - and trying to move back into some “normal” or at least semi-stable state. Then last night my partner admitted
Arel8
in
Advanced Prostate Cancer
8 months ago
Newly diagnosed
Hi everyone. I was recently diagnosed with non metastatic, but aggressive pc. My psa in March of this year was 8.2 and then 10.1 four months later, so rising quickly. Biopsy was done at end of August, which showed significant tumor development on the right side and a Gleason score of 4,5 or 5,4 in half
Hi everyone. I was recently diagnosed with non metastatic, but aggressive pc. My psa in March of this year was 8.2 and then 10.1 four months later, so rising quickly. Biopsy was done at end of August, which showed significant tumor development on the right side and a Gleason score of 4,5 or 5,4 in half
Quarky
in
Advanced Prostate Cancer
8 months ago
Gleason 6, 1 Yr AS, now Gleason 3+4
Hi, I'm 65, fit, active. , 2 yrs ago noticed PSA doubled to 2.4, last yr 3.5 so had MRI and urine exosome test, "liquid biopsy". Range is 1-100, less than 15 and you are ok, o/w suggest a biopsy. Mine was 48. Oh, the 3 markers in this test are for more aggressive disease. BTW MRI only showed diffuse
Hi, I'm 65, fit, active. , 2 yrs ago noticed PSA doubled to 2.4, last yr 3.5 so had MRI and urine exosome test, "liquid biopsy". Range is 1-100, less than 15 and you are ok, o/w suggest a biopsy. Mine was 48. Oh, the 3 markers in this test are for more aggressive disease. BTW MRI only showed diffuse
Muggs1
in
Prostate Cancer Network
8 months ago
At what point for scan ?
Hi. Currently just had # 4 chemo. Live in Canada so PSMA has never been done . Bone scan and CT scan. I'm wondering at what point it would be good to get a scan ( they already said it would probably be a CT scan as that's all we have in my province and eventually another bone scan which He has to fly
Hi. Currently just had # 4 chemo. Live in Canada so PSMA has never been done . Bone scan and CT scan. I'm wondering at what point it would be good to get a scan ( they already said it would probably be a CT scan as that's all we have in my province and eventually another bone scan which He has to fly
positive-thinking
in
Advanced Prostate Cancer
2 months ago
PSMA Results
Well, PSMA Pylarify scan yesterday was basically unremarkable EXCEPT for the following: Lymph Nodes: New radiotracer avid subcentimeter right common iliac node (image266) and a subcentimeter right pelvic sidewall/obturator lymph node (image 295). IMPRESSION: PSMA avid right common iliac and right
Well, PSMA Pylarify scan yesterday was basically unremarkable EXCEPT for the following: Lymph Nodes: New radiotracer avid subcentimeter right common iliac node (image266) and a subcentimeter right pelvic sidewall/obturator lymph node (image 295). IMPRESSION: PSMA avid right common iliac and right
Cancer2x
in
Advanced Prostate Cancer
8 months ago
Adding Docetaxel to T3b?
My husband is 63, stage T3b N0M0. His biopsy showed all 12 cores positive with 80%+ cancer, GL 4+5 with
intraductal carcinoma
and original PSA was 12. According to PSMA pet scan 12 months ago, he has additional risk factors such as
ECE, SVI, PNI
, but no other spread. He has completed 39
My husband is 63, stage T3b N0M0. His biopsy showed all 12 cores positive with 80%+ cancer, GL 4+5 with
intraductal carcinoma
and original PSA was 12. According to PSMA pet scan 12 months ago, he has additional risk factors such as
ECE, SVI, PNI
, but no other spread. He has completed 39
Adendino
in
Advanced Prostate Cancer
5 months ago
clioquinol + zinc
PSA 44 started clioquinol +zinc Aug 11. Aug 30 PSA 48 with severe UTI. U of Maryland says Clio + zinc kills cancer cells. They give two cases of prostate cancer terminated. I'm trying it.
PSA 44 started clioquinol +zinc Aug 11. Aug 30 PSA 48 with severe UTI. U of Maryland says Clio + zinc kills cancer cells. They give two cases of prostate cancer terminated. I'm trying it.
agnut
in
Advanced Prostate Cancer
8 months ago
Update to: "Newly detectable PSA after prostatectomy: RT + ADT planned; add Erleada?"
Thanks for all the input to my original post. First, here is an administrative posting/question: am I correct to add this as a new post, or should I have posted this as a reply to my original post? Here are some additional details regarding medication side effects and treatment decision-making for
Thanks for all the input to my original post. First, here is an administrative posting/question: am I correct to add this as a new post, or should I have posted this as a reply to my original post? Here are some additional details regarding medication side effects and treatment decision-making for
Brokedown_Palace
in
Advanced Prostate Cancer
8 months ago
declining psa #6
Gm ladies n gentlemen, I’m here to give my results as I stated after stopping adt, post Rp, radiation n solely using ivermectin, cbd, turmeric n fish oil. My latest reading came in 1.34 down from 1.47 and continues to spiral down from starting this regiment at 1.92. Furthermore, prior to starting ivermectin
Gm ladies n gentlemen, I’m here to give my results as I stated after stopping adt, post Rp, radiation n solely using ivermectin, cbd, turmeric n fish oil. My latest reading came in 1.34 down from 1.47 and continues to spiral down from starting this regiment at 1.92. Furthermore, prior to starting ivermectin
Nfler
in
Advanced Prostate Cancer
8 months ago
PSA up to 150 on Olaprib, any insight on what’s next?
Hi all, my dads history is mostly in my profile but in short he started on Zytiga a year ago. Zytiga worked well but had major side effects and lead to a switch to Erleada. Erleada failed at the time shown in the picture with the orange circle and he switched to Olaprib by the time he got the PSA results
Hi all, my dads history is mostly in my profile but in short he started on Zytiga a year ago. Zytiga worked well but had major side effects and lead to a switch to Erleada. Erleada failed at the time shown in the picture with the orange circle and he switched to Olaprib by the time he got the PSA results
StayingSTRNG
in
Advanced Prostate Cancer
8 months ago
Options when Docetaxel stops working
Hi everyone- My brother was diagnosed with stage 4 prostate cancer in April of 2021. His PSA was 52 at the time of his diagnosis. He went on Lupron and Abiraterone which took his PSA to .03 and kept it low until Oct 2022. It went to 8.9 and his doctor put him on Docetaxel chemo. His PSA has continued
Hi everyone- My brother was diagnosed with stage 4 prostate cancer in April of 2021. His PSA was 52 at the time of his diagnosis. He went on Lupron and Abiraterone which took his PSA to .03 and kept it low until Oct 2022. It went to 8.9 and his doctor put him on Docetaxel chemo. His PSA has continued
TerryR123
in
Advanced Prostate Cancer
8 months ago
Pluvicto Aftereffects SMART syndrome?
As I've posted here, spouse was pretty much the poster boy for Pluvicto. He had a hiccup with the supply issues, but PSA dropped significantly and his side effects during treatment were perfectly manageable, until .... We were heading to NM via West Texas when he began complaining of bright light and
As I've posted here, spouse was pretty much the poster boy for Pluvicto. He had a hiccup with the supply issues, but PSA dropped significantly and his side effects during treatment were perfectly manageable, until .... We were heading to NM via West Texas when he began complaining of bright light and
Biobro
in
Advanced Prostate Cancer
8 months ago
Radiation Interruption
Hi....all the best to your Dad. I have no idea if stopping radiation for a time would m after. I did 5 on 2 days off for 28 treatments. You did not mention any PSA or Gleason number. Not sure that would matter...but someone here might venture another opinion based on those numbers and If he is metastatic
Hi....all the best to your Dad. I have no idea if stopping radiation for a time would m after. I did 5 on 2 days off for 28 treatments. You did not mention any PSA or Gleason number. Not sure that would matter...but someone here might venture another opinion based on those numbers and If he is metastatic
Poppy1952
in
Advanced Prostate Cancer
8 months ago
Active Surveillance
Hello everyone, I have had 2 biopsies in the last 2 years (the last one was in January 2023) with the latest one showing 1 out of 12 cores positive for Gleason 3+3 and another core suspicious for cancer. It was also noted on my last MRI that I had a bladder outlet obstruction. My PSA went as high as
Hello everyone, I have had 2 biopsies in the last 2 years (the last one was in January 2023) with the latest one showing 1 out of 12 cores positive for Gleason 3+3 and another core suspicious for cancer. It was also noted on my last MRI that I had a bladder outlet obstruction. My PSA went as high as
ironmanburg
in
Active Surveillance - Prostate Cancer
8 months ago
Prostate Biopsy
Hello everyone, I have had 2 biopsies in the last 2 years (the last one was in January 2023) with the latest one showing 1 out of 12 cores positive for Gleason 3+3 and another core suspicious for cancer. It was also noted on my last MRI that I had a bladder outlet obstruction. My PSA went as high as
Hello everyone, I have had 2 biopsies in the last 2 years (the last one was in January 2023) with the latest one showing 1 out of 12 cores positive for Gleason 3+3 and another core suspicious for cancer. It was also noted on my last MRI that I had a bladder outlet obstruction. My PSA went as high as
ironmanburg
in
Prostate Cancer Network
8 months ago
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